BioChem C785 - WGU - Module 2 - all questions and Answers with Verified Solutions

BioChem C785 - WGU - Module 2 - all questions and Answers with Verified Solutions A dehydration reaction builds a polypeptide, where as a hydrolysis reaction breaks a polypeptide Correct Answer- True A misfolded protein can: Correct Answer- 1. can protein aggregation 2. lose normal function 3. can be degraded by the cell 4. can be the result of denaturation A substrate binds to an enzyme at a specific site is referred to as Correct Answer- an active site After learning about Alzheimer's disease and one of the drugs used in its treatment, what other drug design strategies could you use to offer treatment for AD? Correct Answer- 1. Drugs that break up the amyloid plaques 2. Drugs that block the production of amyloid beta peptide 3. drugs that inhibits the aggregation of protein structures Aggregation of the proteins is the main reason behind many neurodegenerative diseases. What mutations will likely cause a neurodegenerative disease? Correct Answer- Replacing a polar amino acid with a non polar amino acid Alkaline phosphatase is produced by bone and liver in the human body. The amount of alkaline phosphatase in blood can help identify if a patient potentially has certain types of bone and/or liver-related disease, including Paget disease, hepatitis, and certain types of cancer. The optimal pH range for alkaline phosphatase activity is a pH of 8.0 to 10.0. What happens to the activity of the alkaline phosphatase at a pH of 2? Correct Answer- Significantly decreases