NR 567 Advanced Pharmacology Final Exam New
2025 Version with All Questions from Actual Past
Exam and 100% Correct Answers
Which of the following antimalarial drugs is also used to treat autoimmune disorders? -----------
Correct Answer ------------- Hydroxychloroquine (Plaquenil)
A 41-year-old female is started on treatment for breast cancer with tamoxifen following surgical
resection. Following five years of completed tamoxifen therapy, which of the following
medications should the patient receive? ----------- Correct Answer ------------- Anastrozole
(Arimidex)
Which of the following is the least preferable initial treatment of choice for status epilepticus? ---
-------- Correct Answer ------------- Propofol (Diprivan)
Which of the following statements is not true? ----------- Correct Answer ------------- Sedative
hypnotics can be utilized as an anticonvulsant; zolpidem (Ambien) and lorazepam (Ativan) are
excellent options for managing seizures.- Zolpidem is not used as an anti-seizure
Your patient has been taking risperidone (Risperdal) but has developed hyperprolactinemia.
Which of the following may help manage hyperprolactinemia? ----------- Correct Answer ---------
---- Bromocriptine (Parlodel)
Principles that guide the selection of drugs of combination chemotherapy in the treatment of
cancer include all of the following except___? ----------- Correct Answer ------------- Arbitrary
dose changes
Which of the following statements best describes why propranolol (Inderal) can be used as an
adjunct for patients with side effects from thyroid replacement therapy? ----------- Correct
Answer ------------- The drug blocks thyroid hormone release directly on the gland
Following thyroidectomy, which medication is required indefinitely? ----------- Correct Answer -
------------ Levothyroxine (Synthroid)
Which of the following pharmacological agents can be used as a temporary inhibitor of
corticosteroid synthesis in Cushing's disease? ----------- Correct Answer -------------
Ketoconazole (Nizoral)
Which of the following adverse reactions should be monitored when prescribing propylthiouracil
(PTU)? ----------- Correct Answer ------------- Agranulocytosis
Which of the following statements best describes the properties of Levothyroxine? -----------
Correct Answer ------------- It converts T4 to T3 intracellularly-administration of the drug
produces both hormones so that separate T3 administration is unnecessary
,Glucocorticoids have which of the following actions? ----------- Correct Answer -------------
Decrease antibody production
Which of the following insulins has the most rapid onset of action? ----------- Correct Answer ----
--------- Lispro (Humalog)
A 28-year-old male presents with symptoms consistent with diabetic ketoacidosis. Serum
glucose is 470mg/dL and serum potassium level is 4.0 mEq/L. Which of the following is the
expected course of action? ----------- Correct Answer ------------- Insulin infusion at
0.1units/kg/hr with intravenous 0.9% normal saline and potassium replacement
Which of the following medication classes is the least likely to cause the adverse effect of
hypoglycemia? ----------- Correct Answer ------------- Biguanide
Which of the following is included in the treatment of hyperosmolar, hyperglycemic syndrome>
----------- Correct Answer ------------- Aggressive rehydration with 0.9% NS intravenously and
correction of electrolyte abnormalities
When prescribing intravenous acyclovir (Zovirax), the nurse practitioner knows that: -----------
Correct Answer ------------- Adequate hydration should also be maintained
A 13-year-old male with moderately persistent asthma has been diagnosed with type A influenza.
Which of the following statements is the most important to consider when prescribing treatment
with oseltamivir (Tamiflu)? ----------- Correct Answer ------------- the medication should be
started within the first 48 hours of influenza symptoms
If considering starting a patient on the nucleoside reverse transcriptase inhibitor abacavir
(Ziagen) which of the following is recommended prior to prescribing the medication? -----------
Correct Answer ------------- HLA B*5701 testing
The drug of choice for the treatment of disease due to Histoplasma? ----------- Correct Answer ---
---------- Itraconazole (Sporanox)
Which of the following statements is true regarding metronidazole (Flagyl)? ----------- Correct
Answer ------------- Alcohol should be avoided
Which of the following drugs is the standard chemoprophylactic agent for the prevention of P
jiroveci infection (the cause of human pneumocystosis) in an immunocompromised patient? -----
------ Correct Answer ------------- Trimethoprim-sulfamethoxazole (TMP-SMX)
You are treating a patient for fungemia with amphotericin B. The nurse practitioner knows which
of the following is a common complication of treatment? ----------- Correct Answer -------------
Renal failure
Which of the following, used in combination with sulfadiazine, is considered first-line therapy to
, treat toxoplasmosis? ----------- Correct Answer ------------- Pyrimethamine (Daraprim)
Which of the following drugs is the treatment of choice for uncomplicated non-falciparum and
sensitive falciparum malaria? ----------- Correct Answer ------------- Chloroquine (Aralen)
All of the following are goals of treatment of acute hepatitis B infection, except: -----------
Correct Answer ------------- Viral eradication
Which of the following medications should be given to patients presenting to the emergency
department (ED) with an altered level of consciousness, seizures, or both, if a concern of
Wernicke-Korsakoff syndrome exists? ----------- Correct Answer ------------- Thiamine
Which of the following pharmaceutical agents is not recommended for treating methanol
poisoning? ----------- Correct Answer ------------- Antabuse
Which of the following pharmaceutical agents is the preferred antiseizure medication for a
generalized seizure disorder in a 25-year -old pregnant female? ----------- Correct Answer --------
----- Levetiracetam (Keppra)
A 35-year-old female with a long history of anxiety treated with diazepam (Valium) has
increasingly become fearful and anxious about the Coronavirus pandemic and triples her daily
dose. She is found extremely lethargic and obtunded two days after the increased dosing. Which
of the following pharmaceutical agents should the nurse practitioner order to treat her condition?
----------- Correct Answer ------------- Flumazenil (Romazicon)
A 25-year-old male with a history of bipolar disease presents to the emergency department (ED)
with acute agitation characteristic of mania. Non-pharmacological methods of de-escalation have
been attempted without success. Which of the following is not recommended to treat this
patient? ----------- Correct Answer ------------- Olanzapine (Zyprexa)
Which of the following is a long-acting benzodiazepine that is used to treat anxiety? -----------
Correct Answer ------------- Diazepam (Valium)
Acute dystonia can develop after early initiation of which of the following? ----------- Correct
Answer ------------- halodol
Adding epinephrine to a local anesthetic, such as 1% lidocaine for local infiltration, has which of
the following benefits? ----------- Correct Answer ------------- Extends the duration of the
anesthesia block, useful for longer procedures
Your patient reports a history of anaphylaxis to an "ester-type" local anesthetic. Which of the
following, if given, would be most likely to provoke an allergic response in this patient? ----------
- Correct Answer ------------- Tetracaine (Pontocaine)
An OR patient receives propofol for induction. What is the most likely adverse response
associated with the administration of this pharmaceutical agent? ----------- Correct Answer -------
2025 Version with All Questions from Actual Past
Exam and 100% Correct Answers
Which of the following antimalarial drugs is also used to treat autoimmune disorders? -----------
Correct Answer ------------- Hydroxychloroquine (Plaquenil)
A 41-year-old female is started on treatment for breast cancer with tamoxifen following surgical
resection. Following five years of completed tamoxifen therapy, which of the following
medications should the patient receive? ----------- Correct Answer ------------- Anastrozole
(Arimidex)
Which of the following is the least preferable initial treatment of choice for status epilepticus? ---
-------- Correct Answer ------------- Propofol (Diprivan)
Which of the following statements is not true? ----------- Correct Answer ------------- Sedative
hypnotics can be utilized as an anticonvulsant; zolpidem (Ambien) and lorazepam (Ativan) are
excellent options for managing seizures.- Zolpidem is not used as an anti-seizure
Your patient has been taking risperidone (Risperdal) but has developed hyperprolactinemia.
Which of the following may help manage hyperprolactinemia? ----------- Correct Answer ---------
---- Bromocriptine (Parlodel)
Principles that guide the selection of drugs of combination chemotherapy in the treatment of
cancer include all of the following except___? ----------- Correct Answer ------------- Arbitrary
dose changes
Which of the following statements best describes why propranolol (Inderal) can be used as an
adjunct for patients with side effects from thyroid replacement therapy? ----------- Correct
Answer ------------- The drug blocks thyroid hormone release directly on the gland
Following thyroidectomy, which medication is required indefinitely? ----------- Correct Answer -
------------ Levothyroxine (Synthroid)
Which of the following pharmacological agents can be used as a temporary inhibitor of
corticosteroid synthesis in Cushing's disease? ----------- Correct Answer -------------
Ketoconazole (Nizoral)
Which of the following adverse reactions should be monitored when prescribing propylthiouracil
(PTU)? ----------- Correct Answer ------------- Agranulocytosis
Which of the following statements best describes the properties of Levothyroxine? -----------
Correct Answer ------------- It converts T4 to T3 intracellularly-administration of the drug
produces both hormones so that separate T3 administration is unnecessary
,Glucocorticoids have which of the following actions? ----------- Correct Answer -------------
Decrease antibody production
Which of the following insulins has the most rapid onset of action? ----------- Correct Answer ----
--------- Lispro (Humalog)
A 28-year-old male presents with symptoms consistent with diabetic ketoacidosis. Serum
glucose is 470mg/dL and serum potassium level is 4.0 mEq/L. Which of the following is the
expected course of action? ----------- Correct Answer ------------- Insulin infusion at
0.1units/kg/hr with intravenous 0.9% normal saline and potassium replacement
Which of the following medication classes is the least likely to cause the adverse effect of
hypoglycemia? ----------- Correct Answer ------------- Biguanide
Which of the following is included in the treatment of hyperosmolar, hyperglycemic syndrome>
----------- Correct Answer ------------- Aggressive rehydration with 0.9% NS intravenously and
correction of electrolyte abnormalities
When prescribing intravenous acyclovir (Zovirax), the nurse practitioner knows that: -----------
Correct Answer ------------- Adequate hydration should also be maintained
A 13-year-old male with moderately persistent asthma has been diagnosed with type A influenza.
Which of the following statements is the most important to consider when prescribing treatment
with oseltamivir (Tamiflu)? ----------- Correct Answer ------------- the medication should be
started within the first 48 hours of influenza symptoms
If considering starting a patient on the nucleoside reverse transcriptase inhibitor abacavir
(Ziagen) which of the following is recommended prior to prescribing the medication? -----------
Correct Answer ------------- HLA B*5701 testing
The drug of choice for the treatment of disease due to Histoplasma? ----------- Correct Answer ---
---------- Itraconazole (Sporanox)
Which of the following statements is true regarding metronidazole (Flagyl)? ----------- Correct
Answer ------------- Alcohol should be avoided
Which of the following drugs is the standard chemoprophylactic agent for the prevention of P
jiroveci infection (the cause of human pneumocystosis) in an immunocompromised patient? -----
------ Correct Answer ------------- Trimethoprim-sulfamethoxazole (TMP-SMX)
You are treating a patient for fungemia with amphotericin B. The nurse practitioner knows which
of the following is a common complication of treatment? ----------- Correct Answer -------------
Renal failure
Which of the following, used in combination with sulfadiazine, is considered first-line therapy to
, treat toxoplasmosis? ----------- Correct Answer ------------- Pyrimethamine (Daraprim)
Which of the following drugs is the treatment of choice for uncomplicated non-falciparum and
sensitive falciparum malaria? ----------- Correct Answer ------------- Chloroquine (Aralen)
All of the following are goals of treatment of acute hepatitis B infection, except: -----------
Correct Answer ------------- Viral eradication
Which of the following medications should be given to patients presenting to the emergency
department (ED) with an altered level of consciousness, seizures, or both, if a concern of
Wernicke-Korsakoff syndrome exists? ----------- Correct Answer ------------- Thiamine
Which of the following pharmaceutical agents is not recommended for treating methanol
poisoning? ----------- Correct Answer ------------- Antabuse
Which of the following pharmaceutical agents is the preferred antiseizure medication for a
generalized seizure disorder in a 25-year -old pregnant female? ----------- Correct Answer --------
----- Levetiracetam (Keppra)
A 35-year-old female with a long history of anxiety treated with diazepam (Valium) has
increasingly become fearful and anxious about the Coronavirus pandemic and triples her daily
dose. She is found extremely lethargic and obtunded two days after the increased dosing. Which
of the following pharmaceutical agents should the nurse practitioner order to treat her condition?
----------- Correct Answer ------------- Flumazenil (Romazicon)
A 25-year-old male with a history of bipolar disease presents to the emergency department (ED)
with acute agitation characteristic of mania. Non-pharmacological methods of de-escalation have
been attempted without success. Which of the following is not recommended to treat this
patient? ----------- Correct Answer ------------- Olanzapine (Zyprexa)
Which of the following is a long-acting benzodiazepine that is used to treat anxiety? -----------
Correct Answer ------------- Diazepam (Valium)
Acute dystonia can develop after early initiation of which of the following? ----------- Correct
Answer ------------- halodol
Adding epinephrine to a local anesthetic, such as 1% lidocaine for local infiltration, has which of
the following benefits? ----------- Correct Answer ------------- Extends the duration of the
anesthesia block, useful for longer procedures
Your patient reports a history of anaphylaxis to an "ester-type" local anesthetic. Which of the
following, if given, would be most likely to provoke an allergic response in this patient? ----------
- Correct Answer ------------- Tetracaine (Pontocaine)
An OR patient receives propofol for induction. What is the most likely adverse response
associated with the administration of this pharmaceutical agent? ----------- Correct Answer -------
