Pharmacology NR566 final
Correct 100%!
For treatment of existing osteoporosis, the dose of alendronate - ANSWER 10 mg/day or 70
mg/week
Initial dosage for bone less prevention alendronate and risedronate - ANSWER 5 mg/day or 35
mg/week
Testosterone replacement therapy - ANSWER Erythrocytosis is a risk; Hgb and Hct levels checked,
expect increase first 6 mths, unless Hgb level higher than 17.5 g/dL, Hct higher than 54%, or both
suggests overtreatment or occasionally abuse. IM happens more than transdermal. If the Hct is
greater than 54%, therapy is stopped until the Hct decreases to a safe level. The patient should also
be evaluated for hypoxia and sleep apnea. Restarting therapy at a reduced dose usually solves
problems.
For treatment of existing osteoporosis, the dose of risedronate - ANSWER 75 mg for 2 consecutive
days or 150 mg once a month
Alendronate (Fosamax) - ANSWER Therapy with 10 mg daily can increase bone density by up to 10%
after 3 years and can decrease vertebral and hip fractures by 50%
Testosterone replacement therapy - ANSWER risk of prostate cancer
Adults with vitamin B12 deficiency that is not pernicious anemia - ANSWER 1,000 mcg of oral
cobalamin are given until normal B12 levels are achieved—usually 6 to 12 weeks. In seriously ill
patients, both vitamin B12 and folic acid may need to be administered.
Who cannot get TRT - ANSWER breast cancer in a male patient, prostrate cancer, polycythemia vera,
increased calcium in the blood from cancer, diabetes, high cholesterol, overweight and high blood
pressure
BC contraindications - ANSWER Age >40 yr or Smoker <35 yr
, BMI >30 due to increased VTE risk
HTN or hyperlipidemia
First-degree relative with DVT/PE
Major surgery without prolonged immobilization
Superficial thrombophlebitis
SLE on immunosuppressive therapy or with severe thrombocytopenia
Rheumatoid arthritis Sickle cell disease
Estrogens in pregnancy - ANSWER Category X due to high rate of teratogenicity in male and female
offspring
Syhpilis treatment (early/primary/secondary) - ANSWER 1. Pen G 2.4m IM (adults), 50,000u/kg (kids)
2. doxycycline 100mg BID 14d
3. Tetracycline 500mg QID 14d
Syhpilis treatment (later) - ANSWER Pen G 2.4m IM (adults) weekly x 3 weeks
Gonorrhea treatment - ANSWER 1. Rocephin 250mg IM w/ Zithro 1000mg po
2. Rocephin 250mg IM w/ doxycycline 100mg BID 7d
3. Zithro 2g PO
Chlamydia treatment - ANSWER 1. Zithro 1G PO
2. Doxycycline 100mg BID 7d
3. Erythromycin 500mg QID 7d
chancroid tx - ANSWER 1. Zithro 1G po/Rocephin 250mg IM
Herpes treatment 1 and 2 - ANSWER acyclovir 400mg TID 7-10d
HPV tx - ANSWER podofilox 0.5% topically BID 3d
Correct 100%!
For treatment of existing osteoporosis, the dose of alendronate - ANSWER 10 mg/day or 70
mg/week
Initial dosage for bone less prevention alendronate and risedronate - ANSWER 5 mg/day or 35
mg/week
Testosterone replacement therapy - ANSWER Erythrocytosis is a risk; Hgb and Hct levels checked,
expect increase first 6 mths, unless Hgb level higher than 17.5 g/dL, Hct higher than 54%, or both
suggests overtreatment or occasionally abuse. IM happens more than transdermal. If the Hct is
greater than 54%, therapy is stopped until the Hct decreases to a safe level. The patient should also
be evaluated for hypoxia and sleep apnea. Restarting therapy at a reduced dose usually solves
problems.
For treatment of existing osteoporosis, the dose of risedronate - ANSWER 75 mg for 2 consecutive
days or 150 mg once a month
Alendronate (Fosamax) - ANSWER Therapy with 10 mg daily can increase bone density by up to 10%
after 3 years and can decrease vertebral and hip fractures by 50%
Testosterone replacement therapy - ANSWER risk of prostate cancer
Adults with vitamin B12 deficiency that is not pernicious anemia - ANSWER 1,000 mcg of oral
cobalamin are given until normal B12 levels are achieved—usually 6 to 12 weeks. In seriously ill
patients, both vitamin B12 and folic acid may need to be administered.
Who cannot get TRT - ANSWER breast cancer in a male patient, prostrate cancer, polycythemia vera,
increased calcium in the blood from cancer, diabetes, high cholesterol, overweight and high blood
pressure
BC contraindications - ANSWER Age >40 yr or Smoker <35 yr
, BMI >30 due to increased VTE risk
HTN or hyperlipidemia
First-degree relative with DVT/PE
Major surgery without prolonged immobilization
Superficial thrombophlebitis
SLE on immunosuppressive therapy or with severe thrombocytopenia
Rheumatoid arthritis Sickle cell disease
Estrogens in pregnancy - ANSWER Category X due to high rate of teratogenicity in male and female
offspring
Syhpilis treatment (early/primary/secondary) - ANSWER 1. Pen G 2.4m IM (adults), 50,000u/kg (kids)
2. doxycycline 100mg BID 14d
3. Tetracycline 500mg QID 14d
Syhpilis treatment (later) - ANSWER Pen G 2.4m IM (adults) weekly x 3 weeks
Gonorrhea treatment - ANSWER 1. Rocephin 250mg IM w/ Zithro 1000mg po
2. Rocephin 250mg IM w/ doxycycline 100mg BID 7d
3. Zithro 2g PO
Chlamydia treatment - ANSWER 1. Zithro 1G PO
2. Doxycycline 100mg BID 7d
3. Erythromycin 500mg QID 7d
chancroid tx - ANSWER 1. Zithro 1G po/Rocephin 250mg IM
Herpes treatment 1 and 2 - ANSWER acyclovir 400mg TID 7-10d
HPV tx - ANSWER podofilox 0.5% topically BID 3d
