WGU D027 PathoPharm (100% Error-free Answers)

Mechanism of Action for loop diuretics correct answers block water reasborption in the loop of Henle of nephron. Increases urine output Suffix for loop correct answers -emide ex: furosemide cautions in using loop diuretics correct answers decreased potassium, decreased BP, ototoxicity, nephrotoxicity USE WITH CAUTION in those who have auditory/renal impairments Suffix for Thiazide Diuretics correct answers -thiazide MOA for thiazide diuretics correct answers blood water reabsorption in distal tube of nephron-- increases urine output adverse drug reactions for thiazide diuretics correct answers decreases potassium, increases uric acid, increases calcium AVOID use in hx with gout, use cautiously with kidney disease Contraindicator for thiazide diuretics correct answers those with sulfa allergies, contains sulfa group in molecular structure. Also avoid in hx of gout due to increase of uric acid Aldosterone antagonists MOA correct answers inhibits aldosterone which results in sodium loss in the nephron, water follows and is excreted, potassium is retained (potassium sparing diuretic) example of an aldosterone antagonist correct answers Spironolactone adverse drug reactions for aldosterone antagonists correct answers high potassium, androgen blocking (blocks testosterone and causes estrogen effects) beta blocker examples correct answers Propranolol (Inderal) Metroprolol (Lopressor/Toprol XL) Atenolol (Tenormin) Carvedilol (Coreg) MOA of beta blockers correct answers block adrenergic effects of Beta 1 and Beta 2 receptors (cause cholinergic effects) result in low HR and Low BP Contraindicators for beta blockers correct answers chronic respiratory conditions (particularly for beta 2 blockers) HR 60 bpm disguises hypoglycemia symptoms