Test Bank For Lippincott Illustrated Reviews: Pharmacology 8th Edition by Karen Whalen graded A+

Test Bank For Lippincott Illustrated Reviews: Pharmacology 8th Edition by Karen Whalen graded A+ Correct answer = D. Tobramycin (an aminoglycoside) is considered a pregnancy risk category D drug which means there is chance for potential harm to the fetus. Nitrofurantoin, amoxicillin (a penicillin), and cephalexin (a cephalosporin) are considered category B. - A 24-year-old pregnant female presents to the urgent care clinic with fever, frequency, and urgency. She is diagnosed with a urinary tract infection (UTI). Based on potential harm to the fetus, which of the following medications should be avoided in treating her UTI? A. Nitrofurantoin. B. Amoxicillin. C. Cephalexin. D. Tobramycin. Correct answer = A. S. pneumoniae resistance to β-lactam antibiotics involves alteration in one or more of the major penicillin-binding proteins. - Which of the following is the primary method of β-lactam resistance with Streptococcus pneumoniae? A. Modification of target site. B. Decreased drug levels due to changes in permeability. C. Decreased drug levels due to an efflux pump. D. Enzymatic inactivation. Correct answer = C. Isoniazid is only active against Mycobacterium tuberculosis, while ceftriaxone, ciprofloxacin, and imipenem are considered broad spectrum due to their activity against multiple types of bacteria and risk for developing a superinfection. - Which of the following agents is considered a narrowspectrum antibiotic? A. Ceftriaxone. B. Ciprofloxacin. C. Isoniazid. D. Imipenem. Correct answer = D. Clindamycin, linezolid, and vancomycin exhibit time-dependent killing, while daptomycin works best