NU 578 Unit 4 Test With Latest 100%Correct Answers.

NU 578 Unit 4 Test With Latest 100%Correct Answers. Insulin use - ANSWER Insulin is used to treat all patients with type 1 and many with type 2 diabetes. consists of two amino acid chains (a acidic and b basic) linked by two disulfide bridges. it is synthesized in the pancreas by b ce;;s within islets of langerhans. insulin is released by rise in blood sugar (eating a. meal). Anaolic reaction (insulin promotes conservation of energy and buildup of energy stores) Insulin metabolic actions - ANSWER Insulin promotes glucose into glycogen, amino acids assembled into proteins, fatty acids into triglycerides. Insulin deficiency promotes glycogen into glucose, proteins into amino acids, and fats into glycerol. Metformin use - ANSWER Biguanide used for type 2 DM. oral anti diabetic. may be used with other drugs. can be used for prevention of type 2 diabetes, GDM, PCOS. Reduces GI absorbance of glucose and hepatic production of glucose. Does not stimulate insulin release from the pancreas. Increases HDL, decreases BP, promotes weight loss. DPP-4 Inhibitors (gliptins) - ANSWER go to pancreas and increase insulin release. NU 578 Unit 4 Test With Latest 100%Correct Answers Example is Sitaglitpin Sodium Glucose cotransporter 2 inhibitors (SGLT-2 inhibitors). (gliflozins) - ANSWER Example: empagliflozin increases urine excretion of glucose, taken PO, reduces cardiovascular risk of type 2 diabetes. SE: yeast infections and genital gangrene Incretin Mimetics ('tides) - ANSWER injectables that slow gastric emptying, causes weight loss and help an overwhelmed pancreas. solfonylureas - ANSWER stimulate pancreas to release more insulin. range in onset, duration, and potency and are only used for type 2 diabetes. there are first generation and second generation. second are more potent and doses are lower and drug drug interactions are less common AE: hypoglycemia Acarbose - ANSWER a glucosidase inhibitor oral anti diabetic agent that inhibits breakdown of oligosaccharides into monosaccharides. this delays digestion and prolongs absorption of carbs and decreases postprandial hyperglycemia!! ADR: FI upset and flatulence. take this with first bite of each meal. Insulin Complications/ Drug Interactions - ANSWER hypoglycemia caused by overdose. hypoglycemic agents (sulfonylureas, glinides, and alcohol), hyperglycemia agents, b adrenergic blocking agents. Sitagliptin - ANSWER DP4 inhibitor.