Maryville University NURS 615 Pharmacology Exam 4 With Complete Solution (Already graded A+)

Maryville University NURS 615 Pharmacology Exam 4 With Complete Solution (Already graded A+) What are examples of inhaled Short-acting Beta Agonists? (SABAs) - -Albuterol and levabuterol What is the MOA of inhaled beta agonists? - -To relax airway smooth muscle by increasing cyclic cAMP; dilation and opening of airway What is the use of inhaled beta agonists? - -Used in bronchospasm associated with: asthma, bronchitis, and COPD When are SABAs used (albuterol and levabuterol)? - -For relief of ACUTE asthma attacks Is albuterol approved in children under 4? - -Yes. How do beta-2 agonists affect calcium? - -They open large conductions in calcium activated potassium channels = hyperpolarized airway smooth muscle cells 1. decreased intracellular calcium 2. increased potassium concentration 3. decreased myocleynase activity = smooth muscle relaxation and bronchodilation What are examples of long-acting beta agonists (LABAs)? - -salmetrol and formoterol What are LABAs (salmeterol and formoterol) used for? - -Used for PREVENTION or long term treatment of asthma NOT for acute attack