Veterinary Pharmacology TOP Exam
Guide Questions and CORRECT Answers
A drug replicated from the original chemical compound - ✔✔✔Bioequivalent
Term for: within safe and effective treatment concentrations - ✔✔✔The therapeutic range
A type of syringe without dead space - ✔✔✔Insulin syringe
Enteric tablet coatings are composed of this. - ✔✔✔Polymer and complex sugar molecules
The time frame considered when consuming products from food producing animals -
✔✔✔Withdrawal time
An acid/base measurement affecting ionization and the ability to absorb and digest drugs -
✔✔✔pH
The barrier in brain capillaries that prevent drugs from entering - ✔✔✔P-glycoprotein
Patients over dosing on drugs excreted by the kidneys should have what administered to
support excretion? - ✔✔✔IV fluids
Another name for a drug's clearance time from the body - ✔✔✔Half life
ADME stands for? - ✔✔✔Absorption, Distribution, Metabolism, Elimination
Non-ionized and easily absorbed by cells but requires more metabolism - ✔✔✔Lipophilic
Ionized and better absorbed into blood stream - ✔✔✔Hydrophilic
, The bioavailability of these two routes of administration is 100% - ✔✔✔IV and IM
This type of safety margin's effectiveness is close to the lethal dose - ✔✔✔Narrow safety
margin
This process makes drugs more water soluble for elimination - ✔✔✔Biotransformation
The portion of the GI tract with the best absorption potential - ✔✔✔Small intestine
Examples of these are the eye, placenta, and blood brain barrier - ✔✔✔Natural barriers
Drugs that stimulate glutamate receptors causing paralysis of the mouth - ✔✔✔Macrolides
Receptor that causes CNS depression - ✔✔✔GABA
Which type of resistance is this: Organism develops enzymes that inactivate the drug
(penicillinase/penicillin) - ✔✔✔Inactivation
Drugs whose MOA is to disrupt protein synthesis on ribosomes - ✔✔✔Macrolides,
tetracyclines, aminoglycosides, lincosamides
Sulfonamides have what method of action as an antimicrobial? - ✔✔✔Affecting enzymes
and metabolites
Group of antimicrobials that can't pass through the blood brain barrier - ✔✔✔Cephalosporins
Gram negative bacteria tighten these to become resistant to antimicrobials - ✔✔✔Pores
Guide Questions and CORRECT Answers
A drug replicated from the original chemical compound - ✔✔✔Bioequivalent
Term for: within safe and effective treatment concentrations - ✔✔✔The therapeutic range
A type of syringe without dead space - ✔✔✔Insulin syringe
Enteric tablet coatings are composed of this. - ✔✔✔Polymer and complex sugar molecules
The time frame considered when consuming products from food producing animals -
✔✔✔Withdrawal time
An acid/base measurement affecting ionization and the ability to absorb and digest drugs -
✔✔✔pH
The barrier in brain capillaries that prevent drugs from entering - ✔✔✔P-glycoprotein
Patients over dosing on drugs excreted by the kidneys should have what administered to
support excretion? - ✔✔✔IV fluids
Another name for a drug's clearance time from the body - ✔✔✔Half life
ADME stands for? - ✔✔✔Absorption, Distribution, Metabolism, Elimination
Non-ionized and easily absorbed by cells but requires more metabolism - ✔✔✔Lipophilic
Ionized and better absorbed into blood stream - ✔✔✔Hydrophilic
, The bioavailability of these two routes of administration is 100% - ✔✔✔IV and IM
This type of safety margin's effectiveness is close to the lethal dose - ✔✔✔Narrow safety
margin
This process makes drugs more water soluble for elimination - ✔✔✔Biotransformation
The portion of the GI tract with the best absorption potential - ✔✔✔Small intestine
Examples of these are the eye, placenta, and blood brain barrier - ✔✔✔Natural barriers
Drugs that stimulate glutamate receptors causing paralysis of the mouth - ✔✔✔Macrolides
Receptor that causes CNS depression - ✔✔✔GABA
Which type of resistance is this: Organism develops enzymes that inactivate the drug
(penicillinase/penicillin) - ✔✔✔Inactivation
Drugs whose MOA is to disrupt protein synthesis on ribosomes - ✔✔✔Macrolides,
tetracyclines, aminoglycosides, lincosamides
Sulfonamides have what method of action as an antimicrobial? - ✔✔✔Affecting enzymes
and metabolites
Group of antimicrobials that can't pass through the blood brain barrier - ✔✔✔Cephalosporins
Gram negative bacteria tighten these to become resistant to antimicrobials - ✔✔✔Pores
