Correct Answers
Meglitinide ✅Repaglinide (Prandin)
Lower blood glucose levels by stimulating the release of insulin from the beta cells of
the pancreas.
Common/serious adverse effects: hypoglycemia
Thiazolidinediones ✅Pioglitazone (actos)
Lower blood glucose levels by increasing the sensitivity of muscle and fat tissue to
insulin, allowing moe glucose to enter the cells in the presence of insulin for metabolism
Androgen/androderm ✅-short acting androgen agent
-testosterone topical gel
-used for male hypogonadism
-common adverse effect: gastric irritation
-serious adverse effects: electrolyte imbalance, edema, hypercalcemia, masculinization,
hepatotoxicity
Alendronate (Fosamax) ✅Bisphosphonste
Used in the treatment and prevention of osteoporosis in post menopausal women, men
and glucocorticoid-induced osteoporosis in both men and women with low BMD who are
receiving 7.5mg of prednisone
Zoledronic acid (Reclast) ✅Bisphosphonate
Treatment and prevention of osteoporosis in post menopausal women, men,
glucocorticoid-induced osteoporosis in both. Especially if prescribed >7.5mg of
prednisone for at least 12 months
Risedronate (Actonel) ✅Bisphosphonate
Treatment and prevention of osteoporosis in post menopausal women, men, and
glucocorticoid-induced osteoporosis in both
Bisphosphonates ✅Inhibit bone resorption by actions on osteoclasts.
Decreasing the rate of bone resorption leads to an indirect increase in BMD
Adverse effects: flu like symptoms, hypocalcemia, bone and joint pain, fatigue
Alpha-glucosidase inhibitors ✅Acarbose (Precose)
-antihyperglycemic agent
-enzyme inhibitors that inhibit pancreatic alpha-amylase and gastrointestinal alpha-
glucoside hydrolase enzymes used in the digestion of sugars. Results in delayed
glucose absorption and a lowering of postprandial hyperglycemia.
Side effects: abdominal pain, gas, bloating, diarrhea, mild rash