UNMC Patho Exam 1 Questions and Verified Answers | Passed | A+
neuroanatomy of pain and the components of pain : -Nociceptors → Afferent fibers → Spinal cord (substance P) → Brain for interpretation -Substance P = neurotransmitter peptide - has to bind to a receptor -Impulse MUST go to the brain AND be interpreted for the pain to be felt Nociceptors : pain receptors Afferent fibers : -A-delta (for sharp pain) -C-fibers (for dull/achy pain) Spinal cord : -dorsal horn, substantia gelatinosa 2 Substance P : key neurotransmitter Impulse : MUST go to the brain AND be interpreted for the pain to be felt Gate Control theory of pain : -L fibers = large diameter fibers, conduct impulses fast and attempt to EXCITE SG AND T CELLS → decrease of pain perception -S fibers = small diameter fibers, conduct impulses slow and attempt to INHIBIT SG CELLS AND EXCITE T CELLS → increase of pain perception -Substansia Gelatinosa = attempts to INHIBIT T CELL -Central Transmission Cell (T cell) = receives all input, the more excitation of the T cell, the more perception of pain
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