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GMS 6530 Hypertension Exam Questions And Accurate Answers Latest Update

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GMS 6530 Hypertension Exam Questions And Accurate Answers Latest Update...

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GMS 6530 Hypertension Exam Questions And Accurate
Answers Latest Update


Diuretics - Answer - hydrochlorothiazide

- acute -lower BV

- chronic - lower TPR

- adverse - hypoK, alkalosis, increase LDL, gout, type II diabetes, ED



ACEI - Answer - prils

- lower TPR

- lower aldosterone

- may increase bradykinin & prostaglandin



ACEI side effects - Answer - 1st dose hypotension

- cough (5-20%)

- fetopathic renal impairment

- angioedema

- hyperkalemia



ARBS - Answer - sartans

- blocks ANGII receptors

- lowers TPR



ARBS side effects - Answer - hypotension

- fetopathic potential

hyperkalemia

, CCB - Answer - N, D, V

block L-type channels

decrease TPR - DHPs > D > V

decrease HR - V ≥ D

decrease contractility - V ≥ D



CCB side effects - Answer - edema/fluid retention

headache, flushing, dizziness - hypotension related

bradycardia

reflex tachycardia - DHPs



CCB precautions (V,D) - Answer - SA or AV nodal abnormalities

concurrent BB usage

HF

T1/2 increases with hepatic impairment



DHPs - Answer - dihydropyridines

- amlodipine, felodipine, nimodipine

- less reflex tachycardia



Amlodipine - Answer - slow onset of action

- long half life



Nimodipine - Answer - more cerebral dilation



Aldosterone antagonists - Answer - spironolactone, eplerenone

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