UNE Medical Bio chem Exam with Guaranteed Accurate Answers
short chain fatty acids and medium chain fatty acids enter mitochondria by: - correct answer Diffusion Under fasting conditions (ratio of insulin to glucagon 1), elevated glucagon will activate which of the following enzymes? - correct answer Hormone sensitive lipase the process of ketogenesis refers to the conversion of acetyl-CoA to which of the following compounds? - correct answer B-hydroxybutyrate A well, 2-year-old female presents to the clinic with symptoms of a viral illness. She had vomiting and diarrhea, weak, hypoglycemic, elevated liver enzymes, NO KETONES in urine. Laboratory analysis shows elevated medium chain fatty acylcarnitines in blood....which abnormality is the likely diagnosis for the child? - correct answer Defect of medium chain coenzyme A dehydrogenase Ketonuria, hyperglycemia and severe acidosis are diagnostic indicators of the presentation of type 1 diabetic ketoacidosis. Which of the following compounds are ketone bodies that would be elevated in serum and urine from a patient in this condition? - correct answer B-hydroxybutyrate and aceotoacetate Which of the following shuttle systems is necessary for the oxidation of long chain fatty acids? - correct answer carnitine B-oxidation of long chain fatty acids is inhibited by: - correct answer Malonyl-CoA An 11-year-old female...thirsty, frequent urination...thin, in the 30th percentile for height and weight....glucose in urine. Evaluation of bloodwork would reveal decreased levels of which of the following compounds or hormones? - correct answer Insulin Malate can be converted to pyruvate in the cytosol. Which of the following compounds is directly generated in this conversion and is essential for fatty acid synthesis? - correct answer NADPH Insulin stimulates lipogenesis through several mechanisms. Which of the following is not an insulin-stimulated process that enhances lipogenesis? - correct answer Decreased activity of the pyruvate dehydrogenase complex Under conditions when glucose oxidation is elevated, the acetyl CoA produced will allosterically activate which of the following enzymes leading to an increase in production of oxaloacetate? - correct answer pyruvate carboxylase An individual consumes a large meal consisting of a cheeseburger and fries. Which of the following intermediates is shuttled out of the TCA cycle to be used as a substrate for fatty acid synthesis? - correct answer citrate Fatty acid synthesis is a multimeric enzyme complex. Which of the following subunits contains pantothenic acid as a cofactor? - correct answer Acyl carrier protein (ACP) Under fasting conditions, acetyl CoA carboxylase will be inhibited by an increase in which of the following compounds? - correct answer Fatty acyl-CoA T
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