Some immunology from S94
and S95 WITH VERIFIED
SOLUTIONS
IL-8 - answer attracts neutrophils; also is a chemokine
Kinins - answer vasoactive: they increase vascular permeability
and increase the expression of cellular adhesion molecules, allowing
leukocytes to extravasate into the tissue; localized inflammatory
response
IL-12 - answer activates NK cells
endogenous pyrogens - answer IL-1, IL-6, and TNF-a
MHC class 1 - answer goes with CD8; endogenous antigen, so
viruses; CTLs; only alpha subunit and beta microglobulin molecule;
all nucleated cells
MHC class 2 - answer goes with CD4; exogenous antigen; has alpha
and beta subunit; only monocytes, macrophages, and dendritic cells
and thymus epithelium
IL-12 - answer is the "signature" cytokine for the development of
the TH1 effector cell. T-bet transcription factor
IL-4 - answer is the "signature" cytokine for the development of
the TH2 effector cell. GATA-3 transcription factor; inhibits TH1
and S95 WITH VERIFIED
SOLUTIONS
IL-8 - answer attracts neutrophils; also is a chemokine
Kinins - answer vasoactive: they increase vascular permeability
and increase the expression of cellular adhesion molecules, allowing
leukocytes to extravasate into the tissue; localized inflammatory
response
IL-12 - answer activates NK cells
endogenous pyrogens - answer IL-1, IL-6, and TNF-a
MHC class 1 - answer goes with CD8; endogenous antigen, so
viruses; CTLs; only alpha subunit and beta microglobulin molecule;
all nucleated cells
MHC class 2 - answer goes with CD4; exogenous antigen; has alpha
and beta subunit; only monocytes, macrophages, and dendritic cells
and thymus epithelium
IL-12 - answer is the "signature" cytokine for the development of
the TH1 effector cell. T-bet transcription factor
IL-4 - answer is the "signature" cytokine for the development of
the TH2 effector cell. GATA-3 transcription factor; inhibits TH1
