NR566 -Week 5 Study Guide-
Questions &
Answers(GRADED A+)
Regarding osteoporosis, what are the two SERM drugs? - ANSWER -Tamoxifen
-Raloxifene
Tamoxifen is a good drug because it protects against osteoporosis, but what is it's downside? -
ANSWER -Higher risk for cancer
-Higher risk for blood clots
What is the the awesome benefit of Tamoxifen other than bone health? - ANSWER -Promotes good
blood lipid levels
What are the 3 main benefits of hormone therapy? - ANSWER -suppression of vasomotor symptoms
-prevention of urogenital atrophy
-prevention of osteoporosis and related fractures
Does urogenital atrophy and osteoporosis prevention sustain after withdrawal of HT? - ANSWER --
No, benefits will decline after HT withdrawal
Although HT therapy is great for bone loss prevention, what will happen when HT is stopped? -
ANSWER -bone mass rapidly decreases by approximately 12% ---Therapy must be life long--
Examples of progestins - ANSWER -Medroxyprogesterone acetate
-Norethindrone
,A patient has undiagnosed vaginal bleeding, should she be prescribed HT? - ANSWER -No, don't give
HT with undiagnosed vaginal bleeding
Julie has some blood clotting issues in his body. He has active thrombophlebitis & thromboembolic
disorders Should she use HT? - ANSWER -No, better not use HT with blood and clotting issues.
What is one thing that makes Raloxifene better than Tamoxifen? - ANSWER -Lower risk for cancer
What is the only drug approved for prevention and treatment of osteoporosis? - ANSWER -Duavee
(conjugated estrogens/bazedoxifene)
What drug prevents osteoporosis and vasomotor symptoms in postmenopausal women with a
uterus? - ANSWER -Duavee (conjugated estrogens/bazedoxifene)
Amy has active liver disease, would HT be okay? - ANSWER No, better not use HT with active liver
problems
Yolanda has active breast cancer. Should she receive HT? - ANSWER No, those with active breast
cancer should not receive HT!
The nurse practitioner is considering adding progestin plus estrogen to his patient's med regimen.
The patient has HX of blood clotting disorders. What considerations must be dicussed? - ANSWER -
Increased risk for
--DVT
--Stroke
--MI
--PE
Susie just had her 65th birthday. She also has dementia and cardiovascular disease. Regarding
combination of estrogen/progestin, what is she at higher risk for ? - ANSWER -With these things,
she's at a higher risk for dementia
Tina has a mild risk of breast cancer. Is it a good idea for her to have estrogen/progestin combo? -
ANSWER -No, this combo of progestin/estrogen increases risk for breast cancer
, The new doctor wants to prescribe progestins for a prepubertal child, his attendee says what? -
ANSWER -He screams "NO", those are not for prepubertal children.
A patient asks her doctor if progestin is okay while breast feeding. What does he say? - ANSWER -
Progestins while breastfeeding may cause neonatal jaundice.
What are the guidelines for tapering a patient off HT? - ANSWER -There are no firm guidelines!
What kind of symptoms may occur while tapering off HT? - ANSWER -Tapering of HT may cause
vasomotor symptoms.
For women on EPT, the progestin dosage should remain... - ANSWER -unchanged because lowering
the progestin dosage might permit estrogen to stimulate endometrial growth, thereby posing a risk
for endometrial hyperplasia.
What are some names of intravaginal inserts? - ANSWER -Imvexxy
-Vagifem
-Yuvafem
What are some names of intravaginal creams? - ANSWER -Estrace vaginal
-Premarin Vaginal
What is the name of a vaginal ring used for local effects? - ANSWER -Estring
--treatment of vulval and vaginal atrophy associated with menopause
What is the name of a vaginal ring used for systemic effects? - ANSWER -Femring
--(control of hot flashes and night sweats) as well as local effects (e.g., treatment of vulval and
vaginal atrophy)
What is the best treatment for genitourinary symptoms of menopause? - ANSWER -Estrogen is the
best treatment for these symptoms.
What are some symptoms of genitourinary symptoms of menopause? - ANSWER -dryness
Questions &
Answers(GRADED A+)
Regarding osteoporosis, what are the two SERM drugs? - ANSWER -Tamoxifen
-Raloxifene
Tamoxifen is a good drug because it protects against osteoporosis, but what is it's downside? -
ANSWER -Higher risk for cancer
-Higher risk for blood clots
What is the the awesome benefit of Tamoxifen other than bone health? - ANSWER -Promotes good
blood lipid levels
What are the 3 main benefits of hormone therapy? - ANSWER -suppression of vasomotor symptoms
-prevention of urogenital atrophy
-prevention of osteoporosis and related fractures
Does urogenital atrophy and osteoporosis prevention sustain after withdrawal of HT? - ANSWER --
No, benefits will decline after HT withdrawal
Although HT therapy is great for bone loss prevention, what will happen when HT is stopped? -
ANSWER -bone mass rapidly decreases by approximately 12% ---Therapy must be life long--
Examples of progestins - ANSWER -Medroxyprogesterone acetate
-Norethindrone
,A patient has undiagnosed vaginal bleeding, should she be prescribed HT? - ANSWER -No, don't give
HT with undiagnosed vaginal bleeding
Julie has some blood clotting issues in his body. He has active thrombophlebitis & thromboembolic
disorders Should she use HT? - ANSWER -No, better not use HT with blood and clotting issues.
What is one thing that makes Raloxifene better than Tamoxifen? - ANSWER -Lower risk for cancer
What is the only drug approved for prevention and treatment of osteoporosis? - ANSWER -Duavee
(conjugated estrogens/bazedoxifene)
What drug prevents osteoporosis and vasomotor symptoms in postmenopausal women with a
uterus? - ANSWER -Duavee (conjugated estrogens/bazedoxifene)
Amy has active liver disease, would HT be okay? - ANSWER No, better not use HT with active liver
problems
Yolanda has active breast cancer. Should she receive HT? - ANSWER No, those with active breast
cancer should not receive HT!
The nurse practitioner is considering adding progestin plus estrogen to his patient's med regimen.
The patient has HX of blood clotting disorders. What considerations must be dicussed? - ANSWER -
Increased risk for
--DVT
--Stroke
--MI
--PE
Susie just had her 65th birthday. She also has dementia and cardiovascular disease. Regarding
combination of estrogen/progestin, what is she at higher risk for ? - ANSWER -With these things,
she's at a higher risk for dementia
Tina has a mild risk of breast cancer. Is it a good idea for her to have estrogen/progestin combo? -
ANSWER -No, this combo of progestin/estrogen increases risk for breast cancer
, The new doctor wants to prescribe progestins for a prepubertal child, his attendee says what? -
ANSWER -He screams "NO", those are not for prepubertal children.
A patient asks her doctor if progestin is okay while breast feeding. What does he say? - ANSWER -
Progestins while breastfeeding may cause neonatal jaundice.
What are the guidelines for tapering a patient off HT? - ANSWER -There are no firm guidelines!
What kind of symptoms may occur while tapering off HT? - ANSWER -Tapering of HT may cause
vasomotor symptoms.
For women on EPT, the progestin dosage should remain... - ANSWER -unchanged because lowering
the progestin dosage might permit estrogen to stimulate endometrial growth, thereby posing a risk
for endometrial hyperplasia.
What are some names of intravaginal inserts? - ANSWER -Imvexxy
-Vagifem
-Yuvafem
What are some names of intravaginal creams? - ANSWER -Estrace vaginal
-Premarin Vaginal
What is the name of a vaginal ring used for local effects? - ANSWER -Estring
--treatment of vulval and vaginal atrophy associated with menopause
What is the name of a vaginal ring used for systemic effects? - ANSWER -Femring
--(control of hot flashes and night sweats) as well as local effects (e.g., treatment of vulval and
vaginal atrophy)
What is the best treatment for genitourinary symptoms of menopause? - ANSWER -Estrogen is the
best treatment for these symptoms.
What are some symptoms of genitourinary symptoms of menopause? - ANSWER -dryness
