ACE Inhibitors Pharmacology Nursing Exam Questions and Answers

ACE Inhibitors Pharmacology Nursing Exam Questions and Answers ACE - Correct Answer ️️ -angiotensin-converting enzyme Medications end in PRIL - Correct Answer ️️ -Examples: Captopril, Lisinopril, Ramipril, Quinapril, Benazepril Angiotensin-converting enzyme inhibitor (ACE inhibitors) drugs include: - Correct Answer ️️ -Benazepril (Lotensin) Captopril (Capoten) Enalapril/Enalaprilat (Vasotec oral and injectable) Fosinopril (Monopril) Lisinopril (Zestril and Prinivil) Moexipril (Univasc) Perindopril (Aceon) Quinapril (Accupril) Ramipril (Altace) and Trandolapril (Mavik) How these drugs work? - Correct Answer ️️ -They inhibit the RAAS (renin-angiotensin aldosterone system). Goal of the RAAS? - Correct Answer ️️ -To manage our blood pressure by activating a substance that naturally occurs in our body called Angiotensin II. How it does this? - Correct Answer ️️ -Low blood pressure occurs Kidneys release RENIN into circulation causes ANGIOTENSINOGEN (a protein created and released by the liver) to produce ANGIOTENSIN I then a substance called ANGIOTENSIN- CONVERTING ENZYME (ACE) converts Angiotensin I to ANGIOTENSIN II prevent the conversion of Angiotensin I to Angiotensin II - Correct Answer ️️ -ACE Inhibitors - converts Angiotensin I to Angiotensin II and it inactivates bradykinin by breaking it down (note: inhibiting ACE will increase the amount of bradykinin) - Correct Answer ️️ -ACE is an inflammatory substance that dilates vessels but increased amounts of it are thought to lead to the dry, persistent cough experienced with ACEI