NURS 4600 Week 3 Test With
Complete Solution
IMMUNIZATIONS - ANSWER IMMUNIZATIONS
active vs passive immunity - ANSWER Active = individual has memory cells -
can make their own antibodies & provides long term immunity
Passive = person given antibodies, these work then die, no long term
immunity, no memory cells.
attenuated - ANSWER weakened, thinned, decreased
toxoids - ANSWER inactivated exotoxins used in vaccines. usually boosters
required
Where are the most common thrombosis locations? - ANSWER legs, lungs,
heart, brain
IVIG - ANSWER intravenous immunoglobulin. ppl get them once a month
side effects of immunoglobulins - ANSWER thrombosis
contraindications for immunization use - ANSWER During febrile illnesses
During immunosuppressive drug therapy
During immunodeficient states
Leukemia
Lymphoma
,Generalized malignancy
Pregnancy
ACIP - ANSWER CDC Advisory Committee on Immunization Practices
What are the sources of information on immunizations? - ANSWER CDC ACIP
American Academy of Pediatrics (AAP)
American Academy of Family Physicians (AAFP)
Local health department
mild vs serious reactions for vaccines - ANSWER Mild rxn - arm soreness,
fever, cold symptoms
Serious rxn - allergic rxn via anaphylaxis, pruritus, obscure GI symptoms via
vomiting and diarrhea
GVHD - ANSWER graft-versus-host disease
complication that occurs following a stem cell or bone marrow transplant in
which the transplant produces antibodies against recipient's organs that can
be severe enough to cause death
Acute organ rejection - ANSWER - Immediate failure of that organ
- Flu-like symptoms (fever, chills, malaise)
- Immediate biopsy of the transplanted organ is usually warranted as soon as
, possible.
What lab values will you look at for organ transplant? - ANSWER WBC less
than 5k means immunosupressed
Liver is AST and ALT
Kidney is creatinine and BUN
vasculitis lesion - ANSWER intense inflammation, vessel wall necrosis
chronic reaction to organ transplant - ANSWER Occur after months or years
of normal function
Characteristics include
Progressive failure of transplanted organ
Fibrosis of blood vessels
Mycophenolate mofetil - ANSWER CellCept brand name
Acts in B and T cells to inhibit inosine monophosphate (IMP)
dehydrogenase-->decreased GMP in de novo purine synth-->decreased DNA
synth in B and T cells-->decreased prolif of B and T cells
Complete Solution
IMMUNIZATIONS - ANSWER IMMUNIZATIONS
active vs passive immunity - ANSWER Active = individual has memory cells -
can make their own antibodies & provides long term immunity
Passive = person given antibodies, these work then die, no long term
immunity, no memory cells.
attenuated - ANSWER weakened, thinned, decreased
toxoids - ANSWER inactivated exotoxins used in vaccines. usually boosters
required
Where are the most common thrombosis locations? - ANSWER legs, lungs,
heart, brain
IVIG - ANSWER intravenous immunoglobulin. ppl get them once a month
side effects of immunoglobulins - ANSWER thrombosis
contraindications for immunization use - ANSWER During febrile illnesses
During immunosuppressive drug therapy
During immunodeficient states
Leukemia
Lymphoma
,Generalized malignancy
Pregnancy
ACIP - ANSWER CDC Advisory Committee on Immunization Practices
What are the sources of information on immunizations? - ANSWER CDC ACIP
American Academy of Pediatrics (AAP)
American Academy of Family Physicians (AAFP)
Local health department
mild vs serious reactions for vaccines - ANSWER Mild rxn - arm soreness,
fever, cold symptoms
Serious rxn - allergic rxn via anaphylaxis, pruritus, obscure GI symptoms via
vomiting and diarrhea
GVHD - ANSWER graft-versus-host disease
complication that occurs following a stem cell or bone marrow transplant in
which the transplant produces antibodies against recipient's organs that can
be severe enough to cause death
Acute organ rejection - ANSWER - Immediate failure of that organ
- Flu-like symptoms (fever, chills, malaise)
- Immediate biopsy of the transplanted organ is usually warranted as soon as
, possible.
What lab values will you look at for organ transplant? - ANSWER WBC less
than 5k means immunosupressed
Liver is AST and ALT
Kidney is creatinine and BUN
vasculitis lesion - ANSWER intense inflammation, vessel wall necrosis
chronic reaction to organ transplant - ANSWER Occur after months or years
of normal function
Characteristics include
Progressive failure of transplanted organ
Fibrosis of blood vessels
Mycophenolate mofetil - ANSWER CellCept brand name
Acts in B and T cells to inhibit inosine monophosphate (IMP)
dehydrogenase-->decreased GMP in de novo purine synth-->decreased DNA
synth in B and T cells-->decreased prolif of B and T cells
