MLT ASCP BOC Blood Bank NEWEST EXAM
VERSION QUESTIONS WITH GOLDEN TIPS
SOLUTIONS 100% CORRECT
A blood donor has totype: hh, AB. ing anti-A and anti-B antisera., the donor's red cells
will type as group US? - <<ANSWER>>O
which of the following is proper procedure for preparation of platelets from Whole
blood? - <<ANSWER>>light spin followed by a hard spin
The minimum hemoglobin concentration in a finger-stick from a male blood donor is: -
<<ANSWER>>13.0 g/dL
A cause for indefinite deferral of blood donation is: - <<ANSWER>>Positive test for
Trypanosoma cruzi
What of the following prospective donors would be accepted for donation? -
<<ANSWER>>22-year-old college student who has a temperature of 99.2 degrees F
(37.7 C) and states that he feels well, but is nervous about donating
Which of the following constitutes permanent deferral status of a donor? -
<<ANSWER>>Confirmed positive test for HBsAg 10 years previously
According to AABB standards, which of the following donors may be accepted as a
blood donor? - <<ANSWER>>Spontaneous abortion at 2 months of pregnancy, 3
months previously
A patient received 4 units of blood 2 years previously and now has multiple antibodies.
He has not been transfused since that time. It would be most helpful to: -
<<ANSWER>>phenotype his cells to determine which additional alloantibodies may be
produced
autoantibodies demonstrating blood group specificity in warm autoimmune hemolytic
anemia are associated more often with which blood group system? - <<ANSWER>>Rh
An antibody that causes in vitro hemolysis and reacts with the red cells of 3 out of 10
AHG-crossmatched donor units is most likely: - <<ANSWER>>anti-Le^a
,36, 37 ,38 pg - <<ANSWER>>A, B, D, B
in the process of identifying an antibody, the technologist observed 2+ reactions with 3
of the 10 cells in a panel after the immediate spin phase. There was no reactivity after
incubation at 37 oC and after the anti-human globulin test phase. The antibody most
likely is: - <<ANSWER>>anti-Le^a
Transfusion of Ch+ (Chido-positive) red cells to a patient with anti-Ch has been reported
to cause: - <<ANSWER>>no clinically significant red cell destruction
which characteristics are true of ALL 3 of the following antibodies: anti-Fy^a, anti-Jk^a,
and anti-K? - <<ANSWER>>detected at IAT phase and may cause hemolytic disease of
the fetus and newborn (HDFN) and transfusion reactions
38,39 - <<ANSWER>>C, B
which of the following test is most commonly used to detect antibodies attached to a
patient's red blood cells in vivo? - <<ANSWER>>direct antiglobulin
Anti-I inn cold agglutinin disease may cause a positive direct antiglobulin test (DAT)
because of: - <<ANSWER>>C3d bound to the red cells
a patient's antibody identification panel demonstrated anti-M. The antibody was most
reactive with homozygous M+ cells compared to heterozygous M+ cells. Which of the
following cells would demonstrate the strongest reaction? - <<ANSWER>>M+N-S-s+
in the direct antigloulin test, the antiglobulin reagent is used to: - <<ANSWER>>detect
preexisting antibodies on erythrocytes
the mechanism that best explains hemolytic anemia due to penicillin is: -
<<ANSWER>>drug-dependent antibodies reacting with drug-treated cells
Use of EDTA plasma prevents activation of the classical complement pathway by: -
<<ANSWER>>chelating Mg++ ions, which prevents assembly of C6chelating Ca++ions,
which prevents assembly of C1
the drug cephalosporin can cause a positive direct antiglobulin test due to modification
of the RBC membrane by the drug which is independent of antibody production. This
mechanism related to the drug cephalosporin is best described as: -
<<ANSWER>>nonimmunologic protein adsorption
During prenatal studies, a woman is noted to have a positive antibody screen and anti-
Kp^a is identified. What percentage of units will be compatible for this patient if
transfusion is necessary? - <<ANSWER>>>98%
the purpose of testing with anti-A,B is to detect: - <<ANSWER>>subgroups of A
, A group O, Rh-negative pregnant female has anti-Vel in her serum. If needed, how
might blood be provided for her infant? - <<ANSWER>>maternal donation
diagram - pg. 41, #260 - <<ANSWER>>B
while performing an antibody screen, a test reaction is suspected to be rouleaux. A
saline replacement test is performed and the reaction remains. What is the best
interpretation? - <<ANSWER>>original reaction was due to true agglutination
diagram - pg. 41, #262 - <<ANSWER>>A
Mixed field agglutination encountered in ABO grouping with no history of transfusion
would most likely be due to: - <<ANSWER>>A3 red cells
A patient demonstrates 4+ reactivity with all red cells tested and the autocontrol is
nonreactive. This high incidence antibody was suspected to be related to the P1PK
blood group system as the patient is the rare p phenotype. What antibody specificity
should be suspected? - <<ANSWER>>anti-PP1P^k
using the antigen typing results below, what is the patient's likely phenotype?
D+
C0
E+
c+
e+
f+
G + - <<ANSWER>>R2r
a patient received 2 units of RBC and had a delayed transfusion reaction.
Pretransfusion antibody screening records indicate no agglutination except after the
addition of IgG-sensitized cells. Repeat testing of the pretransfusion specimen detected
an antibody at the antiglobulin phase. What is the most likely explanation for the original
results? - <<ANSWER>>patient's serum was omitted from the original testing
In order to be a plateletpheresis donor, the platelet count must be at least: -
<<ANSWER>>150,000/ul
Prior to blood donation, the intended venipuncture site must be cleaned with a scrub
solution containing: - <<ANSWER>>Providone iodine
A donor who has just donated 2 units of Apheresis Red Blood Cells will be deferred
from further blood donation for a minimum of how many weeks? - <<ANSWER>>16
VERSION QUESTIONS WITH GOLDEN TIPS
SOLUTIONS 100% CORRECT
A blood donor has totype: hh, AB. ing anti-A and anti-B antisera., the donor's red cells
will type as group US? - <<ANSWER>>O
which of the following is proper procedure for preparation of platelets from Whole
blood? - <<ANSWER>>light spin followed by a hard spin
The minimum hemoglobin concentration in a finger-stick from a male blood donor is: -
<<ANSWER>>13.0 g/dL
A cause for indefinite deferral of blood donation is: - <<ANSWER>>Positive test for
Trypanosoma cruzi
What of the following prospective donors would be accepted for donation? -
<<ANSWER>>22-year-old college student who has a temperature of 99.2 degrees F
(37.7 C) and states that he feels well, but is nervous about donating
Which of the following constitutes permanent deferral status of a donor? -
<<ANSWER>>Confirmed positive test for HBsAg 10 years previously
According to AABB standards, which of the following donors may be accepted as a
blood donor? - <<ANSWER>>Spontaneous abortion at 2 months of pregnancy, 3
months previously
A patient received 4 units of blood 2 years previously and now has multiple antibodies.
He has not been transfused since that time. It would be most helpful to: -
<<ANSWER>>phenotype his cells to determine which additional alloantibodies may be
produced
autoantibodies demonstrating blood group specificity in warm autoimmune hemolytic
anemia are associated more often with which blood group system? - <<ANSWER>>Rh
An antibody that causes in vitro hemolysis and reacts with the red cells of 3 out of 10
AHG-crossmatched donor units is most likely: - <<ANSWER>>anti-Le^a
,36, 37 ,38 pg - <<ANSWER>>A, B, D, B
in the process of identifying an antibody, the technologist observed 2+ reactions with 3
of the 10 cells in a panel after the immediate spin phase. There was no reactivity after
incubation at 37 oC and after the anti-human globulin test phase. The antibody most
likely is: - <<ANSWER>>anti-Le^a
Transfusion of Ch+ (Chido-positive) red cells to a patient with anti-Ch has been reported
to cause: - <<ANSWER>>no clinically significant red cell destruction
which characteristics are true of ALL 3 of the following antibodies: anti-Fy^a, anti-Jk^a,
and anti-K? - <<ANSWER>>detected at IAT phase and may cause hemolytic disease of
the fetus and newborn (HDFN) and transfusion reactions
38,39 - <<ANSWER>>C, B
which of the following test is most commonly used to detect antibodies attached to a
patient's red blood cells in vivo? - <<ANSWER>>direct antiglobulin
Anti-I inn cold agglutinin disease may cause a positive direct antiglobulin test (DAT)
because of: - <<ANSWER>>C3d bound to the red cells
a patient's antibody identification panel demonstrated anti-M. The antibody was most
reactive with homozygous M+ cells compared to heterozygous M+ cells. Which of the
following cells would demonstrate the strongest reaction? - <<ANSWER>>M+N-S-s+
in the direct antigloulin test, the antiglobulin reagent is used to: - <<ANSWER>>detect
preexisting antibodies on erythrocytes
the mechanism that best explains hemolytic anemia due to penicillin is: -
<<ANSWER>>drug-dependent antibodies reacting with drug-treated cells
Use of EDTA plasma prevents activation of the classical complement pathway by: -
<<ANSWER>>chelating Mg++ ions, which prevents assembly of C6chelating Ca++ions,
which prevents assembly of C1
the drug cephalosporin can cause a positive direct antiglobulin test due to modification
of the RBC membrane by the drug which is independent of antibody production. This
mechanism related to the drug cephalosporin is best described as: -
<<ANSWER>>nonimmunologic protein adsorption
During prenatal studies, a woman is noted to have a positive antibody screen and anti-
Kp^a is identified. What percentage of units will be compatible for this patient if
transfusion is necessary? - <<ANSWER>>>98%
the purpose of testing with anti-A,B is to detect: - <<ANSWER>>subgroups of A
, A group O, Rh-negative pregnant female has anti-Vel in her serum. If needed, how
might blood be provided for her infant? - <<ANSWER>>maternal donation
diagram - pg. 41, #260 - <<ANSWER>>B
while performing an antibody screen, a test reaction is suspected to be rouleaux. A
saline replacement test is performed and the reaction remains. What is the best
interpretation? - <<ANSWER>>original reaction was due to true agglutination
diagram - pg. 41, #262 - <<ANSWER>>A
Mixed field agglutination encountered in ABO grouping with no history of transfusion
would most likely be due to: - <<ANSWER>>A3 red cells
A patient demonstrates 4+ reactivity with all red cells tested and the autocontrol is
nonreactive. This high incidence antibody was suspected to be related to the P1PK
blood group system as the patient is the rare p phenotype. What antibody specificity
should be suspected? - <<ANSWER>>anti-PP1P^k
using the antigen typing results below, what is the patient's likely phenotype?
D+
C0
E+
c+
e+
f+
G + - <<ANSWER>>R2r
a patient received 2 units of RBC and had a delayed transfusion reaction.
Pretransfusion antibody screening records indicate no agglutination except after the
addition of IgG-sensitized cells. Repeat testing of the pretransfusion specimen detected
an antibody at the antiglobulin phase. What is the most likely explanation for the original
results? - <<ANSWER>>patient's serum was omitted from the original testing
In order to be a plateletpheresis donor, the platelet count must be at least: -
<<ANSWER>>150,000/ul
Prior to blood donation, the intended venipuncture site must be cleaned with a scrub
solution containing: - <<ANSWER>>Providone iodine
A donor who has just donated 2 units of Apheresis Red Blood Cells will be deferred
from further blood donation for a minimum of how many weeks? - <<ANSWER>>16
