Case 11
Learning goals:
1. How does sequence alignment work? gap penalty
2. How does the blast method work?
3. How to properly interpret all the results
4. Compare nucleotide proteins
, Leg gap penalty uit.
Kijk veel youtube video’s om het te begrijpen.
Query.
Heuristic method, sealing.
https://blast.ncbi.nlm.nih.gov/Blast.cgi
different between blosum62 and blosum45
blosum62: you can compare 62%.
when the number is lower, there is more distance
pam: number of mutations per 100. Higher number means more distanced
homology: common ancestors
paralogue/orthologue.
Learning goals:
1. How does sequence alignment work? gap penalty
2. How does the blast method work?
3. How to properly interpret all the results
4. Compare nucleotide proteins
, Leg gap penalty uit.
Kijk veel youtube video’s om het te begrijpen.
Query.
Heuristic method, sealing.
https://blast.ncbi.nlm.nih.gov/Blast.cgi
different between blosum62 and blosum45
blosum62: you can compare 62%.
when the number is lower, there is more distance
pam: number of mutations per 100. Higher number means more distanced
homology: common ancestors
paralogue/orthologue.
