2024 /2025 | © copyright | This work may not be copied for profit gain Excel!
Hematology CSMLS Questions and Correct
Answers | Latest Update
Adult Hematopoiesis
✓ -:- Skull, sternum, pelvis, ribs and vertebrae.
✓ Flat bones: active adult hemopoietic tissue (colony forming units in red
marrow)
Prenatal hematopoiesis
✓ -:- Begins in the yolk sac, then fetal liver, and then bone marrow at
birth
Hemoglobin
✓ -:- An iron-containing protein in red blood cells that reversibly binds
oxygen.
- Must have iron and protoporphyrin
Transferrin
✓ -:- iron transport protein
1 | P a g e | G r a d e A + | 2 0 0 2 5
,2024 /2025 | © copyright | This work may not be copied for profit gain Excel!
Ferritin
✓ -:- Major Fe Storage form
Hemosiderin
✓ -:- H2O insoluble Fe storage form (long term)
Hemosiderosis
✓ -:- abnormal increase of iron in blood, excess iron stored in tissues and
body organs
Early Heme Precursors
✓ -:- Delta-aminolevulinic acid
Porphobilinogen
Late Heme Precursors
✓ -:- Uroporphyrinogen
2 | P a g e | G r a d e A + | 2 0 0 2 5
,2024 /2025 | © copyright | This work may not be copied for profit gain Excel!
-
Coproporphyrinogen
- Protoporphyrin
- Heme
Shift to Left Hgb-O2 Dissociation
✓ -:- O2 not released to tissue adequately
- Decreased CO2
- Increased pH
- HbF (High affinity Hb)
- Multiple transfusions (Decreased 2,3-DPG)
Shift to Right Hgb-O2 Dissociation
✓ -:- O2 released to tissue more easily
- Increased CO2
3 | P a g e | G r a d e A + | 2 0 0 2 5
, 2024 /2025 | © copyright | This work may not be copied for profit gain Excel!
-
Decreased pH
- Increased 2,3-DPG
HbF
✓ -:- Fetal hemoglobin
A2Y2. 2 alpha, 2 gamma chains
60-90% in Newborns
Hgb A2
✓ -:- 2 alpha and 2 delta
<2% newborn
2% Adult
Hgb A
✓ -:- 2 Alpha and 2 Beta chains. Adult hemoglobin
4 | P a g e | G r a d e A + | 2 0 0 2 5
Hematology CSMLS Questions and Correct
Answers | Latest Update
Adult Hematopoiesis
✓ -:- Skull, sternum, pelvis, ribs and vertebrae.
✓ Flat bones: active adult hemopoietic tissue (colony forming units in red
marrow)
Prenatal hematopoiesis
✓ -:- Begins in the yolk sac, then fetal liver, and then bone marrow at
birth
Hemoglobin
✓ -:- An iron-containing protein in red blood cells that reversibly binds
oxygen.
- Must have iron and protoporphyrin
Transferrin
✓ -:- iron transport protein
1 | P a g e | G r a d e A + | 2 0 0 2 5
,2024 /2025 | © copyright | This work may not be copied for profit gain Excel!
Ferritin
✓ -:- Major Fe Storage form
Hemosiderin
✓ -:- H2O insoluble Fe storage form (long term)
Hemosiderosis
✓ -:- abnormal increase of iron in blood, excess iron stored in tissues and
body organs
Early Heme Precursors
✓ -:- Delta-aminolevulinic acid
Porphobilinogen
Late Heme Precursors
✓ -:- Uroporphyrinogen
2 | P a g e | G r a d e A + | 2 0 0 2 5
,2024 /2025 | © copyright | This work may not be copied for profit gain Excel!
-
Coproporphyrinogen
- Protoporphyrin
- Heme
Shift to Left Hgb-O2 Dissociation
✓ -:- O2 not released to tissue adequately
- Decreased CO2
- Increased pH
- HbF (High affinity Hb)
- Multiple transfusions (Decreased 2,3-DPG)
Shift to Right Hgb-O2 Dissociation
✓ -:- O2 released to tissue more easily
- Increased CO2
3 | P a g e | G r a d e A + | 2 0 0 2 5
, 2024 /2025 | © copyright | This work may not be copied for profit gain Excel!
-
Decreased pH
- Increased 2,3-DPG
HbF
✓ -:- Fetal hemoglobin
A2Y2. 2 alpha, 2 gamma chains
60-90% in Newborns
Hgb A2
✓ -:- 2 alpha and 2 delta
<2% newborn
2% Adult
Hgb A
✓ -:- 2 Alpha and 2 Beta chains. Adult hemoglobin
4 | P a g e | G r a d e A + | 2 0 0 2 5
