NU 643 Week 3 Quiz Questions
and Answers All Correct
Electrical change - Answer- occurs across membrane other channels use
neurotransmitter to open channels.
slowest to fastest drug delivery - Answer- Slowest method = oral- slow bc of first pass,
going through stomach, intestine, liver to get to blood stream
Fastest = sublingual/IV
drug absorption - Answer- know what inducers do to concentration of drugs and what
inhibitors do to concentration of other drugs by acting on the enzyme - not the drug itself
pharmacokinetics - Answer- what the body does to the drugs - how it processes
and breaks it down
Pharmacodynamics - Answer- what the drug does to the body - actions of drug on the
Body
concentration-time curve - Answer- time under concentration time curve reflects
exposure to drug after it was administered, and it is dependent upon the rate of
elimination.
Under curve is the time that drug is actually available to be metabolized
How long drug is active and available for body to use
half-life - Answer- is amount of time it take for body to use up half of the drug and
eliminate and is important to know when measuring drug concentrations.
half-life of carbamazepine - Answer- Know half life of carbamazepine =12 hrs for half life
- 5 half lifes to reach steady state = 60 hours or 2.5 days before you can draw a
therapeutic level.
Drug efficiency - Answer- is affected by the degree to which it binds to protein Know that
the less bound a drug to protein = the more efficiently it can diffuse and then can be
used.
phase I - Answer- Deals with cyp450 enzyme system - when drug is broken down to a
more active products
phase II - Answer- when drug is broken down to be excreted and eliminated
and Answers All Correct
Electrical change - Answer- occurs across membrane other channels use
neurotransmitter to open channels.
slowest to fastest drug delivery - Answer- Slowest method = oral- slow bc of first pass,
going through stomach, intestine, liver to get to blood stream
Fastest = sublingual/IV
drug absorption - Answer- know what inducers do to concentration of drugs and what
inhibitors do to concentration of other drugs by acting on the enzyme - not the drug itself
pharmacokinetics - Answer- what the body does to the drugs - how it processes
and breaks it down
Pharmacodynamics - Answer- what the drug does to the body - actions of drug on the
Body
concentration-time curve - Answer- time under concentration time curve reflects
exposure to drug after it was administered, and it is dependent upon the rate of
elimination.
Under curve is the time that drug is actually available to be metabolized
How long drug is active and available for body to use
half-life - Answer- is amount of time it take for body to use up half of the drug and
eliminate and is important to know when measuring drug concentrations.
half-life of carbamazepine - Answer- Know half life of carbamazepine =12 hrs for half life
- 5 half lifes to reach steady state = 60 hours or 2.5 days before you can draw a
therapeutic level.
Drug efficiency - Answer- is affected by the degree to which it binds to protein Know that
the less bound a drug to protein = the more efficiently it can diffuse and then can be
used.
phase I - Answer- Deals with cyp450 enzyme system - when drug is broken down to a
more active products
phase II - Answer- when drug is broken down to be excreted and eliminated
