PEBC Correctly Solved Exam |Question and Answers| 100% Correct

PEBC Correctly Solved Exam |Question and Answers| 100% Correct Thiazide Diuretics AEs 'MICH' -Metolazone -Indapamide -Chlorthalidone (thiazide-like) -HCTZ *Ans* -Impotence -Hypokalemia (inc DIGOXIN toxicity) -Inc Urate (CI in Gout) -Inc BG (CI in DM, lowers antihyperglycemic effect of drugs) -Inc Lipids -Hypotension (effect lowered by NSAIDs) *not effective in renal dysfunction Regulators of Body Temperature *Ans* -urine -skin -sweat glands Teratogenic Drugs cause damage during? *Ans* 2nd- 8th week Components in saliva? *Ans* Lysozyme, IgA, Amylase Factors responsible for transfer of drug across placental barrier *Ans* Conc of drug Molecular size of drug Drug solubility Derived from Tryptophan? *Ans* Niacin, Melatonin, ~5-HTP~5-HT (serotonin) Tx thrombocytopenia *Ans* Oprelvekin (IL-11) Iron *Ans* -most abundant metal in the body -excess: hemochromatosis -antidote OD: deferoxamine Epinephrine derived from? *Ans* Phenylalanine->Tyrosine->Dopa->Dopamine->NE- >EPI Aminoglycoside SEs: 'AMINO' *Ans* Allergy M neuroMuscular blockade Inactivated when physically mixed with B-lactams Nephrotoxicity Ototoxicity, Optic nerve toxicity Lifespan of RBC *Ans* 120 days Lifespan of Platelets *Ans* 7-10 days Most abundant WBC *Ans* Neutrophils 60% RBC sequence of cells *Ans* Hemocytoblast->Megaloblast->Erythroblast (normoblast)