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Summary

Samenvatting HC 4 oefenopgaven

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Extra oefenppgaven op basis van HC 4 verdelingsevenwichten. Er wordt hier bijvoorbeeld behandeld: extractielogdextractieopbrengstorganische fase

Institution
Universiteit Utrecht (UU)
Module
FA BA103 Toediening van geneesmiddelen (FABA103)

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FA-BA103
Hoorcollege Verdelingsevenwichten
Formules en rekenvoorbeelden

Deze rekenvoorbeelden komen o.a. uit het hoorcollege en horen bij de toetsstof.
Formules
[𝑆]𝑜𝑟𝑔 𝐶𝑜
𝐾=𝑃= =
[𝑆]𝑎𝑞 𝐶𝑤

𝐶𝑜 [𝐻𝐴] 𝑜 +[𝐴−] 𝑜 [𝐻+]⬚ ∗[𝐴−]⬚
D= = en K =
𝐶𝑤 [𝐻𝐴]𝑤 +[𝐴−] 𝑤 [𝐻𝐴] ⬚
-
D= (fractie HA* P ) + (fractie A * P )
HA A-


𝑛𝑜𝑟𝑔 𝑃 𝑛𝑜𝑟𝑔
= 𝑚𝑒𝑡 %𝐸 = 100
𝑛𝑡𝑜𝑡 𝑃 + (𝑉𝑎𝑞 /𝑉𝑜𝑟𝑔 ) 𝑛𝑡𝑜𝑡


𝑛𝑎𝑞 𝑛𝑜𝑟𝑔 (𝑉𝑎𝑞 /𝑉𝑜𝑟𝑔 ) 𝑛𝑎𝑞
=1− = 𝑚𝑒𝑡 %𝐸 = 100
𝑛𝑡𝑜𝑡
𝑛𝑡𝑜𝑡 𝑛𝑡𝑜𝑡 𝑃 + (𝑉𝑎𝑞 /𝑉𝑜𝑟𝑔 )

n
𝑛𝑎𝑞 n (𝑉𝑎𝑞 /𝑉𝑜𝑟𝑔 )
൬ ൰ =ቆ ቇ
𝑛𝑡𝑜𝑡 𝑃 + (𝑉𝑎𝑞 /𝑉𝑜𝑟𝑔 )

n
P × Vf
Opbrengst zuur in organische fase: Eorg = 100% × ቆ1 − ൬1 − ൰ ቇ
P × Vf + 1 + 10pH−pKa

n
P × Vf
Opbrengst base in organische fase: Eorg = 100% × ቆ1 − ൬1 − ൰ ቇ
P × Vf + 1 + 10pKa−pH
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Institution
Universiteit Utrecht (UU)
Study
Farmacie
Module
FA BA103 Toediening van geneesmiddelen (FABA103)

Document information

Uploaded on
July 16, 2024
Number of pages
4
Written in
2023/2024
Type
SUMMARY

Subjects

  • extractie
  • logd
  • extractieopbrengst
  • organische fase
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