MS medications and indications
sc every other day - ✔✔Betaseron, Extavia dosing
IM once weekly - ✔✔Avonex dosing
sc tid weekly - ✔✔Rebif dosing
sq every 14 days - ✔✔Plegridy dosing
Copaxone - ✔✔Glatiramer acetate brand
Novantrone - ✔✔Mitoxantrone brand
IV q3 months - ✔✔mitoxantrone dosing
myelosupp, myocardial toxic, leukemia - ✔✔Mitoxantrone BBW
Tysabri - ✔✔Natalizumab brand
IV q4w in registered facility - ✔✔Natalizumab dosing
liver damage, PML - ✔✔natalizumab adr
nausea, alopecia, menstrual disorders (blu/green urine) - ✔✔mitoxantrone adr
flulike symptoms, liver abnormalities, depression, hypo/hypertension - ✔✔IFN adr
caution in pt with previous immunosuppressive agents
have positive antibody for JC virus
have received this treatment for >2 years - ✔✔Natalizumab BBW
Gilenya - ✔✔Fingolimod brand
, ketoconazole - ✔✔Fingolimod DDI
increase LFT, slow hr, macular swelling, syelosuppression - ✔✔Fingolimod ADR
po once daily - ✔✔fingolimod dosing
aubagio - ✔✔Teriflunomide brand
teratoginicity, hepatotoxicity - ✔✔Teriflunomide BBW
po once daily - ✔✔Teriflunomide dosing
Tecfidera - ✔✔Dimethly Fumarate brand
Po bid - ✔✔Dimethyl fumarate dosing
lemtrada - ✔✔alemtuzumab brand
autoimmune condition, infusion rxn, malignacies - ✔✔alemtuzumab bbw
IV for 5 days, then daily for 3 days 1 year later - ✔✔alemtuzumab dosing
ocrevus - ✔✔ocrelizumab brand
IV day 1, 14 then q6mo after - ✔✔ocrelizumab dosing
hepatitis b - ✔✔ocrelizumab is CI in
mavenclad - ✔✔cladribine brand
2 cycles 1st year, 2 cycles 2nd year, then 2 year break - ✔✔cladribine dosing
malignancy, tetragenicity - ✔✔cladribine bbw
IV corticosteroids methylpred 3-10days
sc every other day - ✔✔Betaseron, Extavia dosing
IM once weekly - ✔✔Avonex dosing
sc tid weekly - ✔✔Rebif dosing
sq every 14 days - ✔✔Plegridy dosing
Copaxone - ✔✔Glatiramer acetate brand
Novantrone - ✔✔Mitoxantrone brand
IV q3 months - ✔✔mitoxantrone dosing
myelosupp, myocardial toxic, leukemia - ✔✔Mitoxantrone BBW
Tysabri - ✔✔Natalizumab brand
IV q4w in registered facility - ✔✔Natalizumab dosing
liver damage, PML - ✔✔natalizumab adr
nausea, alopecia, menstrual disorders (blu/green urine) - ✔✔mitoxantrone adr
flulike symptoms, liver abnormalities, depression, hypo/hypertension - ✔✔IFN adr
caution in pt with previous immunosuppressive agents
have positive antibody for JC virus
have received this treatment for >2 years - ✔✔Natalizumab BBW
Gilenya - ✔✔Fingolimod brand
, ketoconazole - ✔✔Fingolimod DDI
increase LFT, slow hr, macular swelling, syelosuppression - ✔✔Fingolimod ADR
po once daily - ✔✔fingolimod dosing
aubagio - ✔✔Teriflunomide brand
teratoginicity, hepatotoxicity - ✔✔Teriflunomide BBW
po once daily - ✔✔Teriflunomide dosing
Tecfidera - ✔✔Dimethly Fumarate brand
Po bid - ✔✔Dimethyl fumarate dosing
lemtrada - ✔✔alemtuzumab brand
autoimmune condition, infusion rxn, malignacies - ✔✔alemtuzumab bbw
IV for 5 days, then daily for 3 days 1 year later - ✔✔alemtuzumab dosing
ocrevus - ✔✔ocrelizumab brand
IV day 1, 14 then q6mo after - ✔✔ocrelizumab dosing
hepatitis b - ✔✔ocrelizumab is CI in
mavenclad - ✔✔cladribine brand
2 cycles 1st year, 2 cycles 2nd year, then 2 year break - ✔✔cladribine dosing
malignancy, tetragenicity - ✔✔cladribine bbw
IV corticosteroids methylpred 3-10days
