PAEA General Surgery EOR Exam tested and passed graded A+

PAEA General Surgery EOR Exam tested and passed graded A+ what are the 2 conditions under the inflammatory bowel disease umbrella? ANS-1. ulcerative colitis 2. crohn's dz in comparing ulcerative colitis and crohn's dz, which is: -limited to the colon w/ rectum always involved *VS* mouth to anus -transmural *VS* mucosa/submucosa involved -LLQ *VS* RLQ pain -bloody diarrhea *VS* non -complications of perianal dz, strictures, fistulas & granulomas *VS* colon cancer & toxic megacolon -colonoscopy showing "skip lesions" & cobblestoning *VS* ulceration & pseudopolyps -barium studies showing "stovepipe sign" (loss of haustral markings) *VS* "string sign" narrowing through scarred areas -(+)P-ANCA *VS* (+)ASCA (anti saccharomyces cerevisiae Ab) -curative *VS* noncurative ANS-1. *ulcerative colitis*- colon/rectum, mucosa/submucosa, LLQ pain, bloody diarrhea, comps of colon cancer & toxic megacolon, colonoscopy w/ ulcerations & pseudopolyps, "stovepipe sign" (loss of haustral markings), (+)P-ANCA, curative 2. *crohn's dz*- mouth to anus, transmural, RLQ pain, nonbloody diarrhea, comps of perianal dz, strictures, fistulas, granulomas, "skip lesions" & "cobblestoning", "string sign", (+)ASCA, noncurative what are the best studies of choice for ulcerative colitis vs crohn's dz in acute dz? ANS--UC: *flex sigmoidoscopy* in acute dz (colonoscopy and barium enema CONTRAINDICATED in acute dz bc can cause perf or toxic megacolon) -crohn's dz: *upper GI series* (barium swallow) in acute dz what medications are used to treat ulcerative colitis and crohn's dz? ANS-1. 5-aminosalicylic acids (anti-inflammatory) *oral mesalamine* best for maintenance, topical mesalamine (rectal suppositories & enemas), *sulfasalzine* (give w/ folic acid); *all of these work best in the colon- so are better for tx'ing UC* 2. *corticosteroids* in *acute flares* only 3. immune modifying agents: 6-mercaptopurine, azathioprine and MTX 4. anti-TNF agents- adalimumab, infliximab certolizumab