NAPSRx CNPR EXAM (REVISED 18TH
EDITION)
NAPSRx CNPR EXAM (REVISED 18TH EDITION){ACCURATE ANSWERS}
What does a STAT order mean? - Accurate Answer ✅✅a drug needed immediately and given only once.
What information does the overdosage section of the labeling provide? - Accurate Answer ✅✅signs, symptoms and treatment of acute overdoses.
Types of drug-drug interactions: - Accurate Answer ✅✅duplication, opposition (antagonism) and alteration (p.51).
Tolerance vs resistance - Accurate Answer ✅✅tolerance is the diminished response to a drug; resistance is the cells ability to resist the effects of the drug on them.
Abbreviated new drug application (ANDA) - Accurate Answer ✅✅the process by which applicants must scientifically demonstrate to the FDA that their generic product is bioequivalent to or performs in the same way as the innovator drug, no duplicate testing (p. 75). The Hatch-Waxman Act of 1984 - Accurate Answer ✅✅-A.K.A. Drug Price Competition and Patent Restoration Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic cooling off period once an ANDA is challenged for patent infringement (p. 75)
Four basic transport mechanisms - Accurate Answer ✅✅passive diffusion, facilitated diffusion, active transport, and pinocytosis (p. 95).
Potency vs efficacy - Accurate Answer ✅✅potency: amount of drug necessary to produce desired effect
Efficacy: magnitude of maximal response that can be received from a drug
*efficacy is almost always more important that potency* (p. 106)
The four phases of clinical trials - Accurate Answer ✅✅phases I-IV (P . 124-126)
Key Parts Of A Clinical Paper (5) - Accurate Answer ✅✅Abstract, Introduction, methods, results, discussion/conclusions (p. 128-129)
Reliability vs validity - Accurate Answer ✅✅reliability = consistency and validity = accuracy
(p. 138; 143)
Sampling error vs selection bias - Accurate Answer ✅✅sampling error is unbiased and is randomly chosen from the population. Selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
Independent vs dependent variable - Accurate Answer ✅✅An independent variable is the one that influences the variation. A dependent variable is the variable being tested and measured in a scientific experiment (the result of applying the independent variable).
Drug Utilization Review (DUR) programs - Accurate Answer ✅✅-involve retrospective monitoring of physicians' prescribing patterns
EDITION)
NAPSRx CNPR EXAM (REVISED 18TH EDITION){ACCURATE ANSWERS}
What does a STAT order mean? - Accurate Answer ✅✅a drug needed immediately and given only once.
What information does the overdosage section of the labeling provide? - Accurate Answer ✅✅signs, symptoms and treatment of acute overdoses.
Types of drug-drug interactions: - Accurate Answer ✅✅duplication, opposition (antagonism) and alteration (p.51).
Tolerance vs resistance - Accurate Answer ✅✅tolerance is the diminished response to a drug; resistance is the cells ability to resist the effects of the drug on them.
Abbreviated new drug application (ANDA) - Accurate Answer ✅✅the process by which applicants must scientifically demonstrate to the FDA that their generic product is bioequivalent to or performs in the same way as the innovator drug, no duplicate testing (p. 75). The Hatch-Waxman Act of 1984 - Accurate Answer ✅✅-A.K.A. Drug Price Competition and Patent Restoration Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic cooling off period once an ANDA is challenged for patent infringement (p. 75)
Four basic transport mechanisms - Accurate Answer ✅✅passive diffusion, facilitated diffusion, active transport, and pinocytosis (p. 95).
Potency vs efficacy - Accurate Answer ✅✅potency: amount of drug necessary to produce desired effect
Efficacy: magnitude of maximal response that can be received from a drug
*efficacy is almost always more important that potency* (p. 106)
The four phases of clinical trials - Accurate Answer ✅✅phases I-IV (P . 124-126)
Key Parts Of A Clinical Paper (5) - Accurate Answer ✅✅Abstract, Introduction, methods, results, discussion/conclusions (p. 128-129)
Reliability vs validity - Accurate Answer ✅✅reliability = consistency and validity = accuracy
(p. 138; 143)
Sampling error vs selection bias - Accurate Answer ✅✅sampling error is unbiased and is randomly chosen from the population. Selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
Independent vs dependent variable - Accurate Answer ✅✅An independent variable is the one that influences the variation. A dependent variable is the variable being tested and measured in a scientific experiment (the result of applying the independent variable).
Drug Utilization Review (DUR) programs - Accurate Answer ✅✅-involve retrospective monitoring of physicians' prescribing patterns
