BIOD322
Neuroscience Research Methods
FINAL ASSESSMENT GUIDE
© Portage 2024/2025
,1. Which of the following techniques is primarily used to measure
the electrical activity of neurons?
a) fMRI
b) EEG
c) PET
d) DTI
Answer: b) EEG
Rationale: EEG (Electroencephalography) is used to measure
electrical activity in the brain by recording from the scalp. It is
widely used in neuroscience research for studying brain functions
and disorders.
2. In optogenetics, which type of protein is typically used to
control neuronal activity with light?
© Portage 2024/2025
, a) Channelrhodopsins
b) Hemoglobin
c) Cyclins
d) Tubulins
Answer: a) Channelrhodopsins
Rationale: Channelrhodopsins are light-sensitive proteins that
can be used to activate or inhibit neurons in optogenetics research.
3. What is the primary advantage of using two-photon microscopy
over traditional confocal microscopy in brain research?
a) Higher temporal resolution
b) Greater tissue penetration
© Portage 2024/2025
, c) Lower cost
d) Better color differentiation
Answer: b) Greater tissue penetration
Rationale: Two-photon microscopy allows deeper imaging into
biological tissues with minimal damage, which is crucial for
studying brain structures.
4. Which statistical model is most appropriate for analyzing the
firing rates of neurons in a time-series data set?
a) Linear Regression
b) Poisson Regression
c) Chi-Square Test
d) ANOVA
© Portage 2024/2025
Neuroscience Research Methods
FINAL ASSESSMENT GUIDE
© Portage 2024/2025
,1. Which of the following techniques is primarily used to measure
the electrical activity of neurons?
a) fMRI
b) EEG
c) PET
d) DTI
Answer: b) EEG
Rationale: EEG (Electroencephalography) is used to measure
electrical activity in the brain by recording from the scalp. It is
widely used in neuroscience research for studying brain functions
and disorders.
2. In optogenetics, which type of protein is typically used to
control neuronal activity with light?
© Portage 2024/2025
, a) Channelrhodopsins
b) Hemoglobin
c) Cyclins
d) Tubulins
Answer: a) Channelrhodopsins
Rationale: Channelrhodopsins are light-sensitive proteins that
can be used to activate or inhibit neurons in optogenetics research.
3. What is the primary advantage of using two-photon microscopy
over traditional confocal microscopy in brain research?
a) Higher temporal resolution
b) Greater tissue penetration
© Portage 2024/2025
, c) Lower cost
d) Better color differentiation
Answer: b) Greater tissue penetration
Rationale: Two-photon microscopy allows deeper imaging into
biological tissues with minimal damage, which is crucial for
studying brain structures.
4. Which statistical model is most appropriate for analyzing the
firing rates of neurons in a time-series data set?
a) Linear Regression
b) Poisson Regression
c) Chi-Square Test
d) ANOVA
© Portage 2024/2025
