PHM 714 Exam 5 Questions And Accurate Answers
_______________ reduces renal toxicity associated with repeated administration of
cisplatin - Answer Amifostine
Adverse effects of Cisplatin - Answer Cisplatin-induced nephrotoxicity
Ototoxicity (tinnitus and high-frequency hearing loss)
Nausea & vomiting
Peripheral motor and sensory neuropathy
myelosuppression
Electrolyte disturbances: hypomagnesemia, hypocalcemia, hypokalemia, and
hypophosphatemia, are common
Anaphylactic-like reactions
Which drug has a "Pyrrole pyrimidine structure"? - Answer Pemetrexed (MTA)
Which drug Induces P53 & cell cycle arrest? - Answer Pemetrexed (MTA)
Where did you see this?
"Patients should receive intramuscular vitamin B12 (1 mg) with the first dose of
, pemetrexed to correct possible B12 deficiency" - Answer
SCLC Supportive Care - Answer Smoking Cessation
GM-CSF/G-CSF Use
SIADH
Cushing syndrome
Nausea and Vomiting
SCLC Supportive Care: How do you adress SIADH? - Answer Fluid Restriction
Saline infusions for symptomatic patients
Demeclocycline
Vasopressin receptor inhibitors (i.e. conivaptan, tolvaptan)
(CINV)
What are the 5HT3-receptor antagonists? - Answer Dolasetron (PO)
Ondansetron (PO, IV)
Granisetron (PO, IV, subQ, TD patch)
Palonosetron (IV)
"DOG Pee"
___________ is the only effective drug for anticipatory CINV - Answer Lorazepam
Which drugs are "better suited for delayed CINV"? - Answer Dexamethasone,
neurokinin-1 inhibitors and olanzapine
Which class of drugs are mostly appropriate for acute CINV? - Answer 5HT3-receptor
antagonists
_______________ reduces renal toxicity associated with repeated administration of
cisplatin - Answer Amifostine
Adverse effects of Cisplatin - Answer Cisplatin-induced nephrotoxicity
Ototoxicity (tinnitus and high-frequency hearing loss)
Nausea & vomiting
Peripheral motor and sensory neuropathy
myelosuppression
Electrolyte disturbances: hypomagnesemia, hypocalcemia, hypokalemia, and
hypophosphatemia, are common
Anaphylactic-like reactions
Which drug has a "Pyrrole pyrimidine structure"? - Answer Pemetrexed (MTA)
Which drug Induces P53 & cell cycle arrest? - Answer Pemetrexed (MTA)
Where did you see this?
"Patients should receive intramuscular vitamin B12 (1 mg) with the first dose of
, pemetrexed to correct possible B12 deficiency" - Answer
SCLC Supportive Care - Answer Smoking Cessation
GM-CSF/G-CSF Use
SIADH
Cushing syndrome
Nausea and Vomiting
SCLC Supportive Care: How do you adress SIADH? - Answer Fluid Restriction
Saline infusions for symptomatic patients
Demeclocycline
Vasopressin receptor inhibitors (i.e. conivaptan, tolvaptan)
(CINV)
What are the 5HT3-receptor antagonists? - Answer Dolasetron (PO)
Ondansetron (PO, IV)
Granisetron (PO, IV, subQ, TD patch)
Palonosetron (IV)
"DOG Pee"
___________ is the only effective drug for anticipatory CINV - Answer Lorazepam
Which drugs are "better suited for delayed CINV"? - Answer Dexamethasone,
neurokinin-1 inhibitors and olanzapine
Which class of drugs are mostly appropriate for acute CINV? - Answer 5HT3-receptor
antagonists
