SBB GENETIC, RH AND RBC MEMBRANE EXAM / 90 + QUESTIONS AND CORRECT ANSWERS 2024/2025 GRADED A+ .

SBB GENETIC, RH AND RBC MEMBRANE EXAM / 90 + QUESTIONS AND CORRECT ANSWERS 2024/2025 GRADED A+ . 2 / 6 1. dCE: ry 2. DCE: RZ 3. HardyWeinberg equation: Used to calculate allele and genotype frequencies ina population when the frequency of one genetic trait is known 4. HLA antigens: Certain characteristics of blood group and antigens make them useful tools for parentage analysis 5. Direct exclusion, indirect excursion: Assuming maternity is correct, paternitycan be excluded in one of two ways 6. Genetic markers present in the child but is absent from the mother and alleged father: Direct exclusion 7. Child lacks a genetic marker that alleged father (given his observed pheno-type) must transmit to his offspring: Indirect exclusion 8. Example of direct exclusion: If the child is blood group Bmother is blood group O Alleged father is group O what kind of exclusion is this, direct or indirect 9. HLA antigens are inherited as haplotypes: HLA antigens are inherited as 10. This is an example of indirect exclusion It's indirect because we presume the father is JK (b+b+): If the child is Jk(a+b-)Mother Jk(a+b+) alleged father is Jk(a-b+) Is this an example of direct or indirect exclusion? 11. Silent gene: Do not overlook the possibility of a when solv-ing genetic problems 12. Paternity index (PI): Chance that the AF is the biologic father compared to thechance that a random man is the father 13. Biologic father =genetically proven fatherAF = alleged father 3 / 6 Random man =untested man ofsame racial background: Asrelated to paternitycalculations define Biologic fatherAF random man 14. RHD and RHCE genes: Rh antigens are formed by two genes 15. Chromosome 1: Which chromosome is RHD AND RHCE on? 16. Chromosome 19: Which chromosome is the LW glycoproteins on? 17. RHAG is on Chromosome 6: Rh associated glycoprotein (RHAG)is on which chromosome 18. 97% identical and 32 to 35 different amino acids: RHD and RHCE genes are % identicalAnd different amino acids 19. RHD: The absence or mutation of the gene makes a person Dnegative 20. True: The C/c and E/e antigens are found on a single proteinTrue or False 21. True: Some partial D's can type as Rh negativeTrue or False 22. Rosenfeld: Of the three RH nomenclatures Fisher Race, Weiner, Rosenfieldwhich is devoid of inheritance theory? 23. The 1980s: What decade was the start of Rh molecular biology and purificationof Rh D polypeptides 24. The 1990s: What decade started the cloning of Rh genes and molecular basesof D+ and D -phenotypes 25. RHD gene: Polypeptide carries the D antigen on the gene 26. True: Rh proteins are neither glycosylated nor phosphorylated which meansthere are no carbohydrates attached to proteins True or False 27. Inerchain: Chemically modified anti-D is used in determining Rh positiverosettes it splits the disulfide bonds 28. Definition of blood groups: Blood groups are defined by individual differencesin proteins and/or carbohydrates that make up part of the red bl