NR566 -Week 5 Study Guide-
Questions &
Answers(GRADED A)
Regarding osteoporosis, what are the two SERM drugs? - ANSWER -Tamoxifen
-Raloxifene
Tamoxifen is a good drug because it protects against osteoporosis, but what is it's downside? -
ANSWER -Higher risk for cancer
-Higher risk for blood clots
What is the the awesome benefit of Tamoxifen other than bone health? - ANSWER -Promotes good
blood lipid levels
What are the 3 main benefits of hormone therapy? - ANSWER -suppression of vasomotor symptoms
-prevention of urogenital atrophy
-prevention of osteoporosis and related fractures
Does urogenital atrophy and osteoporosis prevention sustain after withdrawal of HT? - ANSWER --
No, benefits will decline after HT withdrawal
Although HT therapy is great for bone loss prevention, what will happen when HT is stopped? -
ANSWER -bone mass rapidly decreases by approximately 12% ---Therapy must be life long--
Examples of progestins - ANSWER -Medroxyprogesterone acetate
-Norethindrone
,The nurse practitioner is considering adding progestin plus estrogen to his patient's med regimen.
The patient has HX of blood clotting disorders. What considerations must be dicussed? - ANSWER -
Increased risk for
--DVT
--Stroke
--MI
--PE
Susie just had her 65th birthday. She also has dementia and cardiovascular disease. Regarding
combination of estrogen/progestin, what is she at higher risk for ? - ANSWER -With these things,
she's at a higher risk for dementia
Tina has a mild risk of breast cancer. Is it a good idea for her to have estrogen/progestin combo? -
ANSWER -No, this combo of progestin/estrogen increases risk for breast cancer
The new doctor wants to prescribe progestins for a prepubertal child, his attendee says what? -
ANSWER -He screams "NO", those are not for prepubertal children.
A patient asks her doctor if progestin is okay while breast feeding. What does he say? - ANSWER -
Progestins while breastfeeding may cause neonatal jaundice.
What are the guidelines for tapering a patient off HT? - ANSWER -There are no firm guidelines!
What kind of symptoms may occur while tapering off HT? - ANSWER -Tapering of HT may cause
vasomotor symptoms.
For women on EPT, the progestin dosage should remain... - ANSWER -unchanged because lowering
the progestin dosage might permit estrogen to stimulate endometrial growth, thereby posing a risk
for endometrial hyperplasia.
What are some names of intravaginal inserts? - ANSWER -Imvexxy
-Vagifem
-Yuvafem
, What are some names of intravaginal creams? - ANSWER -Estrace vaginal
-Premarin Vaginal
What is the name of a vaginal ring used for local effects? - ANSWER -Estring
--treatment of vulval and vaginal atrophy associated with menopause
A patient has undiagnosed vaginal bleeding, should she be prescribed HT? - ANSWER -No, don't give
HT with undiagnosed vaginal bleeding
Julie has some blood clotting issues in his body. He has active thrombophlebitis & thromboembolic
disorders Should she use HT? - ANSWER -No, better not use HT with blood and clotting issues.
What is one thing that makes Raloxifene better than Tamoxifen? - ANSWER -Lower risk for cancer
What is the only drug approved for prevention and treatment of osteoporosis? - ANSWER -Duavee
(conjugated estrogens/bazedoxifene)
What drug prevents osteoporosis and vasomotor symptoms in postmenopausal women with a
uterus? - ANSWER -Duavee (conjugated estrogens/bazedoxifene)
Amy has active liver disease, would HT be okay? - ANSWER No, better not use HT with active liver
problems
Yolanda has active breast cancer. Should she receive HT? - ANSWER No, those with active breast
cancer should not receive HT!
What is the name of a vaginal ring used for systemic effects? - ANSWER -Femring
--(control of hot flashes and night sweats) as well as local effects (e.g., treatment of vulval and
vaginal atrophy)
What is the best treatment for genitourinary symptoms of menopause? - ANSWER -Estrogen is the
best treatment for these symptoms.
What are some symptoms of genitourinary symptoms of menopause? - ANSWER -dryness
Questions &
Answers(GRADED A)
Regarding osteoporosis, what are the two SERM drugs? - ANSWER -Tamoxifen
-Raloxifene
Tamoxifen is a good drug because it protects against osteoporosis, but what is it's downside? -
ANSWER -Higher risk for cancer
-Higher risk for blood clots
What is the the awesome benefit of Tamoxifen other than bone health? - ANSWER -Promotes good
blood lipid levels
What are the 3 main benefits of hormone therapy? - ANSWER -suppression of vasomotor symptoms
-prevention of urogenital atrophy
-prevention of osteoporosis and related fractures
Does urogenital atrophy and osteoporosis prevention sustain after withdrawal of HT? - ANSWER --
No, benefits will decline after HT withdrawal
Although HT therapy is great for bone loss prevention, what will happen when HT is stopped? -
ANSWER -bone mass rapidly decreases by approximately 12% ---Therapy must be life long--
Examples of progestins - ANSWER -Medroxyprogesterone acetate
-Norethindrone
,The nurse practitioner is considering adding progestin plus estrogen to his patient's med regimen.
The patient has HX of blood clotting disorders. What considerations must be dicussed? - ANSWER -
Increased risk for
--DVT
--Stroke
--MI
--PE
Susie just had her 65th birthday. She also has dementia and cardiovascular disease. Regarding
combination of estrogen/progestin, what is she at higher risk for ? - ANSWER -With these things,
she's at a higher risk for dementia
Tina has a mild risk of breast cancer. Is it a good idea for her to have estrogen/progestin combo? -
ANSWER -No, this combo of progestin/estrogen increases risk for breast cancer
The new doctor wants to prescribe progestins for a prepubertal child, his attendee says what? -
ANSWER -He screams "NO", those are not for prepubertal children.
A patient asks her doctor if progestin is okay while breast feeding. What does he say? - ANSWER -
Progestins while breastfeeding may cause neonatal jaundice.
What are the guidelines for tapering a patient off HT? - ANSWER -There are no firm guidelines!
What kind of symptoms may occur while tapering off HT? - ANSWER -Tapering of HT may cause
vasomotor symptoms.
For women on EPT, the progestin dosage should remain... - ANSWER -unchanged because lowering
the progestin dosage might permit estrogen to stimulate endometrial growth, thereby posing a risk
for endometrial hyperplasia.
What are some names of intravaginal inserts? - ANSWER -Imvexxy
-Vagifem
-Yuvafem
, What are some names of intravaginal creams? - ANSWER -Estrace vaginal
-Premarin Vaginal
What is the name of a vaginal ring used for local effects? - ANSWER -Estring
--treatment of vulval and vaginal atrophy associated with menopause
A patient has undiagnosed vaginal bleeding, should she be prescribed HT? - ANSWER -No, don't give
HT with undiagnosed vaginal bleeding
Julie has some blood clotting issues in his body. He has active thrombophlebitis & thromboembolic
disorders Should she use HT? - ANSWER -No, better not use HT with blood and clotting issues.
What is one thing that makes Raloxifene better than Tamoxifen? - ANSWER -Lower risk for cancer
What is the only drug approved for prevention and treatment of osteoporosis? - ANSWER -Duavee
(conjugated estrogens/bazedoxifene)
What drug prevents osteoporosis and vasomotor symptoms in postmenopausal women with a
uterus? - ANSWER -Duavee (conjugated estrogens/bazedoxifene)
Amy has active liver disease, would HT be okay? - ANSWER No, better not use HT with active liver
problems
Yolanda has active breast cancer. Should she receive HT? - ANSWER No, those with active breast
cancer should not receive HT!
What is the name of a vaginal ring used for systemic effects? - ANSWER -Femring
--(control of hot flashes and night sweats) as well as local effects (e.g., treatment of vulval and
vaginal atrophy)
What is the best treatment for genitourinary symptoms of menopause? - ANSWER -Estrogen is the
best treatment for these symptoms.
What are some symptoms of genitourinary symptoms of menopause? - ANSWER -dryness
