ADVANCED PHARMACOLOGY FINAL -
PRACTICE QUIZ QUESTIONS AND
ANSWERS
Escitalopramsmayscausesserious,spotentiallysfatalsreactionsswhensusedswiths___________
____.s(selectsallsthatsapply)s-sans✔✔Duloxetine,samitriptilyne,ssertraline,sSt.sJohn'ssWorts
Mixingstwosserotoninsagentsscanscausesserotoninssyndrome.
Thestherapeuticseffectssofsimipraminesdevelopsovers_____________.s-
sans✔✔Severalsweeks
ThesFDA-approvedsindicationssforsfluoxetinesinclude:s(selectsallsthatsapply)s-
sans✔✔Obsessivescompulsivesdisorder,smajorsdepressivesdisorder,sbulimiasnervosa
Takingsfoodswithsbuspironesalterssabsorption.s-sans✔✔False
Maysbestakenswithsfoodstosminimizesgastricsirritation
Venlafaxinesissextensivelysmetabolizedsonsfirstspasssthroughsthes___________.s-
sans✔✔Liver
Signssandssymptomssofslithiumstoxicitysinclude:s(selectsallsthatsapply)s-
sans✔✔Slurredsspeech,sdrowsiness
ValproatesacidshassFDA-approvedsindicationssfor:s(selectsallsthatsapply)s-
sans✔✔Acutesmania,ssimplesandscomplexsabsencesseizures,spreventionsof smigraineshead
aches
Atomoxetinesselectivelys____________sthespresynapticsreuptakesofsnorepinephrinesresult
ingsinsa(n)s________________sattentionsspan.s-sans✔✔Inhibits,simproved
Phenelzinesdoessnotsneedstosbesdiscontinuedsseveralsdayssbeforeselectivessurgerysthatsre
quiressanesthesia.s-sans✔✔False
Bupropionscansbesusedsforssmokingscessation.s-sans✔✔True
Methylphenidatesissnotseffectivesforsnarcolepticspatients.s-sans✔✔False
Clozapinesmayscause:s(selectsallsthatsapply)s-
sans✔✔Syncope,sorthostaticshypotension,scardiacsarrests
,Causessbradycardiaswhichscouldsleadstossyncopesandscardiacsarrest
Administeringsrisperidoneswithslevodopasisscontraindicated.s-sans✔✔Trues
Itsdecreasesstheseffectssofslevodopa
Thes___________sformsofsziprasidonesissfrequentlysusedsforscontrolsofsacutelysagitatedspat
ients.s-sans✔✔Intramusculars(IM)
Anticonvulsantssaresfrequentlysusedsassmoodsstabilizerssforsthestreatmentsofsmaniasandsbi
polarsspectrumsdisorderssbecausesthey:s-sans✔✔Reducessynapticskindling
Aspatientswassstartedsonsfluoxetinesforsdepressions3sdayssago.sShesnowscomplainssthatsits"
doesn'tshelp"sandsrefusesstostakesit.sUnderstandingsthespsychopharmacology,sthesnurse'ss
bestsfirstsactionsissto:s-
sans✔✔Discussswithsthespatientsthatsthesestypessofsmedicationssoftenstakesseveralsweekss
beforesseeingsthesresults.
Whichsofsthesfollowingsissascommonssideseffectsofsbothsfirst-sandssecond-
generationsantipsychoticsdrugs?s(selectsallsthatsapply)s-
sans✔✔Extrapyramidalssideseffectsssuchsasspseudo-
parkinsonismsorsacutesdystonia,sneurolepticsmalignantssyndrome,sexcessivessedation
Asmalespatientswhosisstakingsthessecond-
generationsantipsychoticsreportsstosthesnursesthatsheshassobservedsasclearsfluidsleakingsfro
mshissrightsnipplesforsthespastsmonth.sThesnurse'ssbestsinitialsinterventionsis:s-
sans✔✔Informsthespatientsthatsthisscouldsbesassideseffectsofsthesmedication
Thesphysiciansdiscussessthesappropriatenesssofsprescribingsasserotonin/norepinephrinesre
uptakesinhibitors(SNRI)sforsaspatient.sWhichsofsthesfollowingsmedicationssaresinsthisscategor
y?s-sans✔✔Venlafaxinesandsduloxetine
Aspatientshassbeensprescribedsasselectivesserotoninsreuptakesinhibitors(SSRI)sforsdepressi
on.sThesnursesshouldscounselsthespatientsaboutswhichsofsthesfollowingspossiblessideseffects
,samongsothers?s-sans✔✔Fever,ssweating,sagitation,srapidsheartbeat
Asnursescounselssaspatientswhoshassbeensprescribedsasmonoaminesoxidasesinhibitors(MA
OI)stostreatsdepressionstosavoidsfoodsscontainingstyramine.sWhichsofsthesfollowingsfoodsssh
ouldsthespatientsavoid?s(selectsallsthatsapply)s-sans✔✔Yogurt,stofu,spepperoni
Aspatientswithssevereskidneysdiseasesissstartedsonslithiumsbysasnewsresident.sAssthesnurses
onsdutysyoursbestsinitialsresponseswouldsbesto:s-
sans✔✔Contactsthesresidentstosremindshimsthatsthesclientshasskidneysdiseasesandslithiumsis
scontraindicated
,Whichsofsthesfollowingsissgenerallystruesofsmedicationssusedstostreatsanxietysdisorders?s-
sans✔✔Justsasswith sdepression,sthesmostscommonsmedicationssprescribedsaresserotoninsr
euptakesinhibitorss(SSRIs)sandsselectivesnorepinephrinesreuptakesinhibitorss(SNRIs).
Forswhichsonesofsthesfollowingstypessofsdrugssissthesconsumptionsofsgrapefruitsjuicescontrai
ndicated?s-sans✔✔Second-generationsantipsychotics
Psychopharmaceuticalsagentssaresprescribedsforsindividualsswithssubstancesusesdisorders
sforsallsofsthesfollowingsreasonssexcept:s-
sans✔✔Toselevatesthespatient'ssmoodsinsasmannerscomparablestosthesactionsofsthesmisuse
dssubstance
Aspatientshassbeensprescribedsdisulfiram.sThesnurseswouldsmostsappropriatelyscounselsthe
spatientsaboutswhich sofsthesfollowing? s-sans✔✔Astoxicsreactionsifsalcoholsissconsumed
Whensaspatientsissprescribedsrisperidonesforsschizoaffectivesdisorder,sthesnursesmustsalerts
thespatientstosthespotentialsforsneurolepticsmalignantssyndrome.sWhichsofsthesfollowingswou
ldsbesaccuratesinformationstosgivesthespatient?s-
sans✔✔Neurolepticsmalignantssyndromesisspotentiallysfatal.sItsusuallysoccurssduringsthesfir
sts2sweekssaftersstartingsansantipsychoticsdrugsorsincreasingsthesdosesandsisscharacterizeds
byshighsfever,smusclesstiffness,sparanoia,ssweating,sandslargeschangessinsbloodspressure.
Asclientswithsdepressionsisstakingsphenelzine.sThesnursesadvisessthesclientstosavoidsconsu
mingswhichsfoodsswhilestakingsthesmedications-sans✔✔Yogurt
MethylphenidatesissasCNSsstimulantsandsissthesdrugsofschoicesforsindividualsswithsattention-
deficit/hyperactivitysdisorders(ADHD).sThesdesiredseffectssofsmethylphenidatesmaysbesnote
dsas:s-sans✔✔Increasedsattentionsspansandsconcentration
Thesrisksofsexperiencingsserotoninssyndromeswhensselectivesserotoninsreuptakesinhibitorss
(SSRIs)saresgivenswithsmonoaminesoxidasesinhibitorss(MAOIs)ssuchsassphenelzine.sSerot
oninssyndromesissbestscharacterizedsinswhichsofsthesfollowing?s-
sans✔✔Musclesrigiditysandshighsfever
As19-year-
oldsfemalesclientswithsdepressionswhoshassbeenstakingsamitriptylinesforsthreesweekssreturn
sstosthesclinicsforsasfollow-
up.sThesnursesanticipatessthespossibilitysofsobservingswhichsofsthesfollowingssymptoms?s-
sans✔✔Suicidalsthoughts
Asnewlysadmittedsclientshassstartedstakingsbupropion.sThesnursesunderstandsswhichsofsthes
followingssideseffectssthatswouldsindicatesansoverdosesofsthesmedication?s-sans✔✔Seizure
, Asclientstakingslithiumscarbonatesstartedscomplainingsofsnausea,svomiting,sdiarrhea,sdrowsi
ness,smusclesweakness,stremor,sblurredsvisionsandsringingsinsthesears.sTheslithiumsserumsl
evelsiss2smEq/L.sThesnursesinterpretssthissvaluesas:s-sans✔✔Toxicslevel
Whichsofsthesfollowingssymptomssissassignsofsmildslithiumstoxicity:s-
sans✔✔Coursestremorsandslethargy
Asnursesnotessthatsasclientswithsschizophreniasandsreceivingsansantipsychoticsmedicationsis
shavingsuncontrolledsmovementsofstheslipssandstongue.sThesnursesdeterminessthatsthesclien
tsissexperiencing?s-sans✔✔Tardivesdyskinesia
Asclientswithsschizophreniashassbeensstartedsonsmedicationstherapyswithsclozapine.sAsnurs
esassessessthesresultssofswhichslaboratorysstudystosmonitorsforsadverseseffectsrelatedstosthi
ssmedication?s-sans✔✔Whitesbloodscell
Methylphenidatesissprescribedstosans8-year-oldschildsforsthestreatmentsofsattention-
deficit/hyperactivitysdisorders(ADHD).sThesnursesplansstosmonitorswhichsofsthesfollowingsdu
ringsthesmedicationstherapy?s-sans✔✔Heightsandsweights
Canscausesslowsgrowthsandsreducedsappetite
Asclientswhoshassbeenstakingsbuspironesforstwosmonthssreturnsstosthesclinicsforsasfollow-
up.sThesnursesdeterminessthatsthesmedicationsisseffectivesifstheresissansabsentsdisplaysof...s-
sans✔✔Feelingssofspanic,sfear,sandsuneasiness
Yourspatientsisstakingsthesantipsychoticsmedicationssclozapinesandsdivalproexssodiums(De
pakote),sbothsofswhichscanscontributestosweightsgain.sForswhatsshouldsthisspatientsbescarefu
llysmonitored?s-sans✔✔Increasedsbloodsglucose
NursesTrinisknowssthatsthesfollowingsdrugsshavesbeensknownstosbeseffectivesinstreatingsobs
essive-compulsivesdisorders(OCD):s-sans✔✔Fluvoxaminesandsclomipramine
Aspatientsdiagnosedswithsschizophreniashasstakensthiothixenes5smg/daysfors4syearsswithsgo
odssymptomscontrol.sToday,sthespatientsissadmittedswithsparanoiasandsauditoryshallucinatio
ns.sThesnursesshouldsdeterminesifsthespatient'sssymptomssaresrelatedsto:s-
sans✔✔Notstakingsthesdrugsassprescribed
Whensaspatientsisstakingsastraditionalsantipsychoticsmedication,sthesnursesshouldsassesssc
arefullysforsextrapyramidalssideseffectss(EPSEs)sparticularly:s-sans✔✔Akathisia
Nortriptylineswassprescribedsforsas68-year-
oldspatientsdiagnosedswithsdepressionsandsinsomnia.sBenefitssspecificstosusesofsnortriptylin
eswouldsinclude:s-sans✔✔Improvedssleepspattern
PRACTICE QUIZ QUESTIONS AND
ANSWERS
Escitalopramsmayscausesserious,spotentiallysfatalsreactionsswhensusedswiths___________
____.s(selectsallsthatsapply)s-sans✔✔Duloxetine,samitriptilyne,ssertraline,sSt.sJohn'ssWorts
Mixingstwosserotoninsagentsscanscausesserotoninssyndrome.
Thestherapeuticseffectssofsimipraminesdevelopsovers_____________.s-
sans✔✔Severalsweeks
ThesFDA-approvedsindicationssforsfluoxetinesinclude:s(selectsallsthatsapply)s-
sans✔✔Obsessivescompulsivesdisorder,smajorsdepressivesdisorder,sbulimiasnervosa
Takingsfoodswithsbuspironesalterssabsorption.s-sans✔✔False
Maysbestakenswithsfoodstosminimizesgastricsirritation
Venlafaxinesissextensivelysmetabolizedsonsfirstspasssthroughsthes___________.s-
sans✔✔Liver
Signssandssymptomssofslithiumstoxicitysinclude:s(selectsallsthatsapply)s-
sans✔✔Slurredsspeech,sdrowsiness
ValproatesacidshassFDA-approvedsindicationssfor:s(selectsallsthatsapply)s-
sans✔✔Acutesmania,ssimplesandscomplexsabsencesseizures,spreventionsof smigraineshead
aches
Atomoxetinesselectivelys____________sthespresynapticsreuptakesofsnorepinephrinesresult
ingsinsa(n)s________________sattentionsspan.s-sans✔✔Inhibits,simproved
Phenelzinesdoessnotsneedstosbesdiscontinuedsseveralsdayssbeforeselectivessurgerysthatsre
quiressanesthesia.s-sans✔✔False
Bupropionscansbesusedsforssmokingscessation.s-sans✔✔True
Methylphenidatesissnotseffectivesforsnarcolepticspatients.s-sans✔✔False
Clozapinesmayscause:s(selectsallsthatsapply)s-
sans✔✔Syncope,sorthostaticshypotension,scardiacsarrests
,Causessbradycardiaswhichscouldsleadstossyncopesandscardiacsarrest
Administeringsrisperidoneswithslevodopasisscontraindicated.s-sans✔✔Trues
Itsdecreasesstheseffectssofslevodopa
Thes___________sformsofsziprasidonesissfrequentlysusedsforscontrolsofsacutelysagitatedspat
ients.s-sans✔✔Intramusculars(IM)
Anticonvulsantssaresfrequentlysusedsassmoodsstabilizerssforsthestreatmentsofsmaniasandsbi
polarsspectrumsdisorderssbecausesthey:s-sans✔✔Reducessynapticskindling
Aspatientswassstartedsonsfluoxetinesforsdepressions3sdayssago.sShesnowscomplainssthatsits"
doesn'tshelp"sandsrefusesstostakesit.sUnderstandingsthespsychopharmacology,sthesnurse'ss
bestsfirstsactionsissto:s-
sans✔✔Discussswithsthespatientsthatsthesestypessofsmedicationssoftenstakesseveralsweekss
beforesseeingsthesresults.
Whichsofsthesfollowingsissascommonssideseffectsofsbothsfirst-sandssecond-
generationsantipsychoticsdrugs?s(selectsallsthatsapply)s-
sans✔✔Extrapyramidalssideseffectsssuchsasspseudo-
parkinsonismsorsacutesdystonia,sneurolepticsmalignantssyndrome,sexcessivessedation
Asmalespatientswhosisstakingsthessecond-
generationsantipsychoticsreportsstosthesnursesthatsheshassobservedsasclearsfluidsleakingsfro
mshissrightsnipplesforsthespastsmonth.sThesnurse'ssbestsinitialsinterventionsis:s-
sans✔✔Informsthespatientsthatsthisscouldsbesassideseffectsofsthesmedication
Thesphysiciansdiscussessthesappropriatenesssofsprescribingsasserotonin/norepinephrinesre
uptakesinhibitors(SNRI)sforsaspatient.sWhichsofsthesfollowingsmedicationssaresinsthisscategor
y?s-sans✔✔Venlafaxinesandsduloxetine
Aspatientshassbeensprescribedsasselectivesserotoninsreuptakesinhibitors(SSRI)sforsdepressi
on.sThesnursesshouldscounselsthespatientsaboutswhichsofsthesfollowingspossiblessideseffects
,samongsothers?s-sans✔✔Fever,ssweating,sagitation,srapidsheartbeat
Asnursescounselssaspatientswhoshassbeensprescribedsasmonoaminesoxidasesinhibitors(MA
OI)stostreatsdepressionstosavoidsfoodsscontainingstyramine.sWhichsofsthesfollowingsfoodsssh
ouldsthespatientsavoid?s(selectsallsthatsapply)s-sans✔✔Yogurt,stofu,spepperoni
Aspatientswithssevereskidneysdiseasesissstartedsonslithiumsbysasnewsresident.sAssthesnurses
onsdutysyoursbestsinitialsresponseswouldsbesto:s-
sans✔✔Contactsthesresidentstosremindshimsthatsthesclientshasskidneysdiseasesandslithiumsis
scontraindicated
,Whichsofsthesfollowingsissgenerallystruesofsmedicationssusedstostreatsanxietysdisorders?s-
sans✔✔Justsasswith sdepression,sthesmostscommonsmedicationssprescribedsaresserotoninsr
euptakesinhibitorss(SSRIs)sandsselectivesnorepinephrinesreuptakesinhibitorss(SNRIs).
Forswhichsonesofsthesfollowingstypessofsdrugssissthesconsumptionsofsgrapefruitsjuicescontrai
ndicated?s-sans✔✔Second-generationsantipsychotics
Psychopharmaceuticalsagentssaresprescribedsforsindividualsswithssubstancesusesdisorders
sforsallsofsthesfollowingsreasonssexcept:s-
sans✔✔Toselevatesthespatient'ssmoodsinsasmannerscomparablestosthesactionsofsthesmisuse
dssubstance
Aspatientshassbeensprescribedsdisulfiram.sThesnurseswouldsmostsappropriatelyscounselsthe
spatientsaboutswhich sofsthesfollowing? s-sans✔✔Astoxicsreactionsifsalcoholsissconsumed
Whensaspatientsissprescribedsrisperidonesforsschizoaffectivesdisorder,sthesnursesmustsalerts
thespatientstosthespotentialsforsneurolepticsmalignantssyndrome.sWhichsofsthesfollowingswou
ldsbesaccuratesinformationstosgivesthespatient?s-
sans✔✔Neurolepticsmalignantssyndromesisspotentiallysfatal.sItsusuallysoccurssduringsthesfir
sts2sweekssaftersstartingsansantipsychoticsdrugsorsincreasingsthesdosesandsisscharacterizeds
byshighsfever,smusclesstiffness,sparanoia,ssweating,sandslargeschangessinsbloodspressure.
Asclientswithsdepressionsisstakingsphenelzine.sThesnursesadvisessthesclientstosavoidsconsu
mingswhichsfoodsswhilestakingsthesmedications-sans✔✔Yogurt
MethylphenidatesissasCNSsstimulantsandsissthesdrugsofschoicesforsindividualsswithsattention-
deficit/hyperactivitysdisorders(ADHD).sThesdesiredseffectssofsmethylphenidatesmaysbesnote
dsas:s-sans✔✔Increasedsattentionsspansandsconcentration
Thesrisksofsexperiencingsserotoninssyndromeswhensselectivesserotoninsreuptakesinhibitorss
(SSRIs)saresgivenswithsmonoaminesoxidasesinhibitorss(MAOIs)ssuchsassphenelzine.sSerot
oninssyndromesissbestscharacterizedsinswhichsofsthesfollowing?s-
sans✔✔Musclesrigiditysandshighsfever
As19-year-
oldsfemalesclientswithsdepressionswhoshassbeenstakingsamitriptylinesforsthreesweekssreturn
sstosthesclinicsforsasfollow-
up.sThesnursesanticipatessthespossibilitysofsobservingswhichsofsthesfollowingssymptoms?s-
sans✔✔Suicidalsthoughts
Asnewlysadmittedsclientshassstartedstakingsbupropion.sThesnursesunderstandsswhichsofsthes
followingssideseffectssthatswouldsindicatesansoverdosesofsthesmedication?s-sans✔✔Seizure
, Asclientstakingslithiumscarbonatesstartedscomplainingsofsnausea,svomiting,sdiarrhea,sdrowsi
ness,smusclesweakness,stremor,sblurredsvisionsandsringingsinsthesears.sTheslithiumsserumsl
evelsiss2smEq/L.sThesnursesinterpretssthissvaluesas:s-sans✔✔Toxicslevel
Whichsofsthesfollowingssymptomssissassignsofsmildslithiumstoxicity:s-
sans✔✔Coursestremorsandslethargy
Asnursesnotessthatsasclientswithsschizophreniasandsreceivingsansantipsychoticsmedicationsis
shavingsuncontrolledsmovementsofstheslipssandstongue.sThesnursesdeterminessthatsthesclien
tsissexperiencing?s-sans✔✔Tardivesdyskinesia
Asclientswithsschizophreniashassbeensstartedsonsmedicationstherapyswithsclozapine.sAsnurs
esassessessthesresultssofswhichslaboratorysstudystosmonitorsforsadverseseffectsrelatedstosthi
ssmedication?s-sans✔✔Whitesbloodscell
Methylphenidatesissprescribedstosans8-year-oldschildsforsthestreatmentsofsattention-
deficit/hyperactivitysdisorders(ADHD).sThesnursesplansstosmonitorswhichsofsthesfollowingsdu
ringsthesmedicationstherapy?s-sans✔✔Heightsandsweights
Canscausesslowsgrowthsandsreducedsappetite
Asclientswhoshassbeenstakingsbuspironesforstwosmonthssreturnsstosthesclinicsforsasfollow-
up.sThesnursesdeterminessthatsthesmedicationsisseffectivesifstheresissansabsentsdisplaysof...s-
sans✔✔Feelingssofspanic,sfear,sandsuneasiness
Yourspatientsisstakingsthesantipsychoticsmedicationssclozapinesandsdivalproexssodiums(De
pakote),sbothsofswhichscanscontributestosweightsgain.sForswhatsshouldsthisspatientsbescarefu
llysmonitored?s-sans✔✔Increasedsbloodsglucose
NursesTrinisknowssthatsthesfollowingsdrugsshavesbeensknownstosbeseffectivesinstreatingsobs
essive-compulsivesdisorders(OCD):s-sans✔✔Fluvoxaminesandsclomipramine
Aspatientsdiagnosedswithsschizophreniashasstakensthiothixenes5smg/daysfors4syearsswithsgo
odssymptomscontrol.sToday,sthespatientsissadmittedswithsparanoiasandsauditoryshallucinatio
ns.sThesnursesshouldsdeterminesifsthespatient'sssymptomssaresrelatedsto:s-
sans✔✔Notstakingsthesdrugsassprescribed
Whensaspatientsisstakingsastraditionalsantipsychoticsmedication,sthesnursesshouldsassesssc
arefullysforsextrapyramidalssideseffectss(EPSEs)sparticularly:s-sans✔✔Akathisia
Nortriptylineswassprescribedsforsas68-year-
oldspatientsdiagnosedswithsdepressionsandsinsomnia.sBenefitssspecificstosusesofsnortriptylin
eswouldsinclude:s-sans✔✔Improvedssleepspattern
