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UST ABSN Pathopharmacology 1 Exam
Questions And Correct Revised Answers
A drug is any chemical that can affect living processes - answer✔✔How do you define the word
drug?
Pharmacology can be defined as the study of drugs and their interaction with living things -
answer✔✔Define pharmacology
study of effect of drugs in man (as compared to animals or comparative pharmacology -
answer✔✔Define clinical pharmacology
also known as therapeutics, pharmacotherapeutics emphasizes the disease state and its
characteristics including therapy for and use of drugs in prevention and treatment of condition -
answer✔✔what are pharmacotherapeutics?
Drugs used to destroy or eliminate pathogenic cells or organisms. The term is usually restricted
to anti-infectives and cancer chemotherapy. - answer✔✔what are chemotherapeutic agents?
Toxicology deals with the effects of drugs. Toxicity is measured through the Therapeutic Index. -
answer✔✔what is toxicology and how do we measure a drugs toxicity?
therapeutic index is a ratio that measures toxicity. The ratio is found by putting the dose *capable
of killing 50% of animals (LD50) over than required to acheive a beneficial effect in 50% of
animals (ED50).
In clinical practice the THERAPEUTIC INDEX is described as the ratio of the dose that causes
toxicity over the dose that provides therapeutic effect. - answer✔✔What is the therapeutic index?
Tolerance is the hyporeactivity that occurring from chronic exposure to a drug. Achievement of
the same effects of the drug requires larger and larger doses. - answer✔✔what is tolerance?
Cross tolerance may happen when tolerance occurs across drugs of the same class or across
drugs that have the same pharmacological effects - answer✔✔What is cross tolerance and how
does it occur?
, ©THEBRIGHTSTARS 2024
Tolerance to opioids, barbiturates, and alcohol - answer✔✔what are some examples of
neurological adaptation/ cellular tolerance to drugs?
metabolic drug tolerance occurs when the body has an increased rate of elimination of the drug. -
answer✔✔What is metabolic drug tolerance?
enzyme induction which occurs when there is an increased activity of enzymes (the drug
transport system) - answer✔✔what is the most common form of metabolic tolerance?
pharmacodynamic processes determine the nature and intensity of the response. It is essentially
the effect of the drug ON the body.
EX: Target Organ, receptors, proteins, physiological effect etc. - answer✔✔What is
pharmacodynamics?
Pharmacokinetic processes determine how much of an admin- istered dose gets to its sites of
action. There are four major pharmacokinetic processes: (1) drug absorption, (2) drug
distribution, (3) drug metabolism, and (4) drug excretion. *These processes can be thought of as
the impact of the body on drugs* - answer✔✔What is pharmacokinetics?
what are the four major pharmacokinetic processes?
Down regulation - answer✔✔what type of tolerance occurs when there is a decrease in the
number, or decrease in the sensitivity, of receptor sites?
betablockers - answer✔✔what kind of drugs block receptors?
Betablockers block receptors resulting in increased the sensitivity of receptors. This is known as
Up Regulation - answer✔✔The use of betablockers can also cause a change in the sensitivity of
receptors. What is this caused and how does it occur?
Tachyphylaxis is a tolerance that develops acutely with only a few doses of a drug -
answer✔✔Define the term tachyphylaxis?
Idiosyncrasy describes an unexpected, abnormal, or peculiar reaction to a drug. - answer✔✔what
is idiosyncrasy?
no, adverse effects can occur regardless of the dosage level - answer✔✔Is dosing a factor in
patients that experience idiosyncrasy?
side effect describes any action of the drug other than the intended therapeutic effects.
UST ABSN Pathopharmacology 1 Exam
Questions And Correct Revised Answers
A drug is any chemical that can affect living processes - answer✔✔How do you define the word
drug?
Pharmacology can be defined as the study of drugs and their interaction with living things -
answer✔✔Define pharmacology
study of effect of drugs in man (as compared to animals or comparative pharmacology -
answer✔✔Define clinical pharmacology
also known as therapeutics, pharmacotherapeutics emphasizes the disease state and its
characteristics including therapy for and use of drugs in prevention and treatment of condition -
answer✔✔what are pharmacotherapeutics?
Drugs used to destroy or eliminate pathogenic cells or organisms. The term is usually restricted
to anti-infectives and cancer chemotherapy. - answer✔✔what are chemotherapeutic agents?
Toxicology deals with the effects of drugs. Toxicity is measured through the Therapeutic Index. -
answer✔✔what is toxicology and how do we measure a drugs toxicity?
therapeutic index is a ratio that measures toxicity. The ratio is found by putting the dose *capable
of killing 50% of animals (LD50) over than required to acheive a beneficial effect in 50% of
animals (ED50).
In clinical practice the THERAPEUTIC INDEX is described as the ratio of the dose that causes
toxicity over the dose that provides therapeutic effect. - answer✔✔What is the therapeutic index?
Tolerance is the hyporeactivity that occurring from chronic exposure to a drug. Achievement of
the same effects of the drug requires larger and larger doses. - answer✔✔what is tolerance?
Cross tolerance may happen when tolerance occurs across drugs of the same class or across
drugs that have the same pharmacological effects - answer✔✔What is cross tolerance and how
does it occur?
, ©THEBRIGHTSTARS 2024
Tolerance to opioids, barbiturates, and alcohol - answer✔✔what are some examples of
neurological adaptation/ cellular tolerance to drugs?
metabolic drug tolerance occurs when the body has an increased rate of elimination of the drug. -
answer✔✔What is metabolic drug tolerance?
enzyme induction which occurs when there is an increased activity of enzymes (the drug
transport system) - answer✔✔what is the most common form of metabolic tolerance?
pharmacodynamic processes determine the nature and intensity of the response. It is essentially
the effect of the drug ON the body.
EX: Target Organ, receptors, proteins, physiological effect etc. - answer✔✔What is
pharmacodynamics?
Pharmacokinetic processes determine how much of an admin- istered dose gets to its sites of
action. There are four major pharmacokinetic processes: (1) drug absorption, (2) drug
distribution, (3) drug metabolism, and (4) drug excretion. *These processes can be thought of as
the impact of the body on drugs* - answer✔✔What is pharmacokinetics?
what are the four major pharmacokinetic processes?
Down regulation - answer✔✔what type of tolerance occurs when there is a decrease in the
number, or decrease in the sensitivity, of receptor sites?
betablockers - answer✔✔what kind of drugs block receptors?
Betablockers block receptors resulting in increased the sensitivity of receptors. This is known as
Up Regulation - answer✔✔The use of betablockers can also cause a change in the sensitivity of
receptors. What is this caused and how does it occur?
Tachyphylaxis is a tolerance that develops acutely with only a few doses of a drug -
answer✔✔Define the term tachyphylaxis?
Idiosyncrasy describes an unexpected, abnormal, or peculiar reaction to a drug. - answer✔✔what
is idiosyncrasy?
no, adverse effects can occur regardless of the dosage level - answer✔✔Is dosing a factor in
patients that experience idiosyncrasy?
side effect describes any action of the drug other than the intended therapeutic effects.
