DNA Replication. Exam Mastery Made Easy: Comprehensive Study Guides
A summary of DNA replication 1. Helicases unwind the parental double helix 2. Single-strand binding proteins stabilize the unwound parental DNA 3. The leading strand is synthesized continuously in the 5' --> 3' direction by DNA polymerase. 4. The lagging strand is synthesized discontinuously. Primase synthesizes a short RNA primer, which is extended by DNA polymerase to form an Okazaki fragment. 5. After the RNA primer is replaced by DNA (by another DNA polymerase), DNA ligase joins the Okazaki fragment to the growing strand.
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dna replication exam mastery made easy comprehen
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key characteristics of replication semi conserva