CMN 577 Unit 1 Exam Questions with Verified Answers| 100% Correct| 100% Score

CMN 577 Unit 1 Exam Questions with Verified Answers| 100% Correct| 100% Score Acute Intermittent Porphyria - Overview - Acute Intermittent Porphyria (AIP) typically presents in adulthood and in females instead of males. Onset after menopause is rare but possible. Earlier onset in late teens or early 20s is more common. The use of drugs along with intermittent infections are precipitating factors; keep in mind that there are many triggers. Acute Intermittent Porphyria - S/S - Intermittent abdominal pain (varying degrees of pain) that recurs without leukocytosis or fever. The pain typically resolves completely between attacks. Other symptoms include peripheral neuropathy, seizures, altered level of consciousness, and even psychosis. Acute Intermittent Porphyria - Labs & Imaging - A CMP is useful to rule out elevated LFTs and to evaluate for profound hyponatremia (common finding). The finding of elevated levels of porphobilinogen in the urine during an acute attack is diagnostic for AIP. Note that the urine may be clear/normal in color when first voided but will turn dark upon being exposed to air and light. Acute Intermittent Porphyria - Treatment - Avoid known triggers, especially barbiturates and sulfonamides. See Table 40-1 on page 1691 (Papadakis and McPhee, 2018) for additional medications. Starvation or other low carbohydrate diets (including prolonged fasts) can exacerbate or trigger symptoms.