NUR 545 Final Exam Guide With
Complete Solution
Drug interaction for penicillin? - ANSWER o Aminoglycosides- don't mix
penicillin with this drug. Penicillin deactivates aminoglycoside.
MOA for penicillin? - ANSWER o disrupts bacterial cells wall which leads to
cell death
Adverse effect of penicillin? - ANSWER o anaphylactic reaction (s/s: SOB,
rash, angioedema). Give epinephrine when this occurs.
High-risk patients for penicillin - ANSWER o The elderly or renal impairment
(reduce the dose)
What's the cross-reactivity with penicillin (beta lactam ring)? - ANSWER o
Cephalosporins- a small percentage of people who get a reaction with
penicillin will have a reaction when taking cephalosporins.
High risk population for gentamicin? - ANSWER patients w/renal impairment
Major adverse effects of gentamicin? - ANSWER Ototoxicity, nephrotoxicity.
gentamicin s/s of ototoxicity (HHTNV)? - ANSWER -tinnitus, hearing loss,
vertigo, headache, nausea. (HHTNV)
Gentamicin- first sign of ototoxicity? - ANSWER h/a
What's the neuromuscular blockade reversal agent for gentamicin? -
ANSWER IV calcium gluconate.
Therapeutic use for Fosfomycin? - ANSWER UTI-single dose
, Drug interaction for Cefotetan? - ANSWER o ALCOHOL causes disulfiram
reaction (flushing, palpitation, nausea).
Adverse effect of Vancomycin? - ANSWER Red Man Syndrome, red from the
torso up, V/S- hypotension, tachycardia. This occurs when an infusion is
given too quickly.
First-line drug use for tetracycline? - ANSWER o Rickettsia disease,
Chlamydia, Lyme disease.
Adverse effects of tetracycline? - ANSWER -Long bone suppression-
suppresses growth in premature infants
-teeth discoloration (for children under the age of eight)
-fetal harm in pregnant women & breast-feeding women (they must avoid
this drug)
Food interaction with tetracycline? - ANSWER milk products suppress
absorption
Adverse effect of trimethoprim/sulfamethoxazole (Bactrim)? - ANSWER o
Kernicterus in neonates- elevated bilirubin which can lead to cerebral palsy,
hearing loss, and effect the teeth.
For a patient taking trimethoprim/sulfamethoxazole (Bactrim), what
statement indicates that symptoms are not improving? - ANSWER I'm having
flank pain.
Complete Solution
Drug interaction for penicillin? - ANSWER o Aminoglycosides- don't mix
penicillin with this drug. Penicillin deactivates aminoglycoside.
MOA for penicillin? - ANSWER o disrupts bacterial cells wall which leads to
cell death
Adverse effect of penicillin? - ANSWER o anaphylactic reaction (s/s: SOB,
rash, angioedema). Give epinephrine when this occurs.
High-risk patients for penicillin - ANSWER o The elderly or renal impairment
(reduce the dose)
What's the cross-reactivity with penicillin (beta lactam ring)? - ANSWER o
Cephalosporins- a small percentage of people who get a reaction with
penicillin will have a reaction when taking cephalosporins.
High risk population for gentamicin? - ANSWER patients w/renal impairment
Major adverse effects of gentamicin? - ANSWER Ototoxicity, nephrotoxicity.
gentamicin s/s of ototoxicity (HHTNV)? - ANSWER -tinnitus, hearing loss,
vertigo, headache, nausea. (HHTNV)
Gentamicin- first sign of ototoxicity? - ANSWER h/a
What's the neuromuscular blockade reversal agent for gentamicin? -
ANSWER IV calcium gluconate.
Therapeutic use for Fosfomycin? - ANSWER UTI-single dose
, Drug interaction for Cefotetan? - ANSWER o ALCOHOL causes disulfiram
reaction (flushing, palpitation, nausea).
Adverse effect of Vancomycin? - ANSWER Red Man Syndrome, red from the
torso up, V/S- hypotension, tachycardia. This occurs when an infusion is
given too quickly.
First-line drug use for tetracycline? - ANSWER o Rickettsia disease,
Chlamydia, Lyme disease.
Adverse effects of tetracycline? - ANSWER -Long bone suppression-
suppresses growth in premature infants
-teeth discoloration (for children under the age of eight)
-fetal harm in pregnant women & breast-feeding women (they must avoid
this drug)
Food interaction with tetracycline? - ANSWER milk products suppress
absorption
Adverse effect of trimethoprim/sulfamethoxazole (Bactrim)? - ANSWER o
Kernicterus in neonates- elevated bilirubin which can lead to cerebral palsy,
hearing loss, and effect the teeth.
For a patient taking trimethoprim/sulfamethoxazole (Bactrim), what
statement indicates that symptoms are not improving? - ANSWER I'm having
flank pain.
