Chapter 12 beckers world of the cell
Adaptor proteins are sometimes called assembly proteins, what do they need - ANSWER-They take
energy ATP or GTP for binding of complexes to the membrane
Complexes traveling by transport vesicles to a different region of the plasma membrane - ANSWER-
transcytosis
COPI - ANSWER-involved in retrograde transport from the golgi back to the ER
COPII - ANSWER-anterograde transport from the ER to the Golgi
Core oligosaccharides commonly have what? - ANSWER-two units of N-acetylglucosamine, nine
mannose units, and three glucose units
Drug detoxification involves - ANSWER-Hydroxylation
Endocytosis - ANSWER-Cell eats external materials
Endoplasmic Reticulum - ANSWER-A continuous network of flattened sacs, tubules, and vesicles
ER Cisternae - ANSWER-membrane bound sacs in ER
ER Lumen - ANSWER-space inside the cisternae
Exocytosis - ANSWER-vesicular transport or secretory vesicles release contents outside of cell
How are phospholipids transferred? - ANSWER-by phospholipid translocators (flippases)
How do proteins and lipids leave the Golgi complex? - ANSWER-Transport vesicles from the trans-
golgi network
How do proteins know where to go? - ANSWER-Each protein has a tag for a specific vesicle
How do steroids differ? - ANSWER-Number of carbon chains and hydroxyl groups
How is hydroxylation catalyzed - ANSWER-by cytochrome-P450 (for drug detoxification)
How phospholipids move from the ER to other organelles? - ANSWER-By phospholipid exchange
proteins
NSF and SNAPs - ANSWER-release of the snares of the donor and target membranes
phagocytosis - ANSWER-cellular eating of large particles
pinocytosis - ANSWER-cellular drinking
Rough ER is the site for - ANSWER-Initial steps of glycoproteins, folding of polypeptides, recognition
and removal of misfoled protiens, and assembly of multimeric protein complexes
SNARE hypothesis - ANSWER-the sorting and targeting of vesicles involves two families of SNARE
proteins (SNAP receptor)
Target-SNAP receptors are found on - ANSWER-target membranes
Types of ligand-receptor complexes traveling - ANSWER--complexes carried to a lysosome for
degradation
-complexes are carried to the TGN where they enter a variety of pathways
-complexes can also travel by transport vesicles to a different region of the plasma membrane
Adaptor proteins are sometimes called assembly proteins, what do they need - ANSWER-They take
energy ATP or GTP for binding of complexes to the membrane
Complexes traveling by transport vesicles to a different region of the plasma membrane - ANSWER-
transcytosis
COPI - ANSWER-involved in retrograde transport from the golgi back to the ER
COPII - ANSWER-anterograde transport from the ER to the Golgi
Core oligosaccharides commonly have what? - ANSWER-two units of N-acetylglucosamine, nine
mannose units, and three glucose units
Drug detoxification involves - ANSWER-Hydroxylation
Endocytosis - ANSWER-Cell eats external materials
Endoplasmic Reticulum - ANSWER-A continuous network of flattened sacs, tubules, and vesicles
ER Cisternae - ANSWER-membrane bound sacs in ER
ER Lumen - ANSWER-space inside the cisternae
Exocytosis - ANSWER-vesicular transport or secretory vesicles release contents outside of cell
How are phospholipids transferred? - ANSWER-by phospholipid translocators (flippases)
How do proteins and lipids leave the Golgi complex? - ANSWER-Transport vesicles from the trans-
golgi network
How do proteins know where to go? - ANSWER-Each protein has a tag for a specific vesicle
How do steroids differ? - ANSWER-Number of carbon chains and hydroxyl groups
How is hydroxylation catalyzed - ANSWER-by cytochrome-P450 (for drug detoxification)
How phospholipids move from the ER to other organelles? - ANSWER-By phospholipid exchange
proteins
NSF and SNAPs - ANSWER-release of the snares of the donor and target membranes
phagocytosis - ANSWER-cellular eating of large particles
pinocytosis - ANSWER-cellular drinking
Rough ER is the site for - ANSWER-Initial steps of glycoproteins, folding of polypeptides, recognition
and removal of misfoled protiens, and assembly of multimeric protein complexes
SNARE hypothesis - ANSWER-the sorting and targeting of vesicles involves two families of SNARE
proteins (SNAP receptor)
Target-SNAP receptors are found on - ANSWER-target membranes
Types of ligand-receptor complexes traveling - ANSWER--complexes carried to a lysosome for
degradation
-complexes are carried to the TGN where they enter a variety of pathways
-complexes can also travel by transport vesicles to a different region of the plasma membrane
