ENDOMEMBRANES EXAM QUESTIONS WITH CORRECT ANSWERS 100% VERIFIED

ENDOMEMBRANES EXAM QUESTIONS WITH CORRECT ANSWERS 100% VERIFIED What are the three major subdivisions of the Endomembrane system? - Correct Answers -Secretory pathway -Lysosomal pathway -Endocytic pathway How do proteins travel through the endomembrane system? - Correct Answers -Proteins only enter through the start of each pathway, (never from the middle) and never leave pathway until they have reached their destination What are 3 types of protein that enter the endomembrane system upon translation? - Correct Answers 1. Proteins destined for secretion 2. Plasma membrane proteins 3. Proteins that are destined to be endomembrane resident proteins What type of proteins does the rough endoplasmic reticulum synthesize? - Correct Answers Proteins destined for secretion, lysosomes, or membranes True or false: the cytosolic surface of the ER have ribosomes - Correct Answers True: these ribosomes are responsible for synthesizing proteins for import into the ER What does the smooth endoplasmic reticulum synthesize? - Correct Answers Lipids and steroids Where do newly synthesized proteins exit the ER? - Correct Answers The transitional ER (where two types of ER meet) How do proteins stay in the ER? - Correct Answers Proteins that stay in the ER have a ER retention signal (KDEL or HDEL sequence based on amino acids) at carboxyl ends -Even if they get out of the ER into the cis cisternae of the Golgi their ER targeting signal gets them sorted into vesicles and brings them back into the ER What is retrograde movement? - Correct Answers Backward movement (from trans to cis) of vesicles