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Antiinflammatory and Antigout Drugs UTA PHARMACOLOGY test with 100- correct answers

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Antiinflammatory and Antigout Drugs UTA PHARMACOLOGY test with 100- correct answers

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Antiinflammatory and
Antigout Drugs UTA
PHARMACOLOGY test
with 100% correct
answers
Inflammation - answer Localized protective response
stimulated by injury to
tissues, which serves to destroy, dilute, or wall off
(sequester) both the injurious agent and the injured
tissue
◦ Pain, fever, loss of function, redness, and swelling
◦ Endogenous compounds, including proteins of the
complement system, histamine, serotonin, bradykinin,
leukotrienes, and prostaglandins


Nonsteroidal Antiinflammatory Drugs NSAID's following
properties - answer Large and chemically diverse group of
drugs with the
following properties:
◦ Analgesic
◦ Antiinflammatory

,◦ Antipyretic
◦ Aspirin-platelet inhibition


NSAIDS con't used for - answer NSAIDs are also used for
the relief of:
◦ Mild to moderate headaches
◦ Myalgia
◦ Neuralgia
◦ Arthralgia
◦ Alleviation of postoperative pain
◦ The pain associated with arthritic disorders, such as
rheumatoid arthritis (RA), juvenile arthritis, ankylosing
spondylitis, and osteoarthritis (OA)
◦ Treatment of gout and hyperuricemia


NSAIDs cont properties all NSAIDs share - answer
Properties all NSAIDs share:
◦ Antipyretic
◦ Analgesic
◦ Antiinflammatory


NSAIDs CONT Salicvlyates are - answer ◦ Aspirin
◦ Diflunisal (Dolobid)
◦ Salsalate (Salistab)
◦ Choline salicylate (Arthropan)

, NSAIDs Cont Acetic Acid derivatives - answer Acetic acid
derivatives
◦ diclofenac sodium (Voltaren)
◦ indomethacin (Indocin)
◦ sulindac (Clinoril)
◦ tolmetin (Tolectin)
◦ etodolac (Lodine)
◦ ketorolac (Toradol)
◦ meclofenamate (generic only)
◦ mefenamic acid (Ponstel)


NSAIDs CONT Cycloxygenase-2 inhibitor drug called -
answer Cyclooxygenase-2 (COX-2) inhibitors
◦ celecoxib (Celebrex)


NSAIDs CONT Enolic acid derivatives - answer Enolic acid
derivatives
◦ nabumetone (Relafen)
◦ meloxicam (Mobic)
◦ piroxicam (Feldene)


NSAIDs CONT Propionic acid derivatives - answer Propionic
acid derivatives
◦ fenoprofen (Nalfon)
◦ flurbiprofen (Ansaid)
◦ ibuprofen (Motrin, Advil, others)

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