NR293 Pharmacology - Exam 1.pdf file:///C:/Users/HP/Desktop/SSSSSSS/NR293%20Pharmacology%2
NR293 Pharmacology - Exam 1
1. What is the main goal of the endocrine system?
Answer For PHYSIOLOGIC STABIL- ITY (HOMEOSTASIS)
- Every cell and organ in the body is influenced by this system
2. What are hormones?
Answer The "CHEMICAL LANGUAGE" of the endocrine system
- Natural substances
- Secreted into the bloodstream and travels through the blood to the site of action
3. Hypothalamus
Answer Part of the CNS
- MASTER
- THERMOSTAT
4. Pituitary Gland
Answer Has two lobes
- Anterior pituitary (adenohypohysis)
- Posterior pituitary (neurohypophysis)
1 of 70 8/30/2024, 3:32
,NR293 Pharmacology - Exam 1.pdf file:///C:/Users/HP/Desktop/SSSSSSS/NR293%20Pharmacology%2
They govern all bodily functions (hormones and negative feedback loop)
5. Negative Feedback Loop
Answer Activity of the endocrine system regulated by this system of surveillance and
signaling based on the body's needs
- Regulates hormone secretion
6. What are the anterior pituitary drugs?
Answer Cosyntopin Somatopin
Octreotide
7. What are the posterior pituitary drugs?
Answer Vasopressin Desmopressin
8. Cosyntopin (Cortosyn)
Answer STIMULATES RELEASE OF CORTISOL FROM THE ADRENAL CORTEX
- Anti-inflammatory
- DIAGNOSIS OF ADRENOCORTICAL INSUFFICIENCY
- Wasting associated with human immunodeficiency virus infection
- Promotes renal retention of SODIUM, WHICH CAN RESULT IN EDEMA AND
HYPERTENSION
9. Somatropin & Somatem
2 of 70 8/30/2024, 3:32
,NR293 Pharmacology - Exam 1.pdf file:///C:/Users/HP/Desktop/SSSSSSS/NR293%20Pharmacology%2
Answer Recombinantly made GROWTH HORMONE (GH)
- Stimulates skeletal growth in patients with deficient GH, such as HYPOPITUITARY DWARFISM
10. Octreotide (Sandostatin)
Answer CARCINOID TUMORS SECRETE VIP (vasoactive intestinal polypeptide)
- VIP causes PROFUSE, WATERY DIARRHEA
- Octreotide reduces diarrhea, flushing, and life-threatening HYPOTENSION that may occur
with a CARCINOID CRISIS
11. Vasopressin & Desmopressin
Answer Mimic the action of ANTIDIURETIC HOR- MONE
3 of 70 8/30/2024, 3:32
,NR293 Pharmacology - Exam 1.pdf file:///C:/Users/HP/Desktop/SSSSSSS/NR293%20Pharmacology%2
- Increase WATER REABSORPTION in the distal tubules and collecting ducts of nephrons that
concentrate urine
- REDUCES WATER EXCRETION by up to 90%
- Used in treatment with DIABETES INSIPIDUS
12. Indications for Vasopressin
Answer ADH - Diabetes Insipidus
- POTENT VASOCONSTRICTOR
- HYPOTENSIVE EMERGENCIES (Vasodilatory Shock - Septic Shock)
- ADVANCES CARDIAC LIFE SUPPORT (ACLS) - PULSELESS CARDIAC AR- REST
- Used to STOP BLEEDING OF ESOPHAGEAL VARICES
13. Indications for Desmopressin
Answer DDVAP
- Dose-dependent increase in the plasma levels of
- Factor VIII (antihemophilic factor)
- Von Willebrand factor
- Tissue plasminogen activator (HELPS WITH CLOTTING)
- Management of NOCTURNAL ENURESIS
4 of 70 8/30/2024, 3:32
NR293 Pharmacology - Exam 1
1. What is the main goal of the endocrine system?
Answer For PHYSIOLOGIC STABIL- ITY (HOMEOSTASIS)
- Every cell and organ in the body is influenced by this system
2. What are hormones?
Answer The "CHEMICAL LANGUAGE" of the endocrine system
- Natural substances
- Secreted into the bloodstream and travels through the blood to the site of action
3. Hypothalamus
Answer Part of the CNS
- MASTER
- THERMOSTAT
4. Pituitary Gland
Answer Has two lobes
- Anterior pituitary (adenohypohysis)
- Posterior pituitary (neurohypophysis)
1 of 70 8/30/2024, 3:32
,NR293 Pharmacology - Exam 1.pdf file:///C:/Users/HP/Desktop/SSSSSSS/NR293%20Pharmacology%2
They govern all bodily functions (hormones and negative feedback loop)
5. Negative Feedback Loop
Answer Activity of the endocrine system regulated by this system of surveillance and
signaling based on the body's needs
- Regulates hormone secretion
6. What are the anterior pituitary drugs?
Answer Cosyntopin Somatopin
Octreotide
7. What are the posterior pituitary drugs?
Answer Vasopressin Desmopressin
8. Cosyntopin (Cortosyn)
Answer STIMULATES RELEASE OF CORTISOL FROM THE ADRENAL CORTEX
- Anti-inflammatory
- DIAGNOSIS OF ADRENOCORTICAL INSUFFICIENCY
- Wasting associated with human immunodeficiency virus infection
- Promotes renal retention of SODIUM, WHICH CAN RESULT IN EDEMA AND
HYPERTENSION
9. Somatropin & Somatem
2 of 70 8/30/2024, 3:32
,NR293 Pharmacology - Exam 1.pdf file:///C:/Users/HP/Desktop/SSSSSSS/NR293%20Pharmacology%2
Answer Recombinantly made GROWTH HORMONE (GH)
- Stimulates skeletal growth in patients with deficient GH, such as HYPOPITUITARY DWARFISM
10. Octreotide (Sandostatin)
Answer CARCINOID TUMORS SECRETE VIP (vasoactive intestinal polypeptide)
- VIP causes PROFUSE, WATERY DIARRHEA
- Octreotide reduces diarrhea, flushing, and life-threatening HYPOTENSION that may occur
with a CARCINOID CRISIS
11. Vasopressin & Desmopressin
Answer Mimic the action of ANTIDIURETIC HOR- MONE
3 of 70 8/30/2024, 3:32
,NR293 Pharmacology - Exam 1.pdf file:///C:/Users/HP/Desktop/SSSSSSS/NR293%20Pharmacology%2
- Increase WATER REABSORPTION in the distal tubules and collecting ducts of nephrons that
concentrate urine
- REDUCES WATER EXCRETION by up to 90%
- Used in treatment with DIABETES INSIPIDUS
12. Indications for Vasopressin
Answer ADH - Diabetes Insipidus
- POTENT VASOCONSTRICTOR
- HYPOTENSIVE EMERGENCIES (Vasodilatory Shock - Septic Shock)
- ADVANCES CARDIAC LIFE SUPPORT (ACLS) - PULSELESS CARDIAC AR- REST
- Used to STOP BLEEDING OF ESOPHAGEAL VARICES
13. Indications for Desmopressin
Answer DDVAP
- Dose-dependent increase in the plasma levels of
- Factor VIII (antihemophilic factor)
- Von Willebrand factor
- Tissue plasminogen activator (HELPS WITH CLOTTING)
- Management of NOCTURNAL ENURESIS
4 of 70 8/30/2024, 3:32
