NSG 552- psychopharmacology Quiz #1

The study of the use of psychotropic medications in the treatment of psychiatric disorders: Psychopharmacology The study of what the body does to drugs: Pharmacokinetics Previous Play Next Rewind 10 seconds Move forward 10 seconds Unmute 0:00 / 0:15 Full screen Brainpower Read More The study of what the drugs does to the body: Pharmacodynamics Involves the absorption, distribution, metabolism and excretion of meds: First Pass Metabolism (C.Y.P. 450) Increase serum levels of other drugs that are substrates of that enzyme: Enzyme inhibitors will slow down metabolism causing toxic levels Decreases serum levels of other drugs that are substrates of that enzyme: Enzyme inducers cause fast metabolism and create subtherapeutic drug levels Part of the brain that regulates powerful emotions such as fear, rage, sexual desires: Amygdala The relay station for sensory information: Thalamus Essential for maintaining homeostasis, controls basic needs such as sleep- wake cycles: Hypothalamus This lobe is involved in executive functioning, high order planning, speech and motivation: Frontal Lobe/ Prefrontal cortex Derived from Tryptophan and made in the Ralphe Nuclei: Serotonin Made in the Locus Ceruleus and involved in the noradrenergic pathways: Norepinephrine 90% of serotonin receptors are found in the: GI tract Produced in the V.T.A. (Reward Pathway) and involved in the four major pathways: Dopamine Dopamine inhibits prolactin in this pathway: Tuberoinfundibular Increase dopamine in this pathway is associated with positive symptoms: Mesolimbic Pathway Decrease dopamine in this pathway is associated with negative symptoms: Mesocortical Pathway Decrease dopamine in this pathway produces motor symptoms: Nigrostriatal Pathway Main inhibitory neurotransmitter that induces calmness and relaxation: Gamma- aminobutyric acid (GABA), Off switch Main excitatory neurotransmitter: Glutamate, On Switch Major organ that breaks down drugs in the body: Liver Electrolyte imbalance commonly associated with psychotropic medication use: Hyponatremia The time needed to clear 50% if drugs from the plasma: Half-life The process of becoming desensitized and less responsive to a particular medication dose overtime necessitating an increase: Tolerance