NURS 676 ADVANCED PHANURS 676 ADVANCED PHARMACOLOGYRMACOLOGY

NURS 676 ADVANCED PHARMACOLOGY FINAL EXAM [QUESTIONS AND ANSWERS WELL ELABORATED BELOW FOR A+ STUDENTS] Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy? - -ANS---To inhibit the development of tolerance What drug can exacerbate the symptoms of GERD? - -ANS---Verapamil (Calan). What would be the best option to treat a newly diagnosed patient with a low TSH level with? - -ANS---Propanolol (Inderal) What does a low level of thyroid-stimulating hormone indicate? - -ANS---Hyperthroidism Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - -ANS--- Aldosterone antagonist Heparin exerts its therapeutic action by what? - -ANS---Upregulating the activity of one of the body's natural anticoagulant molecules, antithrombin III What physiologic action happens when the offending drug is administered during an anaphylactic reaction. - -ANS---Mast cells liberate large doses of histamine. What is the first choice of drug therapy for the majority of patients with uncomplicated stage I hypertension? - -ANS---Thiazide diuretics What are two systemic psoriasis medications? - -ANS---Photo-therapy and topical corticosteroids What is the effect of cardiac glycosides? - -ANS---Digitalis glycosides have a negative