Introduction to Clinical Pharmacology Practice Questions and Answers

Pharma reps need a solid understanding of 3 things 1.) Anatomy 2.) Physiology 3.) Clinical pharmacology Anatomy the study of the basic structures of the body Physiology the study of how those body structures function Clinical Pharmacology study of the effects and movement of drugs in the human body How many prescriptions dispensed each year in the US? more than 3 billion the ____ recorded the earliest surviving prescriptions Babylonians Pen Tsao (Great Herbal) -recorded by the chinese and it was a 40 volume compendium of plant remedies dating to 2700BC Ebers Papyrus Egyptian archived remedies dating back to 1500BC Fredrich Serturner first isolated morphine in 1805 and injected it into himself and 3 friends in a huge dose John Jacob Abel father of American pharmacology University of Michigan in 1890 Basic clinical pharmacology involves three main concepts 1.) Pharmacodynamics 2.) Pharmacokinetics 3.) drug distribution and elimination Pharmacodynamics study of biochemical and physiological effects of drugs and their mechanisms of action ie: study of what drugs do to the body