CPIA Complete Solutions

CPIA Complete Solutions What does the Public Service Policy on Humane Care and Use of Laboratory Animal (PHS Policy) implement? the Health Research Extension Act of 1985 The Health Research Extension Act of 1985 directs ______ to establish guidelines for the proper care and treatment of animals used in research the Secretary of Health and Human Services In 1986, the PHS Policy incorporated the ________ by the Interagency Research Animal Committee and adopted by US Government agencies that use vertebrate animals U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training IACUC membership requirements for PHS Assurance 5 members: One veterinarian (training/experience in lab animal medicine) One scientist (experience in research) One nonscientific member One not affiliated member PHS Policy mandates that animal care and use programs must operate in accordance with four specific laws and guidelines 1. The Animal Welfare Act 2. United States Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training 3. The Guide for the Care and Use of Laboratory Animals 4. AVMA Guidelines for the Euthanasia of Animals Code of Federal Regulations, Title 9, Chapter 1, Subchapter A, Parts 1, 2, and 3 Animal Welfare Regulations that are implemented by the USDA/APHIS/AC Clarified humane care, minimization of pain and distress, consideration of alternatives, institutional animal care and use committees, psychological well-being of primates, and exercise for dogs 1985 amendments to the AWA Which term is defined in the Guide as "all measures to control known or unknown infections in laboratory animals." a. Biosecurity b. Stabilization c. Quarantine d. Biosafety a. Biosecurity Which of the following statements about multiple survival surgical procedures on a single animal is TRUE? a. The Guide's definition of "major" surgery is rigid, and does not provide for any interpretation by the veterinarian or the IACUC. b. When USDA-covered species are used, the Animal Welfare Regulations' definition of "major" surgery takes precedence. c. The Animal Welfare Regulations allow for the interpretation of "major" surgery to be evaluated on a case-by-case basis by the IACUC. d. The Guide's requirement that multiple major survival surgeries must be scientifically justified and included in the IACUC-approved protocol only applies to non-rodent mammals. b. When USDA covered species are used, the Animal Welfare Regulations' definition of "major" surgery takes precedence. Animals using which type of thermoregulation depend mostly on environmental temperature to maintain their internal physiology? Poikilothermic Which should be provided in the environment of a semi-aquatic animal? a. porous substrate b. recirculating system c. a terrestrial area d. low humidity level c. a terrestrial area Which statement is TRUE for the use of agricultural animals in biomedical research, when they are maintained in a farm setting? a. These animals are covered by the Guide but not by the Animal Welfare Act. b. These animals are only covered by the Ag Guide. c. These animals are covered by the Animal Welfare Act but not by the Guide. d. These animals are covered by the Guide but will benefit from the principles and practices detailed in the Ag Guide. d. These animals are covered by the Guide but will benefit from the principles and practices detailed in the Ag Guide. What is the minimum space required for a female mouse and her litter? a. 75 in2 b. 51 in2 c. 330 in2 d. 124 in2 b. 51 in2 Which are used to standardize the method for performing specific institutional practices and procedures? a. Policies b. Performance Standards c. Procedures d. Principles c. Procedures The first version of the current Animal Welfare Act Laboratory Animal Welfare Act of 1966 The Act was amended in 1970 and named the Animal Welfare Act 1976 Amendment to the AWA Expanded to cover common carriers (for example, airlines and trucking companies) and to set standards for animal transportation. The amendment introduced health certification prior to transport in certain circumstances. Introduced specific guidelines concerning the humane care and handling of animals in research facilities, such as sanitation, housing and ventilation The Food Security Act of 1985, also called "The Improved Standards for Laboratory Animals Act" 1. Mandated that all personnel using animals in research are appropriately trained. 2. Introduced and defined the role of the Institutional Animal Care and Use Committee or IACUC, and its responsibilities to the Animal and Plant Health Inspection Service (APHIS), a division of the USDA. One of an IACUC's responsibilities is to inspect the institutional animal facilities and all its study areas at least twice per year. 3. Specified that consultation with a veterinarian is necessary in the planning of any procedure that could cause pain or distress to animals. 4. Directed the Secretary of Agriculture to establish rules to provide exercise for dogs and an adequate physical environment for the psychological well-being of non-human primates. 5. Specifies that no animal can be used in more than one major operative procedure from which it recovers unless it is scientifically justified. However, multiple major operative procedures are allowable in certain circumstances, as determined by the USDA, including the provision of v