NURS 752
Clinical Psychopharmacology
COMPLETE MIDTERM EXAM
REVIEW
©LU 2024/2025
,1. Which neurotransmitter is primarily associated with the
mechanism of action of typical antipsychotics?
- A) Norepinephrine
- B) Dopamine
- C) Serotonin
- D) Acetylcholine
Answer: B) Dopamine
Rationale: Typical antipsychotics primarily block dopamine
D2 receptors, which reduces psychotic symptoms.
2. SSRIs (Selective Serotonin Reuptake Inhibitors) primarily exert
their effects by:
- A) Inhibiting serotonin synthesis
- B) Blocking serotonin receptors
- C) Preventing the reuptake of serotonin
- D) Increasing norepinephrine levels
Answer: C) Preventing the reuptake of serotonin
Rationale: SSRIs block the reuptake of serotonin at the
synaptic cleft, leading to increased serotonin levels.
©LU 2024/2025
, 3. Which of the following is a common side effect of
benzodiazepines?
- A) Insomnia
- B) Excessive sleepiness
- C) Hypertension
- D) Hyperactivity
Answer: B) Excessive sleepiness
Rationale: Benzodiazepines are central nervous system
depressants that can cause sedation and drowsiness.
4. Which pharmacodynamic effect might result from the co-
administration of an SSRI and a monoamine oxidase inhibitor
(MAOI)?
- A) Increased sedation
- B) Serotonin syndrome
- C) Decreased efficacy of the SSRI
- D) Enhanced metabolism of the MAOI
Answer: B) Serotonin syndrome
Rationale: Co-administration can lead to excessive serotonin
levels, resulting in serotonin syndrome, characterized by confusion,
hyperreflexia, and autonomic instability.
©LU 2024/2025
Clinical Psychopharmacology
COMPLETE MIDTERM EXAM
REVIEW
©LU 2024/2025
,1. Which neurotransmitter is primarily associated with the
mechanism of action of typical antipsychotics?
- A) Norepinephrine
- B) Dopamine
- C) Serotonin
- D) Acetylcholine
Answer: B) Dopamine
Rationale: Typical antipsychotics primarily block dopamine
D2 receptors, which reduces psychotic symptoms.
2. SSRIs (Selective Serotonin Reuptake Inhibitors) primarily exert
their effects by:
- A) Inhibiting serotonin synthesis
- B) Blocking serotonin receptors
- C) Preventing the reuptake of serotonin
- D) Increasing norepinephrine levels
Answer: C) Preventing the reuptake of serotonin
Rationale: SSRIs block the reuptake of serotonin at the
synaptic cleft, leading to increased serotonin levels.
©LU 2024/2025
, 3. Which of the following is a common side effect of
benzodiazepines?
- A) Insomnia
- B) Excessive sleepiness
- C) Hypertension
- D) Hyperactivity
Answer: B) Excessive sleepiness
Rationale: Benzodiazepines are central nervous system
depressants that can cause sedation and drowsiness.
4. Which pharmacodynamic effect might result from the co-
administration of an SSRI and a monoamine oxidase inhibitor
(MAOI)?
- A) Increased sedation
- B) Serotonin syndrome
- C) Decreased efficacy of the SSRI
- D) Enhanced metabolism of the MAOI
Answer: B) Serotonin syndrome
Rationale: Co-administration can lead to excessive serotonin
levels, resulting in serotonin syndrome, characterized by confusion,
hyperreflexia, and autonomic instability.
©LU 2024/2025