NURS 676 UNIT III CH. 8-10 REVIEW
QUESTIONS AND CORRECT ANSWERS
CHANGES THAT HAPPEN DURING PREGNANCY ✅CHANGES IN THE KIDNEY,
LIVER, GI TRACT
WHAT HAPPENS TO THE KIDNEYS DURING THE THIRD TRIMESTER? ✅RENAL
BLOOD FLOW IS DOUBLED CAUSING LARGE INCREASE IN GLOMERULAR
FILTRATION RATE--> ACCELERATED CLEARANCE OF DRUGS ARE ELIMINATED
BY GLOMERULAR FILTRATION
WHAT HAPPENS TO THE LIVER DURING THE 3RD TRIMESTER? ✅HEPATIC
METABOLISM INCREASES DURING PREGNANCY FOR SOME DRUGS
EX: ANTI-SEIZURE MEDS, PHENYTOIN, AND VALPORIC ACID
WHAT HAPPENS TO THE GI TRACT DURING THE 3RD TRIMESTER? ✅TONE
AND MOTILITY OF THE BOWEL DECREASES IN PREGNANCY CASING
INTESTINAL TRANSMIT TIME TO INCREASE
IT TAKES MORE TIME FOR DRUGS TO BE ABSORBED
PLACENTAL DRUG TRANSFER ✅THE PROVIDER SHOULD ASSUME THAT ANY
DRUG TAKEN DURING PREGNANCY WILL REACH THE FETUS
STAGES OF FETAL DEVELOPMENT ✅STAGE 1: PREIMPLANATION/PRESOMITE
PERIOD (CONCEPTION- WK 2)
STAGE 2: EMBRYONIC PERIOD (WK 3-8)
STAGE 3: FETAL PERIOD (WK 9-TERM)
GROSS MALFORMATION CAN OCCUR IN WHAT STAGE ✅ARE PRODUCED BY
EXPOSURE TO TERATOGENS DURING THE EMBRYONIC PERIOD (1ST
TRIMESTER)
TERATOGEN EXPOSURE DURING THE FETAL PERIOD WILL DISRUPT
✅FUNCTION RATHER THAN GROSS ANATOMY
THREE CRITERIA FOR A DRUG TO BE A TERATOGEN ✅1. MUST CAUSE A
CHARACTERISTIC SET OF MALFORMATIONS
2. MUST ACT ONLY DURING A SPECIFIC WINDOW OF VULNERABILITY
3. INCIDENCE OF MALFORMATIONS SHOULD INCREASE WITH INCREASING
DOSAGE AND DURATION OF EXPOSURE
QUESTIONS AND CORRECT ANSWERS
CHANGES THAT HAPPEN DURING PREGNANCY ✅CHANGES IN THE KIDNEY,
LIVER, GI TRACT
WHAT HAPPENS TO THE KIDNEYS DURING THE THIRD TRIMESTER? ✅RENAL
BLOOD FLOW IS DOUBLED CAUSING LARGE INCREASE IN GLOMERULAR
FILTRATION RATE--> ACCELERATED CLEARANCE OF DRUGS ARE ELIMINATED
BY GLOMERULAR FILTRATION
WHAT HAPPENS TO THE LIVER DURING THE 3RD TRIMESTER? ✅HEPATIC
METABOLISM INCREASES DURING PREGNANCY FOR SOME DRUGS
EX: ANTI-SEIZURE MEDS, PHENYTOIN, AND VALPORIC ACID
WHAT HAPPENS TO THE GI TRACT DURING THE 3RD TRIMESTER? ✅TONE
AND MOTILITY OF THE BOWEL DECREASES IN PREGNANCY CASING
INTESTINAL TRANSMIT TIME TO INCREASE
IT TAKES MORE TIME FOR DRUGS TO BE ABSORBED
PLACENTAL DRUG TRANSFER ✅THE PROVIDER SHOULD ASSUME THAT ANY
DRUG TAKEN DURING PREGNANCY WILL REACH THE FETUS
STAGES OF FETAL DEVELOPMENT ✅STAGE 1: PREIMPLANATION/PRESOMITE
PERIOD (CONCEPTION- WK 2)
STAGE 2: EMBRYONIC PERIOD (WK 3-8)
STAGE 3: FETAL PERIOD (WK 9-TERM)
GROSS MALFORMATION CAN OCCUR IN WHAT STAGE ✅ARE PRODUCED BY
EXPOSURE TO TERATOGENS DURING THE EMBRYONIC PERIOD (1ST
TRIMESTER)
TERATOGEN EXPOSURE DURING THE FETAL PERIOD WILL DISRUPT
✅FUNCTION RATHER THAN GROSS ANATOMY
THREE CRITERIA FOR A DRUG TO BE A TERATOGEN ✅1. MUST CAUSE A
CHARACTERISTIC SET OF MALFORMATIONS
2. MUST ACT ONLY DURING A SPECIFIC WINDOW OF VULNERABILITY
3. INCIDENCE OF MALFORMATIONS SHOULD INCREASE WITH INCREASING
DOSAGE AND DURATION OF EXPOSURE
