GMS 6401 Mock Exam Questions and Answers 100% Pass

GMS 6401 Mock Exam Questions and Answers 100% Pass The kidney consists of specialized vascular and tubular structures (the nephron) which collaborate in the production of urine: - Answer- The glomerular capillary is surrounded by an epithelial structure which forms the beginning of the tubule. A diagnostic renal clearance experiment is conducted and the following steady state (= equilibrium) measurements are obtained on a 34 year old male subject, weighing 60 kg (assume that the renal plasma flow (RPF) is the same as the effective renal plasma flow (ERPF): Urine inulin = 200 mg/100ml Plasma inulin = 4 mg/100ml Urine flow (V) = 2ml/min Urine PAH = 1200 mg/100ml Plasma PAH = 6 mg/100ml - Answer- GFR = 100ml/min Any substance which is freely filtered at the glomerulus, is reabsorbed and is not secreted, will have a renal clearance that is: Choose one best answer. - Answer- Less than the clearance of inulin An increased protein excretion (proteinuria) can indicate glomerular damage. Which of the following changes are likely to cause proteinuria? Choose 1 best answer: - Answer- Loss of nephrin from the epithelial slit pore diaphragm Maintenance of a high glomerular filtration rate (GFR) is required for optimal kidney function. Which of the following options would be most likely to associate with a below optimal GFR in man? - Answer- A low glomerular capillary water permeability A selective increase in renal plasma flow (RPF) due to parallel relaxation of theafferent and efferent arterioles leads to: (Choose one best answer.) - Answer- A rise in GFR with no change in filtration fraction An increase in renal blood flow will lead to which of the following changes within the kidney: (Choose one best answer.) - Answer- Increased total renal oxygen consumption but little change in the renal venous oxygen content (arterial - venous difference) In which tubule segment is there active sodium reabsorption by the Na/K/2Cl (NKCC2) transporter but never any water reabsorption? - Answer- Thick ascending limb of the loop of Henle