NCLEX Meds (140 Must Know) 2023 WITH COMPLETE SOLUTIONS GRADED A+ (PROVIDES FULL EXPLANATIONS)

Alteplase (t-PA) - ANSWER *class*: thrombolytics *Indication*: MI, acute ischemic stroke, occluded central lines *Action*: converts plasminogen to plasmin which degrades the fibrin found *Nursing Considerations*: - contraindicated in active bleeding -monitor for anaphylaxis - use caution with uncontrolled hypertension Atorvastatin (Lipitor) - ANSWER *class*: lipid-lowering agent *Indication*: management of high cholesterol (hypercholesterolemia), primary prevention of cardiovascular disease *Action*: lowers total cholesterol as well as LDL while slightly increasing HDL. Inhibits HMG-CoA reductase which plays a role in the liver in cholesterol formation *Nursing Considerations* - contraindicated in active liver disease - may cause rhabdomyolysis - monitor serum cholesterol - monitor liver function tests, renal function Acetaminophen (Tylenol) - ANSWER *class*: antipyretic, non-opioid analgesic *Indication*: pain, fever *Action*: inhibit the synthesis of prostaglandins which play a role in transmission of pain signals and fever response *Nursing Considerations*: - do not exceed 4g of acetaminophen per day - overdose will lead to hepatotoxicity - **Acetadote**is the antidote for overdose - may increase risk for bleed with warfarin therapy Acyclovir (Zovirax) - ANSWER *class*: antiviral, purine analogues *Indication*:genital herpes, herpes zoster, chicken pox *Action*: interferes with viral DNA synthesis *Nursing Considerations*: - may cause seizures, renal failure, Stevens-Johnson syndrome, thrombotic thrombocytopenic purpura syndrome, diarrhea, dizziness, nausea - monitor renal function - assess lesions - instruct patient to use proper protection during sexual intercourse Albuterol (Proventil) - ANSWER *class*: bronchodilator ,adrenergic *Indication*:bronchodilator used to prevent airway obstruction in asthma and COPD *Action*: binds to Beta2 adrenergic receptors in the airway leading to relaxation of the smooth muscles in the airways *Nursing Considerations*: - may decrease the effectiveness of Beta Blockers -use caution with: heart disease, diabetes, glaucoma, seizure disorder - overuse of inhalers can lead to bronchospasm - monitor for chest pain and palpitations