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Mindmap Summary of ALL VIRUSES in ONE 'PAGE'

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This Mindmap is ALL YOU NEED for studying all of the medically important viruses. Although it may seem overwhelming at first, it has all the information you need within one (IPad A3) page so you can see and understand the full picture, then zoom in for details. It not only has them all classified according to their structures in a very easy to remember system, but it also summarizes all of the valuable in formation for EACH virus (Structure, Pathogenesis, Virulence Factors, Diseases/ Infections Caused, Treatment, Prevention/ Prophylaxis, etc). Sources - The information from here is taken mostly from 2 books (Greenwood's Medical Microbiology and Crush Step 1), as well as sketchy and Omosis. Therefore, the information presented is verified from multiple sources. Note 1 - Please understand that you will have to zoom in and out a lot while using this document for studying. Note 2 - Please read the box of the "KEY" (located under the title of "Viruses") first, as it is important to understand what every color and abbreviation means, so that you are well oriented. Best of luck with your studies! (Expect similar documents for ALL bacteria, Parasites, and Fungi soon!)

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(Pico-eva-rivs s
PICORNAVIRUS RFOVIRUG
: Enteric Orphan Virus
Respiratory


-



ENTEROVIRUS
R : Human Get
ASTROVTRU S. Astro-star-shaped ROTAVERWS
HEPEVIRUS
POLJOVERU5
(saliva respiratory droplets)
·
: Fecal-oral
↳ :
·
·
High risk
fecal-oral
of more
(contamination
severe infection : 3ut trimester pregnancy patients with removed tonsils
, [GgA) R OTAVIRUS · J P.: I
.
days
,




·
·
Acid-stable-Virus
Replicates f 2 weeks) in
can

tonsils
travel
+
through
Peyer patches
Gf
of GST,
/Acidity of

Spread
Stomach)
via
blood/lymph to motor neurons of anterior howe causing :
ASTROVIRUS ·Entersvia Gotinfecting achreplicatingin tip ofvillus
·
Gastroenteritis Vomiting fever
damaging Villi upon release -sdabsorptio one


HUMAN ASTROVIRUS (1-8) ·Fecatoral (fomites Air-Jovea
, ,

Fatal watery DSARRHEA /#1 cause in children)-due
(recovery is d absorption /fluid accumulation) +
Polo-AsymmetricGesecking ParalysisUPARALVPOLOMYELGS) with
·
loss to 6 , ·
to NSP4 toxin
tosensory
mots
up

ORTHOHEPEVIRUS
·
ELSSA- Direct examination of antigens in 5500L
·
Enters via 6) and infects and replicates at seujenal cells
of antibodiessee
·
Aseptic meningitis -
fever neck pain/stiffness , skin rash, vomiting
,
. ·
Gastroenteritis-In children ,
↳ Diarrhea Vomiting Pausea
elderly immunocompromised patients
, ·
PCR Indirectexamination
Ti therapy
throatofstrollectalswebforPlastic meningitis-virus may
Isolated from P Oral Live attenuated




PARV
Kontamination) & Reoviruses Vaccine
· · :



protesat
HEPATTIS E VIRUS (HEV)
,
fecal-oral
,

GK , & T :
PCR from stool
sample.
·
be absent but cleaning agents (chlorine heat)
·

Lumbar Puncture
=
bleach , high




i
·
outbreaks sensitive to
↳ food/Water-bourne ,
·
T: Supportive :
Proper sanitation and hygeine

.. Saltvaccine tractivated VaccineTiniectionbones Get immesystem
only produce EgG antibi !

COLIVERUS
e.
·
9
·
Travels through GST (Acid Stable) to invade and replicate hepatocytes
EgA antibodies. HEPAT5 T55 -Similar to
en
produces EgG ·
hepatitis A but jaundice is more
pronounced
(high mortality rate)
ERYTH
complication Vaccine-associated paralys ↳ severe/suften onset hepatic failure pregnant
C DLORADO TICK FEVER VIRUS (REOVIRUS)
↳ In ware cases , may cause :
in women




CALCIVIRUS
↳ NEVER turns Chronic (like HAV)

ENTEROVERUS GECHOVERUSLay & COXSACKSEVERS
-EgMaeti-HAV-ACVinfection
Limited to Westere United States
·



Indirect examination of Antibodies by ELESA e
·
T: Wood tick (Dermacentor) + Blood transfusion
↳ COXSACKE A+ B PARVOVIRU
·




:HumanGetFeculoralKontamination F ey
:


acid stable Infection self limiting No specific treatment · . EC3day
myalgia petechial/maculopapular e
·
· are
. , ,
s ·
Grades nasad ca
affected Immune complex

NOROVIRUS
of ASEPTIC MENTNGGSS Children
ASPECTES
·
· -
Main cause most




Y
Sumel ele ·Erythemainfectio
⑮Pestumor areofEncephalitiseAseftwenigitizinChitter ye(special y
in



NOROVIRUS (NORWALK VIRUS) .T:Fecal-Ora (fomites ,
Air-Jovea ·
Hydrops fetalis -




at the back of mouth
·
Transient aplastic
AfHerpaugina-febrileillness
↳ Coxsackie with small red resies e ·
Enters via 6) and infects and replicates at jeujenal cells
PCR, Indirec
·


same as above rashes of palms and soles. Acute Gastroenteritis (# cause if non-bacterial) In all T:
- · -


age groups
↳ Coxsackie B /hepatitis/pancreatitis ↳ Watery explosive Diarrhea
Myocarditis/ pericarditis
- Pleuro Lynia/Bornholm's disease -
fever with extreme unilateral sharp pain in lower chest ·
Outbreaks in closed
, Nausea
communities Vuitingre centers, schools, cruise shis is
↳ 'numbered' Enteroviruses
·
ELSSA-Direct examination of antigens in 5500L
variety of
C3f show theaboveby wtowsDepending ou speciesa
a



tipeof antibodieson and
a Pcr Indirect examina
proteinso
· ·

Lumbar Puncture for Dexamining a septic meningitis
siz
·
T. Supportive hygeine
·
.
Pi
· Coxsackie A and B can also be isolated from throat of S
Supportive.
·. care .·P Good hygien e/sanitation




HEPATOVIRUS ↓s NAKED


-
fecal-oral Kontamination)
WHAV)
· .


HEPATT ES A VIRUS ↳ food/Water-bourne outbreaks




NAKED
· P.: . 3-6 Was 828 days)
Travels invaded e replicate hepatocytes
/AcidStable)to
·
through GS
hitren
Asymptomatic
+
subclinica
usually
·



· HEPATTSS 16 month) fever , fatigue, -
a jaundice Vin abults) , hepatomegaly , pain in right upper quadrate
↳ NEVER turns C hronic (Like HEV)
symposite




D
Within &- Months
↳ directexaminationof AntibodiesgrahetiHAVGVeufective
of Onset

&
·



recommended for travellers to endemic countieshe

tractivatedVaccineand
Bakarino
· P:
Water Purification (via chlorination bleaching , ,
UV radiation, etc)


RHINOVIRUS [
Nose : Now
of ENTEROVERUS
considered
SPECSES]
one



-
~33% due to airo

Respiratory Oveto
UR itslow temperature of




VIRUSES
R Human

RHSNOVERUS :.
·


labile : No GST]




RNA DNA -
-3 Lays
Binds (to SCAM-0) and replicates respiratory mucosa/epithelial cells of nasopharynx Llow Temp -330) :
· in
↑

Common cold' symptoms (#) cause) Rhinorrhea nasal congestion , cough sore/scratchy throat -
·
-


, ,


(sputum)
-
Nose/throat for PCR
.
· swab
-
·
T Supportive
: care ·
P : Infected should cover cough
55
- -




COLOR-CODED KEY : ↓ -
Positive sense
ENV
FAMILY
Negative


CORONAVIRUS
- -
sense




23
35 -

Single Stranded

ds-


& HELICAL
double stranded

GENUS L -
Linear genome




BACOreRate tNAVERWE. Respirator
· R .: Birds Buts ,
.
Small mannals

droplets direct/indirect contant

PECEE
circular genome
5 - -

/

2 34 days




o
Reservoir (2) Transmission (1) , Incubation Period Li e
-




: # -Segmented
5 (# of segments)


-NVELOPED
↑
.


· a l Cells of Wrest ·
PathogenesisVirulence factors
, genome
&




&
PCR Indirect Infections/diseases Replicates NUCLEUS
-

in
·
- antibodies - ·



·
Chest X-ray
-
Shows focal or diffuse inters titial patchy infiltrates ·
Diagnosis >
- -


Replicates in CYTOPLASM

covering cough Treatment (5) , Prevention/Prophylaxis (P)

C ve NAV. RNAvaccine
·




supporti .
C
⑬



Common Coll-causing O#2 cas e
↳ Nasal
Congestion ,
Thinorrhea , sore throat, cough ,
a febrile

Respiratory Syndrome (SAR3)
exidemic t from
Acute
· Severe
-
2003 e




ARS-CoV
Fever , , Headache ,
Malaise myalgias & non-productive (dry) as




teRespiratoryDistressSyndromeAs e
3A failure
-


premonia , hypoxia Respiratory ,



· ↓
I
.


Same as above -




-
Sardi Arabia from camels
MERS-CoV Middleast :
Respiratory Syndrome (MER5) -
2012 epidemic in

same as above




-
HELSCAL
RETROVIRUS POXVIR
LENTIVERUS
HUMAN IMMUNODEFSCIENCY
·
T : Parenteral -J V

Envelope ↳ NOT Spread by
. .




mosquito bloodtransfusion,setually (
Grug use
VIRUS 1 + 2

rishinWomentreceptiveGul ,Verticaltransmissionelira wine Respiratory droplets
(HEV) · . : Humans
R (immune cells fluids)




Ro ORTHOPOX
VARSOLA VIRUS /SM
COW POX : Contact with
·
Enters
Sprevia respiratorytract toinvad




j
,
·
surface glycoproteins-coded by ENV gene

receptors(Cos,CXC4) Small
pox-flu-like illness for 2-4 d
·

of host immune cells (macrophages dendritic cells, helper Fcells CD4" recee
· glyroproteinifVy4-bindto chemokine
to
skin and mucosal
,
↳ Lesions/blisters on




ICOSAHEDRAL
, Corecepter (CR5 required for cell entry
Surrounding Center (Capsid)-Coded by GAG gene
·
Protein 24 (p24) Capsid protein forming capsid
-
:
· PCRp Clinical examination .
. :
Hist
P Live-attenuated
At the center of Viron-coded by POL gene :
VACCINGA The virus use
&NAPolymeraserzyweCreverse
transcriptase) Viral SsRNA <Viru SAN

RNALependent
-
·


· referred Provious
Integrase
to as


MOLLUSCIP
enome-now

mediates naturation assembly of viral particles + inhibition of host
protein Synthesis




RHABDOVIRUS
·




L
3-STAGE DISEASE :




·ute Flutite illness worth MOLLUSCUM
FluiMeSue tourGericuLyuhaheropathy elurged tousee CONTA
J

2 - :




Acquired Immuno-Deficiency Syndrome (ASDS)
·
body throug
Enters
CD 4 count <200 or Aids-defining
symptoms (opportunistic infections)
3 i

Lesions (small copper-colored home-sha


DELTAVIRUS LYSSAVERUS
·
,
& Lymphatenopathy 4 Splenomegaly BEncephalitis 4 Meningitis 4 + any other secondary bacterial fungal viral infections
,

, , ·
Clinical examination
· AfDS dementia Complex + Myelopathy caused by HJV as it crosses blood-brain barrier via infected monocytes/macrophages
-
·
Confirmation via HE staining of Lesion
·
2-Step Liagnosis /Indirect examination of antibodies) :


↳ ELSSA screening for EgM and EgG antibodies (P24 antigen) but
may give false positive results.
: If
positive , then : animal foxe e
↳ Western
Blotting more -

specific test looking for antibodies
,
via
applying serum to paper with common antigens RABTES VIRUS :: Bite ofinfected (Bat Doy, cat, ,




DELTAVIRUS
screening blood donors safe
·: antivirotics at motor end plate and
replicate inside
t sex ·
Enters via world , invade motor neurons
Limiting Viral growth combination of 3 drugs needed for Highly Active Anti-Retroviral Therapy SHAART)
A Binkstothethnicotinicacetylcholine receptorsUsing e surfaceglycoproteins
:
is
a
,

↳ NRT5s Involeoside reverse
transcriptaseinhibitors) : Zidovudine /
zalcitabine ·
serve
↳ NNRTEs (non-nucleoside reverse
transcriptase inhibitors)
↳ Protease inhibitors :I ndinavir saquinavir , HEPATIT55D VIRUS 9ABSE3-rogressesasa fever migrates virus

headache fatigue tingling t numbness
s...



Maarido-inhibits Geit ·
T-
: Parenteral -J V
. .
drug use blood
,
transfusion , Sexually ,
Vertical transmission ·
Painful pharyngeal or
,


Inspiratory
spas ,



spasms
-
,

caused by Water
as Virus

(hydrophobia) or Greathing (aerophobial
Raltegravir-inhibits integrase Re quires CO-INFECTION (Previous or current) with hepatitis B virus to REPLICATE ↳ Dysphagia Foaming of mouth due to spasms + ↑ salivary production dif reaches salivary glands)
·
-




↳ HDV utilizes the HBV Lipoprotein envelope for assembly and transmission ·
At CNS : ENCEPHALST55 , Seizures flaccid Paralysis, Hallucinations Coma Death
, , ,

OURING hepatitisa infection
iftransmissionisLove
↳ SUPERINFECTION a
Microscopy of Grain biopsy revealing NEGRS BODSES evsinophilic cytoplasmic inclusions



PARAMYO
· -




Acceleratespatitis = Fulminant Hepaticore (ASAP) Vaccination
. =RabiesImmuneGlobulinChed-Passiveimmunizationnation
·

·
Acute dangerous Onset) e and


Indirectexamination(Actibodies)-Anti-HIV HDV can't replicate without i re Vaccinationofimals
· ·
Gomestic animals
· as from should be WASHED + STERLIZED As
E

Connected book
 image
Publisher: 2012 ISBN: 9780702040894 Edition: Unknown

Document information

Summarized whole book?
No
Which chapters are summarized?
Viruses
Uploaded on
March 29, 2024
Number of pages
1
Written in
2023/2024
Type
Summary
$15.49

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