Pharmacology exam 2- UTA(solved & updated)

Pharmacology
exam 2-
UTA(solved &
updated)
what is the method of action of beta blockers? - answer
blocks beta 1 (cardio selective) and/or beta 2 (non-cardio
selective) receptors to reduce BP/CO/Contractility


what are the prototype beta blocking drugs? why are they
different? - answer Propranolol (Inderal)-non-cardio
selective - works on B1 and B2 receptors
Atenolol (Tenormin)-cardio selective -works only on beta 1
receptors


why are beta blockers used? - answer treatment of angina,
post MI, HTN, migraines, glaucoma, HF


what are the major side effects of beta blockers? - answer
SERIOUS: CHF/MI, severe bradycardia, heart block,
dysrhythmias, bronchospasm (noncardio selective),
hypersensitivity reaction

, COMMON: bradycardia, orthostatic hypotension, fatigue,
drowsiness, cold extremities


beta blocker drug interactions - answer loop diuretics
(reduce preload- lower BP)
Calcium channel blockers (decrease BP, slow HR)
insulin (pt may not recognize signs of hypoglycemia)


how will you know if a beta blocker is working? - answer
reduced HR, BP


what is the prototype alpha 1 agonist? what do they treat?
- answer tamsulosin (Flowmax)-BPH
Phentamine (Regitine)- HTN


what is the prototype alpha 2 agonist? - answer Clonidine


what do both alpha agonist drugs treat? - answer HTN


what classes of drugs treat mainly hypertension? - answer
beta blockers, ACE inhibitors, ARBs, Calcium channel
blockers


what is the prototype ACE inhibitor? - answer Lipitor
(Zestril)


what is the prototype ARB? - answer Losartan (Cozaar)