Big summary including all lectures and study designs

Samenvatting
Lecture I - introducton

Infectinn =Thenpreeencenifnandividin nmiicri) nir anieinn
Illnee =nTheniiientnatnwhichnthenmiicri) nir anieincaueeenmIeeue ndaia enn
Pathi en =nAnnir anieinmirneubetance nthatncannpitentalllncaueendieeaee




Wirienmheliinthe ncannbeneeennwithnthennakednele.nPritizianandnbacterianundernthenli htn
iicriecipenandnvirueuenindernelectrinniicriecipe.

Infectinnvenillneee,ntuberculieiel

Mlcibacteriuintuberculieiennien90%naeliptiiatcnmninillneee .n utncannbenreactvatednafernleare.nInn
aniiiunendefcientnpereinme. .nAIDS nitncannreactvatentuberculieientincaueendieeaee/illneeec
PiirnnutritinncannleadntinNutritinalllnAcquirednIiiunenDefcienclnSlndriienmNAIDS

eerincinvereiinlnthentienperiidndurin nwhichnanepecifcnantbidlndevelipenandnbeciieendetectablen
innthenbliid.
Pathi ennenternbidlnandnantbidlnreepineenwillnfilliw.nThenbidlnwillnaddreeenthenpathi en,nbutnthat
takeeneiientieenbefirennuibernifnantbidieenienhi hneniu hntinbenieaeured.nThatnperiidnienalein
callednthenwindiwnperiid.n
Yiunarenalreadlninfected,nbutnbidlndidn’tnpriducednantbidieeneniu hnlet.nSiniiiunenreepinee =n
antbidieeniennitnieaeurablenlet.

,Anchildnwithnundernutritinl

Thliuenm =niipirtantninniiiunendefeneeneletei

 reducednthliicnepitheliui
 expandednextracellularniatrix
 thliicltendepletin
 reducednthliicnhiriine


Spleennm =nijzernipela ,nverwijderin nvannafvaletifennuitnhetnblied

 reducedncellularitl
 dieir anizednwhitenpulp
 eplenicltendepletinnmincreaeednapiptieie
 alteredninfaiiatirlnenvirinient


ineniirriwnm =viriatenvannbliedcellen

 reducedncellularitl
 expandednextracellularniatrix
 alterednetriia
 erlthriidnhlpiplaeia/dleplaeia
 reducednheiatipiietcnpri enitirncelle
 iipairednileliidncellniaturatinnandniibilizatin


Lliphnnideenm =nverwijderin nvannafvaletifennuitnhetnblied,nafweernte enninfectee
 Reducedncellularitl
 Alterednleukicltentrafckin
 Alterednant enntrafckin nthriu hncinduit
 Iipairednbarriernfunctin
 Fewernantbidlnfiriin ncelle


Galtnm = utnaeeiciatednllifiidenteeue =npritectna ainetninvaeiin
 Siallnpelernpatchednandn eriinalncenter
 Fewernintraepithelialnlliphicltee,nn ncellenandnTcelle
 fevernantbidlnfiriin ncellenandnleeeneecretirlni A


Malarianandnhiikwirincanncaueenaneiia

Malarialnplaeiidiui

hiikwirilnduidenalen
Malenwirin8)10ii,nfeialenwirin10)13ii.

,Lar enbucalncavitlnwithncutn nteeth
Lifenepann1nlear,neiietieenlin er.

Lifenclclenduidenale

Ancllietiianduidenale/Necatirnaiericanuen
 Withinn1)2ndalenlarvaendevelipnnmundernwari,nhuiidncinditine n
 Larvaen riwnin/innfeaceenirninneiilnn
 Afern5)10ndalendevelipientnifnninfectiuenlarvaenmcannii ratenandneurvivenfirnweeke n
 Mi ratinnvianveine,nheart,nlun entininteetnenmciu hin nup,naecarienaleinhaventhat
 24nhiurenaferninfectinninninteetnenlarvaenatachnandndevelipnintinadultnwirien
 IfniralllninfectednblnA.nduidenalenninlun npaeea e




Sliptiienhiikwiril
 AneiialnnCaueednblnatachientnandneecretinnifnant)cia ulanten
 Licalnekinnianifeetatinln Griundnitch”ndurin npenetratinnifnthenlarvaenªAirwaleln
 Durin nlun nii ratinlnciu hin ,neputui,nfever..

Hiikwirinandnnutritinln
Irinndefcienclnaneiian+Priteinnialnutritinn+nNutritinalnandn riwthnfailure

Lecture nutriton

Nutritinalnepidiiiili l =nThenetudlnifnthenrelatinehipnbetweennnutritinnandnhealth.

 Tinexaiinenthenrilenifnnutritinninnthenetili lnifndieeaeen
 Tiniinitirnnutritinalnetatuenifnpipulatinen
 Tindevelipnnutritinalninterventinentinpreventndieeaee

Expieure =nfiidnirnnutriente.
Chan enthenfiriulatinnifnthenetudieenbeliwntinrepreeentnetudieenifnfiideln
1.n etancaritenenandnHIVnpri reeeiinnnnIntakenifnvitaiinnAnrichnfiidenandnHIVnpri reeeiin

, 2.nChildnundernnutritinnandnrieknifninfectinnnEner lncineuiednfiidnandnrieknifninfectin
3.nZincnintakenandntuberculieienrieknIntakenifnzincnrichnfiidenme. .neeafiid nandntuberculieienriek

etancaritenenienfiundninnve etableenandnfruitenandninnthenbidlncinvertedntinvitaiinnA.

Dietary intake methods

Dietarlnrecallm =naekin nback l
Pri

 Dietenifnindividualeniverntientendntinbencirrelatedn
 Nitntiencineuiin n
 Miniialneubjectnburdennmninbiiiarkere
Cine

 Requireenekilledninterviewern
 Relieeninnieiirl
 Difcultntineetiatenquantteen
 Variatinninndietniverntienmdalnifnweek,neeaeinalitl n
 Relevantntienperiid
 Liiitedntienfraie


Detailedndietnrecird =nDetailedniealnblniealnrecirdin nifnfiidniteienandnquanttee,npreferablln
wei htednandnrecirdednatnthentienifnthenieal

Pri

 Mirenaccuratenmwei hed n
 Relieenleeeninnieiirln
 Dieennitnrequireneubjectntiniakeneetiatee
Cine

 Hi hneubjectnburdennnmfirneverlniealnliunhaventinwei htnit
 Dietnchan eeninnreepineentinthenpriceeennmiipirtantnine
 Subjectenlikellntiniieeninfiriatin


24Hnrecall =nDetailednlietnifnallnthenfiidencineuiedninnthenpaetn24nhiure.nThennliuncannQuantflnit,n
haventhen randnandnkniwnthenPreparatinn =naekin nbacknivernthenpreviiuendal.

Priln

 Relieenleeeninnieiirln
 Refectenintakenpreviiuendaln– nninalterin neatn nbehaviir
Cinl

 Hi hneubjectnburdennnmliunhaventinfllninnanlitnifn1nwhilendal
 Skilledninterviewern