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EEB 184 Midterm 2 Study Set Exam

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EEB 184 Midterm 2 Study
Set Exam
heterotopy - Answer evolutionary change of physical location of a developmental
process

heterochrony - Answer Evolutionary change in the timing or rate of an organism's
development.

heterotypy - Answer changes in the identity of the signaling molecule itself, rather than
where, how, and when it is expressed

heterometry - Answer change in amount of gene expression

dolphin - Answer Reduced hind limb (heterometry),

forelimb hyperphalangy (heterochrony),

forelimb webbing/flippers (heterotopy)

fins to limbs - Answer - limbs have "one part, two parts, a lot of parts"

- fins have both endochondral and dermal bones, limbs have only endochondral bones

BMP - Answer

gremlin - Answer

Fgf - Answer

cell survival - Answer

cell proliferation - Answer

ZPA - Answer

AER - Answer

Shh - Answer

pitx1 - Answer a hindlimb gene that stops being expressed in pigeons with hindlimb
feathers (they express Tbx5 instead) Example of Heterotypy

tbx5 - Answer not expressed in wt pigeons, but highly expressed in hindlimb feathered
pigeons. (tbx5 is normally expressed in forelimb and makes feather). Example of

, Heterotypy

endochondral bone - Answer any bone that develops in and replaces cartilage.

Human limbs are made of this bone

dermal bone - Answer 'Bone on skin': plates and scales. Forms directly as bone

Present in aquatic fins

one part/two part/lots of parts - Answer general structure of limb development

Tiktaalik - Answer "missing link" thought to be a transitional form between fish and
tetrapods

novel structure - Answer

autopod - Answer

homologue - Answer the existence of shared ancestry between a pair of structures, or
genes, in different taxa

second phase of Hox expression - Answer

hoxa13/hoxd13 - Answer

endochondral disc - Answer

cell migration - Answer

lepidotrichia - Answer

digits - Answer

digit reduction - Answer

jerboa - Answer

cow - Answer

congential malformation - Answer most common birth defects (3%), where 1/10 deal
with limbs (polydactyly, syndactylym and oligodactyly)

polydactyly - Answer extra fingers or toes

syndactyly - Answer Fusion of digits

oligodactyly - Answer missing digits

non-syndromic - Answer Only effects one region of the body (could be effected by a
mutation of the enhancer)

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